Results 71 to 80 of about 2,406 (250)

Stabilized amorphous solid dispersions with small molecule excipients

, 2014
Chapter 21.
Holger Grohganz, Korbinian Löbmann, Riikka Laitinen, Clare J. Strachan, Jensen, Katrine Birgitte Tarp, Strachan, Clare, Katrine Tarp Jensen, Löbmann, Korbinian, Laitinen, Riikka, Thomas Rades, Rades, Thomas, Grohganz, Holger   +11 more
core   +1 more source

Manufacturing Amorphous Solid Dispersions with Improved Solid-State Stability

, 2021
Although amorphous solid dispersion(ASD) is a promising strategy for enhancing drug solubility, it has not been recognized to its full potential due to a lack of understanding as to how solid state stability is affected by manufacturing conditions such as method of preparation, formulation parameters (choice of excipients, drug-polymer ratio ...
openaire   +1 more source

Development and characterization of nifedipine-amino methacrylate copolymer solid dispersion powders with various adsorbents

Asian Journal of Pharmaceutical Sciences, 2017
Solid dispersions of nifedipine (NDP), a poorly water-soluble drug, and amino methacrylate copolymer (AMCP) with aid of adsorbent, that is, fumed silica, talcum, calcium carbonate, titanium dioxide, and mesoporous silica from rice husks (SRH), were ...
Yotsanan Weerapol, Sontaya Limmatvapirat, Jurairat Nunthanid, Srisuda Konthong, Supakij Suttiruengwong, Pornsak Sriamornsak   +5 more
doaj   +1 more source

Development and Characterization of Solid Dispersion for Dissolution Improvement of Furosemide by Cogrinding Method [PDF]

Advanced Pharmaceutical Bulletin, 2014
Purpose: The purpose of this study was to prepare and characterize solid dispersion formulation of furosemide to enhance dissolution rate. Methods: Solid dispersions with different drug: carrier ratios were prepared by cogrinding method using ...
Mohammad Reza Siahi-Shadbad, Saeed Ghanbarzadeh, Mohammad Barzegar-Jalali, Hadi Valizadeh, Alireza Taherpoor, Ghobad Mohammadi, Azim Barzegar-Jalali, Khosro Adibkia   +7 more
doaj   +1 more source

Cathodic Cage Plasma Deposition of Nanostructured Cu–Fe–Se Coatings on Poly(methyl Methacrylate)

Advanced Engineering Materials, EarlyView.
Nanostructured Cu–Fe–Se coatings are deposited on PMMA by a modified cathodic cage plasma process, enabling low‐temperature deposition on polymer substrates. A transition from discontinuous to compact morphology is observed with temperature, with optimal properties at 200°C, where improved CuFeSe2‐type bonding, lowest sheet resistance, and favorable ...
V. S. S. Sobrinho, M. Naeem, T. H. C. Costa, M. S. Libório, J. C. A. Queiroz, C. B. B. Luna, R. R. M. Sousa, P. S. Vieira, E. M. Araújo   +8 more
wiley   +1 more source

An Experimental High‐Throughput Approach for the Screening of Hard Magnet Materials

Advanced Engineering Materials, EarlyView.
An entire workflow for the high‐throughput characterization and analysis of compositionally graded magnetic films is presented. Characterization protocols, data management tools and data analysis approaches are illustrated with test case Sm(Fe, V)12 based films.
William Rigaut, Pierre Le Berre, Hamdi Jaballah, Lukas Fink, Victor Poline, Richard Haettel, Stéphane Grenier, Gilbert Chahine, Ewen Bellec, Guillaume Buatier, Wilfried Hortschitz, Santa Pile, Thomas Schrefl, Nils Blanc, Yuan Hong, Thibaut Devillers, Nora M. Dempsey   +16 more
wiley   +1 more source

Natural Bone‐Derived Ceramic Scaffolds Functionalized with Chitosan‐Gold, Chitosan‐Magnesium, and Chitosan‐Zinc for Enhanced Antibacterial Activity

Advanced Engineering Materials, EarlyView.
This study reports the development of antibacterial ceramic scaffolds derived from natural bovine bone. The bones were processed through sequential boiling and hydrogen peroxide treatment to remove organic matter, producing porous, mineral‐rich scaffolds.
Mohamad Hassan Taherian, Anh Thi Le, Anh Thi Van Le, Dung My Thi Dang, Tin Chanh Duc Doan, Chien Mau Dang, Martin Bolduc   +6 more
wiley   +1 more source

Physicochemical characterisation of spray dried ternary solid dispersions of simvastatin. Processability, tableting and dissolution

British Journal of Pharmacy, 2019
Simvastatin(SMV) is poorly soluble drug classified as belonging to Class II of Biopharmaceutics Classification System. Common approach to improve apparent solubility of drugs is production of amorphous solid dispersions (ASD) by means of spray drying(SD)
Hanan Abdalmaula, Anant Paradkar, Krzysztof J Paluch   +2 more
doaj   +1 more source

Molecular Dynamics Studies of Shape Memory Polymers: From Bead–Spring Models to Atomistic Simulations

Advanced Engineering Materials, EarlyView.
Coarse‐grained (left) and atomistic (right) models of the shape memory polymer ESTANE ETE 75DT3 are shown schematically. The two representations bridge molecular detail and mesoscopic description. Both models capture shape memory behavior, linking segmental mobility and conformational relaxation of anisotropic chains to macroscopic recovery, and ...
Fathollah Varnik
wiley   +1 more source

Mechanical Properties and Tableting Behavior of Amorphous Solid Dispersions [PDF]

Journal of Pharmaceutical Sciences, 2017
Amorphous solid dispersions (ASDs) consisting of acetaminophen (APAP) and copovidone were systematically studied to identify effects of drug loading and moisture content on mechanical properties, thermal properties, and tableting behavior. ASDs containing APAP at different levels were prepared by film casting and characterized by differential scanning ...
Sarsvat, Patel, Xiang, Kou, Hao Helen, Hou, Ye Bill, Huang, John C, Strong, Geoff G Z, Zhang, Changquan Calvin, Sun   +6 more
openaire   +2 more sources