Results 11 to 20 of about 24,517 (227)
Conformational dynamics of AcrA govern multidrug efflux pump assembly.
Multidrug efflux pumps of pathogenic, Gram-negative bacteria comprise an innate resistance mechanism and are key contributors to the emerging global pandemic of antibiotic resistance.
Anthony Hazel +6 more
semanticscholar +4 more sources
Defining the RND-binding residues of AcrA
The resistance-nodulation-division (RND) family of efflux pumps confer clinically relevant antibiotic resistance in Gram-negative bacteria, such as Salmonella enterica.
Ilyas Alav +3 more
semanticscholar +2 more sources
ACRA Perfusion Study: The Impact of Transradial Intervention on Digital Hand Perfusion [PDF]
Background: Transradial intervention (TRI) may impair digital perfusion with hand dysfunction as a result. However, the effect of TRI on digital perfusion has never been investigated, including the influence of variations of the collateral arterial ...
M. V. van Leeuwen +8 more
semanticscholar +6 more sources
TolC-AcrA complex formation monitored by time dependent single-channel electrophysiology.
Characterizing protein-protein interaction on a single molecular level is a challenge, experimentally as well as interpretation of the data. For example, Gram-negative bacteria contain protein complexes spanning the outer and inner cell wall devoted to efflux effectively cell toxic substances.
I. Bodrenko +5 more
semanticscholar +4 more sources
Optimization of zofimarin production by an endophytic fungus, Xylaria sp. Acra L38 [PDF]
To optimize the medium for high zofimarin production, sucrose maltose, glucose, tryptone and peptone were used in an orthogonal array design experiment, where the highest value of zofimarin produced was 25.6 μg/mL.
Jirapan Chaichanan +4 more
semanticscholar +5 more sources
Background Resistance-nodulation-division (RND) efflux pumps are important mediators of antibiotic resistance. RND pumps, including the principal multidrug efflux pump AcrAB-TolC in Salmonella, are tripartite systems with an inner membrane RND ...
Ilyas Alav, Vassiliy N. Bavro, J. Blair
semanticscholar +1 more source
Escala de Estrategias de Aprendizaje ACRA-Abreviada para Alumnos Universitarios
Introducción. El objetivo de nuestro trabajo estuvo centrado en efectuar la validación de una versión abreviada de la Escala ACRA, con alumnos universitarios. La Escala ACRA original es un instrumento diseñado para la evaluación de las estrategias de aprendizaje, muy utilizado en el ámbito hispanoparlante. No obstante, tanto su extensión como su ámbito
J. Arias, F. Justicia
semanticscholar +4 more sources
The current COVID-19 pandemic has led the world to an unprecedented global shortage of ventilators, and its sharing has been proposed as an alternative to meet the surge.
P. Otero +10 more
semanticscholar +1 more source
AcrB-AcrA Fusion Proteins That Act as Multidrug Efflux Transporters [PDF]
ABSTRACT The AcrAB-TolC system in Escherichia coli is an intrinsic RND-type multidrug efflux transporter that functions as a tripartite complex of the inner membrane transporter AcrB, the outer membrane channel TolC, and the adaptor protein AcrA.
K. Hayashi +6 more
semanticscholar +3 more sources

