Results 21 to 30 of about 24,517 (227)
Efflux Pump-Binding 4(3-Aminocyclobutyl)Pyrimidin-2-Amines Are Colloidal Aggregators
Biomolecules, 2023 Efflux pumps are a relevant factor in antimicrobial resistance. In E. coli, the tripartite efflux pump AcrAB-TolC removes a chemically diverse set of antibiotics from the bacterium.
Tania Szal +8 more
doaj +1 more source
Conformational restriction shapes the inhibition of a multidrug efflux adaptor protein
Nature Communications, 2023 Membrane efflux pumps play a major role in bacterial multidrug resistance. The tripartite multidrug efflux pump system from Escherichia coli, AcrAB-TolC, is a target for inhibition to lessen resistance development and restore antibiotic efficacy, with ...
Benjamin Russell Lewis +11 more
doaj +1 more source
Regular Combinators for String Transformations [PDF]
, 2014 We focus on (partial) functions that map input strings to a monoid such as the set of integers with addition and the set of output strings with concatenation.
Alur R. +3 more
core +2 more sources
Australian cardiac rehabilitation exercise parameter characteristics and perceptions of high-intensity interval training: a cross-sectional survey [PDF]
, 2018 Purpose: This study explored current demographics, characteristics, costs, evaluation methods, and outcome measures used in Australian cardiac rehabilitation (CR) programs.
Byrnes, Joshua +6 more
core +1 more source
Корпоративные финансы, 2017 This research addresses the problem of pension savings and pension reserves management efficiency analysis of the whole Russian pension system and non-state pension funds.
Yury Nogin
doaj +1 more source
A bacterial glycoengineered antigen for improved serodiagnosis of porcine brucellosis [PDF]
, 2016 Brucellosis is a highly zoonotic disease that affects animals and human beings. Brucella suis is the etiological agent of porcine brucellosis and one of the major human brucellosis pathogens.
Balzano, Rodrigo E. +9 more
core +1 more source
Conformational Flexibility in the Multidrug Efflux System Protein AcrA [PDF]
Structure, 2006 Intrinsic resistance to multiple drugs in many gram-negative bacterial pathogens is conferred by resistance nodulation cell division efflux pumps, which are composed of three essential components as typified by the extensively characterized Escherichia coli AcrA-AcrB-TolC system.
Mikolosko, Jonathan +3 more
openaire +2 more sources
Children, 2013 I am very excited about the upcoming launch of Children, a journal dedicated to the streamlined yet scientifically rigorous electronic dissemination of peer-reviewed science related to childhood health and disease in developed and developing countries ...
Sari Acra
doaj +1 more source
Membrane fusion proteins of type I secretion system and tripartite efflux pumps share a binding motif for TolC in gram-negative bacteria. [PDF]
PLoS ONE, 2012 The Hly translocator complex of Escherichia coli catalyzes type I secretion of the toxin hemolysin A (HlyA). In this complex, HlyB is an inner membrane ABC (ATP Binding Cassette)-type transporter, TolC is an outer membrane channel protein, and HlyD is a ...
Minho Lee +5 more
doaj +1 more source
Energies, 2013 A novel artificial cobweb routing algorithm (ACRA) for routing the tree-type physical topology of a low-voltage distribution network in a smart grid is proposed and analyzed in this paper.
Dianguo Xu +3 more
doaj +1 more source