Regulation of alphaherpesvirus infections by the ICP0 family of proteins [PDF]
, 2013 Immediate-early protein ICP0 of herpes simplex virus type 1 (HSV-1) is important for the regulation of lytic and latent viral infection. Like the related proteins expressed by other alphaherpesviruses, ICP0 has a zinc-stabilized RING finger domain that ...
Boutell, Chris, Everett, Roger
core +1 more source
Pollens destroy respiratory epithelial cell anchors and drive alphaherpesvirus infection [PDF]
, 2019 Pollens are well-known triggers of respiratory allergies and asthma. The pollen burden in today's ambient air is constantly increasing due to rising climate change and air pollution.
Gevaert, Kris +6 more
core +3 more sources
The Cholesterol Transport Inhibitor U18666A Interferes with Pseudorabies Virus Infection
Viruses, 2022 Many viruses require the maintenance of lysosomal cholesterol homeostasis for a successful infection; however, the role of lysosomal cholesterol homeostasis in the alphaherpesvirus life cycle is not clear.
Byeongwoon Song
doaj +1 more source
Investigation of the frequency and selected prevalence factors of equid alphaherpesvirus 4 viremia in horses with acute onset of fever and respiratory signs. [PDF]
J Vet Diagn InvestPusterla N +4 more
europepmc +3 more sources
On-site detection of equid alphaherpesvirus 3 in perineal and genital swabs of mares and stallions [PDF]
, 2018 Equine coital exanthema (ECE) is an infectious, venereally transmitted muco-cutaneous disease affecting mares and stallions, caused by equid alphaherpesvirus 3 (EHV3).
Barrandeguy, María Edith +8 more
core +1 more source
Scientific Reports, 2021 We have formerly shown that glycoprotein C (gC) of Gallid alphaherpesvirus 2, better known as Marek’s disease (MD) alphaherpesvirus (MDV), is required for interindividual spread in chickens.
Widaliz Vega-Rodriguez +5 more
doaj +1 more source
Porcine NK cells stimulate proliferation of pseudorabies virus-experienced CD8+ and CD4+ CD8+ T cells [PDF]
, 2018 Natural killer (NK) cells belong to the innate immune system and play a central role in the defense against viral infections and cancer development, but also contribute to shaping adaptive immune responses.
De Pelsmaeker, Steffi +3 more
core +4 more sources
Replication of Marek's Disease Virus Is Dependent on Synthesis of De Novo Fatty Acid and Prostaglandin E2 [PDF]
, 2019 Marek’s disease virus (MDV) causes deadly lymphoma and induces an imbalance of the lipid metabolism in infected chickens. Here, we discovered that MDV activates the fatty acid synthesis (FAS) pathway in primary chicken embryo fibroblasts (CEFs).
Behboudi, Shahriar +3 more
core +1 more source
New therapeutic approaches to the alphaherpesvirus infections [PDF]
Journal of Antimicrobial Chemotherapy, 1997 The character of diseases caused by alphaherpesviruses has changed over the last decade. The severity of disease and the frequency of acyclovir resistance has increased with the increase in the number of immunocompromised patients. Compounding the trend towards more virulent herpes disease is the current emphasis towards outpatient management of many ...
K A, Cassady, R J, Whitley
openaire +2 more sources
Frontiers in Immunology, 2022 Type I and III Interferons (IFNs) are the initial antiviral cytokines produced in response to virus infection. These IFNs in turn bind to their respective receptors, trigger JAK-STAT signaling and induce the expression of IFN-stimulated genes (ISGs) to ...
Yue Yin +4 more
doaj +1 more source