Results 61 to 70 of about 23,258 (194)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Changes in protein nutritional quality as affected by processing of millet supplemented with Moringa seed flour

Journal of the Saudi Society of Agricultural Sciences, 2018
Pearl millet flour was supplemented with 5%, 10% and 15% defatted Moringa seeds flour (DMSF). Raw and supplemented flour were fermented and/or cooked for 0, 8 and 16 h.
Azhari A. Mohammed Nour, Awad R. Mohamed, Oladipupo Q. Adiamo, Elfadil E. Babiker   +3 more
doaj   +1 more source

Utilization of ileal digestible amino acids by growing pigs: threonine [PDF]

British Journal of Nutrition, 1991
An experiment was conducted to determine the utilization of ileal digestible threonine by growing pigs. Three threonine-deficient diets (0.22 g ileal digestible threonine/MJ digestible energy (DE)) were formulated using cottonseed meal, meat-and-bone meal and soya-bean meal respectively, as the only source of threonine in the diet.
S A, Beech, E S, Batterham, R, Elliott
openaire   +4 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Protein Digestibility of Cereal Products

Foods, 2019
Protein digestibility is currently a hot research topic and is of big interest to the food industry. Different scoring methods have been developed to describe protein quality. Cereal protein scores are typically low due to a suboptimal amino acid profile
Iris Joye
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

The in vitro determination of the protein quality of rumen microorganisms of cows on urea-rich feed

Agricultural and Food Science, 1979
The amino acid composition, essential amino acid index (EAA-I), pepsin-pancreatin in vitro digestibility and pepsin-pancreatin-digest-residue-index (PPDR-I) of the rumen bacterial and protozoal protein of cows fed urea and ammonium salts as their sole ...
Eeva-Liisa Syväoja, Matti Kreula
doaj  

Meat protein quality of Dormitator latifrons (Pisces: Eleotridae): arguments for use by rural communities

Ecosistemas y Recursos Agropecuarios, 2019
The objective of this study was to evaluate the quality of meat protein of Dormitator latifrons for humans based on its Protein Digestibility Corrected Amino Acid Score (PDCAAS).
Mao Ernesto Rafael Basto-Rosales, Olimpia Carrillo-Farnés, Cynthia Eugenia Montoya-Martínez, Daniel Badillo-Zapata, Gustavo Gustavo Rodríguez-Montes de Oca, Carlos Alfonso Álvarez-González, Héctor Nolasco-Soria, Fernando Vega Villasante   +7 more
doaj   +1 more source

Digestible sulfur amino acid requirement of starting turkeys

Poultry Science, 1997
Three experiments (a total of 1,020 poults) were conducted to determine the digestible sulfur amino acid (SAA) requirement for female turkey poults during the starter period. Poults were fed a standard corn-soybean meal diet (PC) that met or exceeded NRC recommendations (28% CP, 3,172 kcal MEn/kg) for 1 wk and were then randomly assigned to treatments ...
S D, Boling, J D, Firman
openaire   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source