Results 191 to 200 of about 782,609 (335)

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Characterization of the initial C3 convertase of the alternative pathway of human complement. [PDF]

, 1984
Zvi Fishelson, Michael K. Pangburn, Hans J. Müller‐Eberhard   +2 more
openalex   +1 more source

Alternative pathways to low carbon mobility

, 2013
Low carbon mobility is defined as mobility that results in substantially lower levels of carbon consumption and emissions. Here, mobility is defined as the total amount of travel that is undertaken on all forms of transport (Chapter 1), and carbon is used to illustrate the various negative environmental impacts from transport (Chapter 11). As discussed
openaire   +2 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Correction: A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement. [PDF]

J Biol Chem, 2023
Jensen RK, Pihl R, Gadeberg TAF, Jensen JK, Andersen KR, Thiel S, Laursen NS, Andersen GR.   +7 more
europepmc   +1 more source

In vitro activation of the alternative pathway of complement by settled grain dust

, 1978
Stephen A. Olenchock, Judith C. Mull, Pervis C. Major, M J Peach, Mary E. Gladish, Geoffrey Taylor   +5 more
openalex   +1 more source

Activation of the alternative pathway of complement by mycobacteria and cord factor [PDF]

, 1980
V. D. Ramanathan, Jeffrey L. Curtis, J.L. Turk   +2 more
openalex   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Pediatric Immunodeficiency Caused by Complement Classical and Alternative Pathway Defects Due to a Homozygous CFI Variant: A Case Report. [PDF]

Cureus
Wei J, Liu C, Tian M, Cao G, Li J.
europepmc   +1 more source

Correction to: Mathematical Modelling of Alternative Pathway of Complement System. [PDF]

Bull Math Biol, 2021
Bakshi S, Cunningham F, Nichols EM, Biedzka-Sarek M, Neisen J, Petit-Frere S, Bessant C, Bansal L, Peletier LA, Zamuner S, van der Graaf PH.   +10 more
europepmc   +1 more source