Results 41 to 50 of about 47,553 (202)

Porcine NK cells stimulate proliferation of pseudorabies virus-experienced CD8+ and CD4+ CD8+ T cells [PDF]

, 2018
Natural killer (NK) cells belong to the innate immune system and play a central role in the defense against viral infections and cancer development, but also contribute to shaping adaptive immune responses.
De Pelsmaeker, Steffi, De Regge, Nick, Devriendt, Bert, Favoreel, Herman   +3 more
core   +4 more sources

Pseudorabies virus-induced expression and antiviral activity of type I or type III interferon depend on the type of infected epithelial cell

Frontiers in Immunology, 2022
Type I and III Interferons (IFNs) are the initial antiviral cytokines produced in response to virus infection. These IFNs in turn bind to their respective receptors, trigger JAK-STAT signaling and induce the expression of IFN-stimulated genes (ISGs) to ...
Yue Yin, Jinglin Ma, Cliff Van Waesberghe, Bert Devriendt, Herman W. Favoreel   +4 more
doaj   +1 more source

Replication of Marek's Disease Virus Is Dependent on Synthesis of De Novo Fatty Acid and Prostaglandin E2 [PDF]

, 2019
Marek’s disease virus (MDV) causes deadly lymphoma and induces an imbalance of the lipid metabolism in infected chickens. Here, we discovered that MDV activates the fatty acid synthesis (FAS) pathway in primary chicken embryo fibroblasts (CEFs).
Behboudi, Shahriar, Boodhoo, Nitish, Kamble, Nitin, Kaufer, Benedikt B.   +3 more
core   +1 more source

New therapeutic approaches to the alphaherpesvirus infections [PDF]

Journal of Antimicrobial Chemotherapy, 1997
The character of diseases caused by alphaherpesviruses has changed over the last decade. The severity of disease and the frequency of acyclovir resistance has increased with the increase in the number of immunocompromised patients. Compounding the trend towards more virulent herpes disease is the current emphasis towards outpatient management of many ...
K A, Cassady, R J, Whitley
openaire   +2 more sources

Central nervous system disease and genital disease in harbor porpoises (Phocoena phocoena) are associated with different herpesviruses [PDF]

, 2016
Herpesvirus infection causes disease of variable severity in many species, including cetaceans. However, little is known about herpesvirus infection in harbor porpoises (Phocoena phocoena), despite being widespread in temperate coastal waters of the ...
Bildt, M.W.G. (Marco) van de, De Jong, A. (Anton), Elk, C.E. (Niels) van, Getu, S. (Sarah), Kuiken, T. (Thijs), Osterhaus, A.D.M.E. (Albert), Run, P.R.W.A. (Peter) van, Verjans, G.M.G.M. (George)   +7 more
core   +1 more source

Valproic Acid and Its Amidic Derivatives as New Antivirals against Alphaherpesviruses

Viruses, 2020
Herpes simplex viruses (HSVs) are neurotropic viruses with broad host range whose infections cause considerable health problems in both animals and humans.
Sabina Andreu, Inés Ripa, Raquel Bello-Morales, José Antonio López-Guerrero   +3 more
doaj   +1 more source

Immune- and nonimmune-compartment-specific interferon responses are critical determinants of herpes simplex virus-induced generalized infections and acute liver failure [PDF]

, 2016
The interferon (IFN) response to viral pathogens is critical for host survival. In humans and mouse models, defects in IFN responses can result in lethal herpes simplex virus 1 (HSV-1) infections, usually from encephalitis.
Leib, David A, Parker, George A, Parker, Zachary M, Pasieka, Tracy Jo   +3 more
core   +3 more sources

The precise function of alphaherpesvirus tegument proteins and their interactions during the viral life cycle

Frontiers in Microbiology
Alphaherpesvirus is a widespread pathogen that causes diverse diseases in humans and animals and can severely damage host health. Alphaherpesvirus particles comprise a DNA core, capsid, tegument and envelope; the tegument is located between the nuclear ...
Yuxi Cui, Yuxi Cui, Yuxi Cui, Yuxi Cui, Yuxi Cui, Mingshu Wang, Mingshu Wang, Mingshu Wang, Mingshu Wang, Mingshu Wang, Anchun Cheng, Anchun Cheng, Anchun Cheng, Anchun Cheng, Anchun Cheng, Wei Zhang, Qiao Yang, Qiao Yang, Qiao Yang, Qiao Yang, Qiao Yang, Bin Tian, Bin Tian, Bin Tian, Bin Tian, Bin Tian, Xumin Ou, Xumin Ou, Xumin Ou, Xumin Ou, Xumin Ou, Juan Huang, Juan Huang, Juan Huang, Juan Huang, Juan Huang, Ying Wu, Ying Wu, Ying Wu, Ying Wu, Ying Wu, Shaqiu Zhang, Shaqiu Zhang, Shaqiu Zhang, Shaqiu Zhang, Shaqiu Zhang, Di Sun, Di Sun, Di Sun, Di Sun, Di Sun, Yu He, Yu He, Yu He, Yu He, Yu He, Xinxin Zhao, Xinxin Zhao, Xinxin Zhao, Xinxin Zhao, Xinxin Zhao, Zhen Wu, Zhen Wu, Zhen Wu, Zhen Wu, Zhen Wu, Dekang Zhu, Dekang Zhu, Dekang Zhu, Dekang Zhu, Renyong Jia, Renyong Jia, Renyong Jia, Renyong Jia, Renyong Jia, Shun Chen, Shun Chen, Shun Chen, Shun Chen, Shun Chen, Mafeng Liu, Mafeng Liu, Mafeng Liu, Mafeng Liu, Mafeng Liu   +84 more
doaj   +1 more source

Access to a main alphaherpesvirus receptor, located basolaterally in the respiratory epithelium, is masked by intercellular junctions [PDF]

, 2017
The respiratory epithelium of humans and animals is frequently exposed to alphaherpesviruses, originating from either external exposure or reactivation from latency.
Hussey, Gisela S, Laval, Kathlyn, Maes, Roger, Nauwynck, Hans, Poelaert, Katrien, Van Cleemput, Jolien, Van Den Broeck, Wim   +6 more
core   +3 more sources

2015 Colorado Alphaherpesvirus Latency Society Symposium [PDF]

Journal of NeuroVirology, 2015
Meeting Report on the 9th Annual Symposium of the Colorado Alphaherpesvirus Latency Society (CALS) held on May 8–11, 2019, in Vail, CO.
Randall J. Cohrs, Don Gilden
openaire   +2 more sources