Results 11 to 20 of about 47,878 (245)

Innate Immune Evasion of Alphaherpesvirus Tegument Proteins [PDF]

open access: yesFrontiers in Immunology, 2019
Alphaherpesviruses are a large family of highly successful human and animal DNA viruses that can establish lifelong latent infection in neurons. All alphaherpesviruses have a protein-rich layer called the tegument that, connects the DNA-containing capsid
Linjiang Yang   +68 more
doaj   +3 more sources

Alphaherpesvirus Subversion of Stress-Induced Translational Arrest [PDF]

open access: yesViruses, 2016
In this article, we provide an overview of translational arrest in eukaryotic cells in response to stress and the tactics used specifically by alphaherpesviruses to overcome translational arrest.
Renée L. Finnen, Bruce W. Banfield
doaj   +3 more sources

Cytoskeletons in the Closet—Subversion in Alphaherpesvirus Infections [PDF]

open access: yesViruses, 2018
Actin filaments, microtubules and intermediate filaments form the cytoskeleton of vertebrate cells. Involved in maintaining cell integrity and structure, facilitating cargo and vesicle transport, remodelling surface structures and motility, the ...
Christopher E. Denes   +3 more
doaj   +3 more sources

2012 Colorado alphaherpesvirus latency symposium [PDF]

open access: bronzeJournal of NeuroVirology, 2012
Randall J. Cohrs, Don Gilden
openalex   +3 more sources

Structural Insights Into the Nuclear Import of Gallid Alphaherpesvirus 1 Large Tegument Protein. [PDF]

open access: yesMicrobiologyopen
The study identifies and characterizes a bipartite nuclear localization signal within the GaAHV‐1 UL36 large tegument protein, revealing its structural interaction with importin α/β1 and confirming a conserved mechanism of nuclear import through biochemical, crystallographic, and mutational analyses.
Nath BK   +7 more
europepmc   +2 more sources

Alphaherpesvirus Vaccines [PDF]

open access: yesCurrent Issues in Molecular Biology, 2020
Prophylactic and therapeutic vaccines for the alphaherpesviruses including varicella zoster virus (VZV) and herpes simplex virus types 1 and 2 have been the focus of enormous preclinical and clinical research. A live viral vaccine for prevention of chickenpox and a subunit therapeutic vaccine to prevent zoster are highly successful.
Aschner, Clare Burn, Herold, Betsy C.
openaire   +2 more sources

Mammalian alphaherpesvirus miRNAs [PDF]

open access: yesBiochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2011
Mammalian alphaherpesviruses are major causes of human and veterinary disease. During productive infection, these viruses exhibit complex and robust patterns of gene expression. These viruses also form latent infections in neurons of sensory ganglia in which productive cycle gene expression is highly repressed.
Jurak, Igor, Griffiths, A., Coen, D.M.
openaire   +5 more sources

Alphaherpesvirus glycoprotein E: A review of its interactions with other proteins of the virus and its application in vaccinology

open access: yesFrontiers in Microbiology, 2022
The viral envelope glycoprotein E (gE) is required for cell-to-cell transmission, anterograde and retrograde neurotransmission, and immune evasion of alphaherpesviruses.
Yaru Ning   +51 more
doaj   +1 more source

Alphaherpesvirus Genomics: Past, Present and Future [PDF]

open access: yesCurrent Issues in Molecular Biology, 2020
Alphaherpesviruses, as large double-stranded DNA viruses, were long considered to be genetically stable and to exist in a homogeneous state. Recently, the proliferation of high-throughput sequencing (HTS) and bioinformatics analysis has expanded our understanding of herpesvirus genomes and the variations found therein.
Kuny, Chad V., Szpara, Moriah L.
openaire   +2 more sources

A Screening for Virus Infections in Eight Herds of Semi-domesticated Eurasian Tundra Reindeer (Rangifer tarandus tarandus) in Norway, 2013–2018

open access: yesFrontiers in Veterinary Science, 2021
Background: Previous serological screenings have indicated that Eurasian semi-domesticated tundra reindeer (Rangifer tarandus tarandus) in Finnmark, Northern Norway, are exposed to alphaherpesvirus, gammaherpesvirus and pestivirus. Alphaherpesvirus (i.e.,
Morten Tryland   +10 more
doaj   +1 more source

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