Results 61 to 70 of about 33,115 (300)
Micro-Injection Moulding of PEO/PCL Blend–Based Matrices for Extended Oral Delivery of Fenbendazole
Pharmaceutics, 2023 Fenbendazole (FBZ) is a broad-spectrum anthelmintic administered orally to ruminants; nevertheless, its poor water solubility has been the main limitation to reaching satisfactory and sustained levels at the site of the target parasites.
Gilberto S. N. Bezerra +5 more
doaj +1 more source
Manufacturing Amorphous Solid Dispersions with Improved Solid-State Stability
, 2021 Although amorphous solid dispersion(ASD) is a promising strategy for enhancing drug solubility, it has not been recognized to its full potential due to a lack of understanding as to how solid state stability is affected by manufacturing conditions such as method of preparation, formulation parameters (choice of excipients, drug-polymer ratio ...
openaire +1 more source
Manufacturing strategies to develop amorphous solid dispersions: An overview [PDF]
Journal of Drug Delivery Science and Technology, 2020 Since the past several decades, poor water solubility of existing and new drugs in the pipeline have remained a challenging issue for the pharmaceutical industry. Literature describes several approaches to improve the overall solubility, dissolution rate, and bioavailability of drugs with poor water solubility.
Nicole, Mendonsa +6 more
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Advanced Engineering Materials, EarlyView.Powder metal processing provides scalable advantages in nanoporous (np) metal development. Mechanical alloying is used to produce unique precursors for hybrid nanopore formation by oxide reduction and dealloying. As demonstrated in np Ag, this approach improves process efficiency while promoting smaller ligaments and larger pores, both of which are ...
Mark A. Atwater, Oliver A. Fowler
wiley +1 more source
Pharmaceutics, 2021 Amorphization serves as a strategy for the improvement of poor dissolution characteristics of many drug compounds. However, in many formulations the content of polymeric stabilizer is high, which is undesirable from the perspective of future applications.
Joanna Szafraniec-Szczęsny +9 more
doaj +1 more source
Physical properties and solubility studies of Nifedipine-PEG 1450/HPMCAS-HF solid dispersions [PDF]
, 2018 Low-order high-energy nifedipine (NIF) solid dispersions (SDs) were generated by melt solvent amorphization with polyethylene glycol (PEG) 1450 and hypromellose acetate succinate (HPMCAS-HF) to increase NIF solubility while achieving acceptable physical ...
Chougule, Mahavir B. +6 more
core +1 more source
High-dielectric constant and wide band gap inverse silver oxide phases of the ordered ternary alloys of SiO$_{2}$, GeO$_{2}$ and SnO$_{2}$ [PDF]
, 2006 High-dielectric constant and wide band gap oxides have important technological applications. The crystalline oxide polymorphs having lattice constant compatibility to silicon are particularly desirable.
Bulutay, C., Sevik, C.
core +2 more sources
Advanced Engineering Materials, EarlyView.Stabilization of L‐PBF Ni50.7Ti49.3 under low‐cycle loading was investigated. Recoverable strain after cycling was dependent on the amount of applied load. Recovery ratio was 53.4% and 35.1% at intermediate and high load, respectively. The maximum total strain reached 10.3% at a high load of 1200 MPa.
Ondřej Červinek +5 more
wiley +1 more source
Engineering of Nanofibrous Amorphous and Crystalline Solid Dispersions for Oral Drug Delivery
Pharmaceutics, 2018 Poor aqueous solubility (<0.1 mg/mL) affects a significant number of drugs currently on the market or under development. Several formulation strategies including salt formation, particle size reduction, and solid dispersion approaches have been ...
Laura Modica de Mohac +3 more
doaj +1 more source
Synthesis and Optical Properties of Cu2CoSnS4 Colloidal Quantum Dots [PDF]
, 2011 Monodisperse quaternary chalcopyrite Cu2CoSnS4 colloidal quantum dots have been synthesized by acid peptization of a tailored Cu2CoSnS4 precursor displaying loosely packed, ultrafine primary crystallites.
Balocchi, Andréa +4 more
core +2 more sources