Results 41 to 50 of about 20,682 (267)

Study on MEV90 of 0.5% ropivacaine for US-guided caudal epidural block in anorectal surgery

open access: yesFrontiers in Medicine, 2023
BackgroundChoosing the appropriate concentration and volume of anesthetics is critical for a successful nerve block. The current study aimed to determine the minimum effective volume (MEV) of 0.5% ropivacaine for US-guided CEB in 90% of patients (MEV90 ...
Pei Zhang   +11 more
doaj   +1 more source

Determination of the 95% effective dose of remimazolam to achieve loss of consciousness during anesthesia induction in different age groups [PDF]

open access: yesKorean Journal of Anesthesiology, 2022
Background Remimazolam is a new ultra short-acting benzodiazepine originally developed as an improved version of midazolam. Recent studies have demonstrated non-inferiority of remimazolam to propofol in general anesthesia.
Juyeon Oh   +6 more
doaj   +1 more source

The distribution of loss in two-treatment biased-coin designs [PDF]

open access: yesBiostatistics, 2003
The paper compares randomized rules of the biased-coin type for the sequential allocation of treatments in a clinical trial. An important characteristic is the loss, which measures the increase in the variance of parameter estimates due to the imbalance caused by randomization. Simulations are used to find the small-sample distribution of loss.
openaire   +2 more sources

Randomness and Noise in Information Systems [PDF]

open access: yes, 2013
This dissertation is devoted to the study of randomness and noise in a number of information systems including computation systems, storage systems, and natural paradigms like molecular systems, where randomness plays important and distinct roles ...
Zhou, Hongchao
core   +1 more source

A study to determine minimum effective dose of oxytocin infusion during caesarean delivery in parturients at high risk of uterine atony

open access: yesJournal of Obstetric Anaesthesia and Critical Care, 2017
Background: Oxytocin, a commonly used drug to prevent uterine atony after caesarean section, should be administered as dilute rapid infusion rather than as a bolus. This study was conducted to calculate ED90 of oxytocin infusion during caesarean delivery
Shashikiran   +3 more
doaj   +1 more source

Covariate-Adaptive Biased Coin Randomization for Master Protocols with Multiple Interventions and Biomarker-Stratified Allocation

open access: yes, 2023
In a multi-arm trial with predefined subgroups for each intervention to target, it is often desirable to enrich assignment to an intervention by enrolling more biomarker-positive participants to the intervention.
Ivanova, Anastasia   +2 more
core   +1 more source

Item Selection With Biased-Coin Up-and-Down Designs [PDF]

open access: yes, 2020
Targeting any arbitrary percentile, the biased-coin up-and-down design is theoretically appealing and can provide an efficient alternative to the current maximum Fisher information method for item selection in adaptive testing. This paper illustrates the
Zhaohui Sheng, Yanyan Sheng
core  

Seamless Clinical Trials with Doubly Adaptive Biased Coin Designs

open access: yesThe New England Journal of Statistics in Data Science, 2023
In addition to scientific questions, clinical trialists often explore or require other design features, such as increasing the power while controlling the type I error rate, minimizing unnecessary exposure to inferior treatments, and comparing multiple treatments in one clinical trial.
Hongjian Zhu   +3 more
openaire   +1 more source

Design of a low cost coin acceptor for vending machine [PDF]

open access: yes, 2021
Coin acceptor is a device that receive and identifies the validity of the coin. It works by analyzing the coin it received based on its mass, size, diameter, thickness, metal composition, and then sends an appropriate signal through the output connection.
Zulkipli, Muhammad   +2 more
core   +1 more source

Spin and Charge Control of Topological End States in Chiral Graphene Nanoribbons on a 2D Ferromagnet

open access: yesAdvanced Materials, EarlyView.
Chiral graphene nanoribbons on a ferromagnetic gadolinium‐gold surface alloy display tunable spin and charge states at their termini. Atomic work function variations and exchange fields enabe transitions between singlet, doublet, and triplet configurations.
Leonard Edens   +8 more
wiley   +1 more source

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