Results 71 to 80 of about 310 (140)

Enhancing Antibacterial Efficacy: Combining Novel Bacterial Topoisomerase Inhibitors with Efflux Pump Inhibitors and Other Agents Against Gram-Negative Bacteria. [PDF]

Antibiotics (Basel)
Zorman M, Kokot M, Zdovc I, Senerovic L, Mandic M, Zidar N, Cotman AE, Durcik M, Peterlin Mašič L, Minovski N, Anderluh M, Hrast Rambaher M.   +11 more
europepmc   +1 more source

Spirohydantoin derivatives exert dopamine D₂-like receptor-independent cytotoxicity in glioblastoma cells with possible involvement of calpain inhibition. [PDF]

Sci Rep
Kucwaj-Brysz K, Podlewska S, Jakubowska K, Mąsior A, Wilczkowski M, Duszyńska B, Drukała J, Handzlik J, Jantas D.   +8 more
europepmc   +1 more source

Synthesis and evaluation of arylpiperazines derivatives of 3,5-dioxo-(2H,4H)-1,2,4-triazine as 5-HT1AR ligands. [PDF]

Bioorg Med Chem Lett, 2014
Kumar JSD, Majo VJ, Prabhakaran J, Mann JJ.   +3 more
europepmc   +1 more source

Uncovering the unique characteristics of different groups of 5-HT_5AR ligands with reference to their interaction with the target protein. [PDF]

Pharmacol Rep
Kordylewski SK, Bugno R, Bojarski AJ, Podlewska S.   +3 more
europepmc   +1 more source

Pharmacophore Comparison and Development of Recently Discovered Long Chain Arylpiperazine and Sulfonamide Based 5-HT7 Ligands. [PDF]

Mini Rev Med Chem, 2018
Rague A, Tidgewell K.
europepmc   +1 more source

New pyrimidine derivatives as potential agents against hepatocellular carcinoma: design, synthesis, and <i>in vitro</i> and <i>in vivo</i> biological evaluations. [PDF]

Front Pharmacol
Bertrand J, Montorfano I, Pérez-Castro R, Valdés-Valdés R, Romero J, Delgado T, Brito I, Santibáñez JF, Cabrera AR, Vieytes MP, Echeverría J, Salas CO, Echeverría C.   +12 more
europepmc   +1 more source

Therapeutic Role of Heterocyclic Compounds in Neurodegenerative Diseases: Insights from Alzheimer's and Parkinson's Diseases. [PDF]

Neurol Int
Puranik N, Song M.
europepmc   +1 more source

The Universal 3D QSAR Model for Dopamine D₂ Receptor Antagonists. [PDF]

Int J Mol Sci, 2019
Zięba A, Żuk J, Bartuzi D, Matosiuk D, Poso A, Kaczor AA.   +5 more
europepmc   +1 more source

Discovery and Preliminary SAR of Arylpiperazines as Novel, Brainpenetrant Antiprion Compounds. [PDF]

ACS Med Chem Lett, 2013
Li Z, Gever J, Rao S, Widjaja K, Prusiner SB, Silber BM.   +5 more
europepmc   +1 more source

Multi-Target Approach for Drug Discovery against Schizophrenia. [PDF]

Int J Mol Sci, 2018
Kondej M, Stępnicki P, Kaczor AA.
europepmc   +1 more source