Results 11 to 20 of about 464,635 (262)
Frontiers in Immunology, 2014 Natural Killer cell function is regulated by a balance between activating and inhibitory receptors expressed on their surface. .A relevant effort has focused so far on the study of KIR carriage/expression setting the basis for NK cell education and self ...
Francesco eMarras +4 more
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Frontiers in Immunology, 2014 Natural killer (NK) cells may be important in modulating HIV replication in early course of HIV infection. The effector function of NK cells is finely tuned by a balance between signals delivered by activating and inhibitory receptors.
Archana Gopal Kulkarni +2 more
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Protease Activated Receptors and Arthritis [PDF]
International Journal of Molecular Sciences, 2021 The catabolic and destructive activity of serine proteases in arthritic joints is well known; however, these enzymes can also signal pain and inflammation in joints. For example, thrombin, trypsin, tryptase, and neutrophil elastase cleave the extracellular N-terminus of a family of G protein-coupled receptors and the remaining tethered ligand sequence ...
Flora Lucena, Jason J. McDougall
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Frontiers in Immunology, 2014 In this review I summarize some of the early research on NK cell biology and function that led to the discovery of a totally new receptor system for polymorphic MHC class I molecules.
Bent eRolstad
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The modulation of the cell cycle: a sentinel to alert the NK cells of dangers
Frontiers in Immunology, 2013 Natural killer (NK) cells are an essential component of innate immunity that provides a rapid response to detect stressed, infected, or transformed target cells. This system is controlled by a balance of inhibitory and activating signals transmitted by a
Vincent eVieillard, Florence eBaychelier
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Frontiers in Immunology, 2019 Natural killer (NK) cell function is regulated by a balance between activating and inhibitory receptors, but the details of this receptor interplay are not extensively understood.
Sridharan Ganesan +2 more
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Human NK Cells and Herpesviruses: Mechanisms of Recognition, Response and Adaptation
Frontiers in Microbiology, 2019 NK cells contribute to early defenses against viruses through their inborn abilities that include sensing of PAMPs and inflammatory signals such as cytokines or chemokines, recognition, and killing of infected cells through activating surface receptors ...
Mariella Della Chiesa +9 more
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Frontiers in Molecular Neuroscience, 2023 Membrane guanylyl cyclase receptors are important regulators of local cGMP production, critically influencing cell growth and differentiation as well as ion transport, blood pressure and calcium feedback of vertebrate phototransduction.
Matthias Gesemann +1 more
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BMC Immunology, 2019 Background Natural killer cell responses to virally-infected or transformed cells depend on the integration of signals received through inhibitory and activating natural killer cell receptors.
Alexandra Tremblay-McLean +4 more
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Research Progress on NK Cell Receptors and Their Signaling Pathways
Mediators of Inflammation, 2020 Natural killer cells (NK cells) play an important role in innate immunity. NK cells recognize self and nonself depending on the balance of activating receptors and inhibitory receptors. After binding to their ligands, NK cell receptors trigger subsequent
Yingying Chen +3 more
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