Results 51 to 60 of about 1,751 (156)

A microtubule-dynein tethering complex regulates the axonemal inner dyneinf(I1)

Molecular Biology of the Cell, 2018
Motility of cilia/flagella is generated by a coordinated activity of thousands of dyneins. Inner dynein arms (IDAs) are particularly important for the formation of ciliary/flagellar waveforms, but the molecular mechanism of IDA regulation is poorly understood. Here we show using cryoelectron tomography and biochemical analyses of Chlamydomonas flagella
Kubo, Tomohiro, Hou, Yuqing, Cochran, Deborah A., Witman, George B., Oda, Toshiyuki   +4 more
openaire   +3 more sources

The Coordination and Regulation of Axonemal Dynein [PDF]

Biophysical Journal, 2017
Molecular motor proteins drive the motility behind cellular dynamics. Recent advances in structural biology and single-molecule biophysics have led to a detailed understanding of many motor protein mechanisms. However, two understudied areas include the regulation and the coordination of motor proteins, particularly axonemal dyneins, which are the ...
openaire   +1 more source

Comparative structural study on axonemal and cytoplasmic dyneins

Cytoskeleton
AbstractAxonemal dyneins are the driving force of motile cilia, while cytoplasmic dyneins play an essential role in minus‐end oriented intracellular transport. Their molecular structure is indispensable for an understanding of the molecular mechanism of ciliary beating and cargo transport.
Noemi Zimmermann, Takashi Ishikawa
openaire   +3 more sources

The role of SPAG1 in the assembly of axonemal dyneins in human airway epithelia.

J Cell Sci, 2022
Smith AJ, Bustamante-Marin XM, Yin W, Sears PR, Herring LE, Dicheva NN, López-Giráldez F, Mane S, Tarran R, Leigh MW, Knowles MR, Zariwala MA, Ostrowski LE.   +12 more
europepmc   +1 more source

C11orf70 Mutations Disrupting the Intraflagellar Transport-Dependent Assembly of Multiple Axonemal Dyneins Cause Primary Ciliary Dyskinesia. [PDF]

Am J Hum Genet, 2018
Fassad MR, Shoemark A, le Borgne P, Koll F, Patel M, Dixon M, Hayward J, Richardson C, Frost E, Jenkins L, Cullup T, Chung EMK, Lemullois M, Aubusson-Fleury A, Hogg C, Mitchell DR, Tassin AM, Mitchison HM.   +17 more
europepmc   +1 more source

Diverse Roles of Axonemal Dyneins in Drosophila Auditory Neuron Function and Mechanical Amplification in Hearing. [PDF]

Sci Rep, 2015
Karak S, Jacobs JS, Kittelmann M, Spalthoff C, Katana R, Sivan-Loukianova E, Schon MA, Kernan MJ, Eberl DF, Göpfert MC.   +9 more
europepmc   +1 more source

Dynein Heavy Chain 9, Axonemal [PDF]

, 2020
openaire   +1 more source

CladeOScope-GSA: Revealing Evolutionary Associations Across Gene Sets. [PDF]

Int J Mol Sci
Braun M, Bloch I, Sherill-Rofe D, Canavati C, Sharon E, Tabach Y.   +5 more
europepmc   +1 more source

Discrete PIH proteins function in the cytoplasmic preassembly of different subsets of axonemal dyneins. [PDF]

J Cell Biol, 2010
Yamamoto R, Hirono M, Kamiya R.
europepmc   +1 more source

Biallelic Truncating DNAH14 Variant in Siblings with Neurodevelopmental Disorder and Predominant Ataxia: Clinical Report and Literature Review. [PDF]

Int J Mol Sci
Baris S, Dogan M, Terali K, Gezdirici A, Eroz R, Yucel PP, Kilic H, Yavas C, Yildirim G, Baris I.   +9 more
europepmc   +1 more source