Results 111 to 120 of about 9,358 (229)

Yellow Palm Discoloration After Phenol Exposure

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Phenol exposure typically causes irritant contact dermatitis with yellow‐brown discoloration. A worker developed characteristic discoloration followed by rapidly evolving distant eruptions consistent with an id reaction after phenol exposure. Symptoms resolved with conservative treatment and elimination of exposure.
Makoto Kondo   +3 more
wiley   +1 more source

DAMPs, PAMPs and alarmins: all we need to know about danger. [PDF]

open access: yes, 2007
: Multicellular animals detect pathogens via a set of receptors that recognize pathogenassociated molecular patterns (PAMPs). However, pathogens are not the only causative agents of tissue and cell damage: trauma is another one.
Marco E Bianchi
core  

Allergic conjunctivitis: phenotype, pathophysiology, innate immune pathways, and treatment [PDF]

open access: yesExploration of Asthma & Allergy
Allergic conjunctivitis (AC) is an inflammatory disorder of the ocular surface caused by allergic reactions to environmental substances. It presents with symptoms such as itching, redness of the eye, excessive tearing, and swelling/irritation in the eyes
Tanmay Singhal   +4 more
doaj   +1 more source

Macrophage: Biological Functions, Diseases, and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Macrophages are sentinel innate immune cells that arise from embryonic precursors and bone marrow monocytes, displaying a functional continuum that transcends the classical M1 (pro‐inflammatory)/M2 (anti‐inflammatory) dichotomy. Under homeostatic conditions, balanced M1/M2 polarization preserves tissue integrity by coordinating immune surveillance ...
Bihang Sun   +4 more
wiley   +1 more source

High Amounts of S100-Alarmins Confer Antimicrobial Activity on Human Breast Milk Targeting Pathogens Relevant in Neonatal Sepsis [PDF]

open access: yes, 2017
Sepsis is a leading cause of perinatal mortality worldwide. Breast milk (BM) feeding is protective against neonatal sepsis, but the molecular mechanisms remain unexplained.
Dorothee Viemann   +7 more
core   +1 more source

Contact sensitisers activate keratinocytes and induce cytotoxicity via Transient Receptor Potential Ankyrin 1 in allergic contact dermatitis

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 16, Page 4610-4627, August 2026.
Abstract Background and Purpose Allergic contact dermatitis (ACD) is a frequent inflammatory skin disease with limited therapeutic options. While neuronal Transient Receptor Potential Ankyrin 1 (TRPA1) has been implicated in ACD, the role of keratinocyte TRPA1 remains unclear.
Areej Jaber   +8 more
wiley   +1 more source

Identification of epithelial alarmins that promote activation of primary human lung fibroblasts [PDF]

open access: yes, 2013
PhD ThesisBackground Activation of the innate immune system plays a key role in exacerbations of chronic lung disease, yet the role of fibroblasts in innate immune responses and the identity of danger signals (alarmins) that may contribute to their ...
Suwara, Monika Iwona
core  

Plasma Elastase Screening in Hematological Disease Reveals Its Potential as a Diagnostic and Prognostic Biomarker in Hematological Malignancies

open access: yesInternational Journal of Laboratory Hematology, Volume 48, Issue 4, Page 795-806, August 2026.
ABSTRACT Introduction Neutrophil‐extracellular traps are net‐like material released by triggered neutrophils and composed of decondensed chromatin linked to nuclear proteins. Elastase, one of the fourth most represented neutrophil‐specific serine proteases stored in azurophil granules of naïve neutrophils, exerts various actions, including degradation ...
Pasqualina Scala   +14 more
wiley   +1 more source

Immunohistochemical Evaluation of TLR‐4, HSP‐70 and Caspase‐3 Expressions in Lesional Areas of Ecthyma Disease

open access: yesVeterinary Dermatology, Volume 37, Issue 4, Page 549-556, August 2026.
Background: Contagious ecthyma (Orf) is a highly contagious, economically significant disease affecting sheep, goats and wild small ruminants, caused by the resilient Orf virus (ORFV). It produces thick, crusted lesions around the mouth and nostrils, especially in animals aged 3–4 months, sometimes causing near 100% mortality in immunocompromised young
Emine Nur Dincer, Ozlem Ozmen
wiley   +1 more source

IL‐33/ST2 Signaling Sustains Hepato‐Intestinal Homeostasis by Orchestrating Vascular Surveillance and Immune Regulatory Circuits During Experimental Trypanosoma cruzi Infection

open access: yesThe FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Impairment of hepato‐intestinal homeostasis triggered by ST2 deficiency during T. cruzi infection. Within the splenic compartment, immune dysregulation is marked by a robust pro‐inflammatory polarization of the T‐cell landscape. In the liver, ST2 deficiency is associated with hepatocellular injury, increased parasite burden, and hyperalbuminemia ...
Marcelo Eduardo Cardozo   +22 more
wiley   +1 more source

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