Results 11 to 20 of about 47,878 (245)
Innate Immune Evasion of Alphaherpesvirus Tegument Proteins [PDF]
Alphaherpesviruses are a large family of highly successful human and animal DNA viruses that can establish lifelong latent infection in neurons. All alphaherpesviruses have a protein-rich layer called the tegument that, connects the DNA-containing capsid
Linjiang Yang +68 more
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Alphaherpesvirus Subversion of Stress-Induced Translational Arrest [PDF]
In this article, we provide an overview of translational arrest in eukaryotic cells in response to stress and the tactics used specifically by alphaherpesviruses to overcome translational arrest.
Renée L. Finnen, Bruce W. Banfield
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Cytoskeletons in the Closet—Subversion in Alphaherpesvirus Infections [PDF]
Actin filaments, microtubules and intermediate filaments form the cytoskeleton of vertebrate cells. Involved in maintaining cell integrity and structure, facilitating cargo and vesicle transport, remodelling surface structures and motility, the ...
Christopher E. Denes +3 more
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2012 Colorado alphaherpesvirus latency symposium [PDF]
Randall J. Cohrs, Don Gilden
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Structural Insights Into the Nuclear Import of Gallid Alphaherpesvirus 1 Large Tegument Protein. [PDF]
The study identifies and characterizes a bipartite nuclear localization signal within the GaAHV‐1 UL36 large tegument protein, revealing its structural interaction with importin α/β1 and confirming a conserved mechanism of nuclear import through biochemical, crystallographic, and mutational analyses.
Nath BK +7 more
europepmc +2 more sources
Alphaherpesvirus Vaccines [PDF]
Prophylactic and therapeutic vaccines for the alphaherpesviruses including varicella zoster virus (VZV) and herpes simplex virus types 1 and 2 have been the focus of enormous preclinical and clinical research. A live viral vaccine for prevention of chickenpox and a subunit therapeutic vaccine to prevent zoster are highly successful.
Aschner, Clare Burn, Herold, Betsy C.
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Mammalian alphaherpesvirus miRNAs [PDF]
Mammalian alphaherpesviruses are major causes of human and veterinary disease. During productive infection, these viruses exhibit complex and robust patterns of gene expression. These viruses also form latent infections in neurons of sensory ganglia in which productive cycle gene expression is highly repressed.
Jurak, Igor, Griffiths, A., Coen, D.M.
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The viral envelope glycoprotein E (gE) is required for cell-to-cell transmission, anterograde and retrograde neurotransmission, and immune evasion of alphaherpesviruses.
Yaru Ning +51 more
doaj +1 more source
Alphaherpesvirus Genomics: Past, Present and Future [PDF]
Alphaherpesviruses, as large double-stranded DNA viruses, were long considered to be genetically stable and to exist in a homogeneous state. Recently, the proliferation of high-throughput sequencing (HTS) and bioinformatics analysis has expanded our understanding of herpesvirus genomes and the variations found therein.
Kuny, Chad V., Szpara, Moriah L.
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Background: Previous serological screenings have indicated that Eurasian semi-domesticated tundra reindeer (Rangifer tarandus tarandus) in Finnmark, Northern Norway, are exposed to alphaherpesvirus, gammaherpesvirus and pestivirus. Alphaherpesvirus (i.e.,
Morten Tryland +10 more
doaj +1 more source

