Results 11 to 20 of about 370,500 (265)
Blood brain barrier opening is not just blood-brain barrier opening
Journal of Translational MedicineDeepa Sharma, Gregory J. Czarnota
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Development of the blood-brain barrier. [PDF]
DevelopmentABSTRACT The blood–brain barrier (BBB) is a term used to describe the specialized properties of vasculature in the central nervous system (CNS) that regulate the exchange of ions, molecules and cells, thereby maintaining CNS homeostasis.
Gastfriend BD, Daneman R.
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Cold Spring Harbor Perspectives in Biology, 2015 Blood vessels are critical to deliver oxygen and nutrients to all of the tissues and organs throughout the body. The blood vessels that vascularize the central nervous system (CNS) possess unique properties, termed the blood-brain barrier, which allow these vessels to tightly regulate the movement of ions, molecules, and cells between the blood and the
Richard, Daneman, Alexandre, Prat
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Copper transport to the brain by the blood-brain barrier and blood-CSF barrier [PDF]
Brain Research, 2009 The mechanism of copper (Cu) transport into the brain is unclear. This study evaluated the main species and route of Cu transport into the brain using in situ brain perfusion technique, and assessed the levels of mRNA encoding Cu transporters using real time RT-PCR.
Byung-Sun, Choi, Wei, Zheng
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The dynamic blood–brain barrier [PDF]
The FEBS Journal, 2015 With the endothelium as its central unit, the blood–brain barrier (BBB) is a complex multicellular structure separating the central nervous system (CNS) from the systemic circulation. Disruption of the BBB has now been implicated in a multitude of acute and chronic CNS disorders indicating the potentially devastating effects of BBB breakdown on brain ...
James, Keaney, Matthew, Campbell
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What is the blood–brain barrier (not)? [PDF]
Trends in Immunology, 2007 In 1900, summarizing his experiments with toxins and Ehrlich's earlier observations with intravital dyes, the Berlin physician Lewandowski concluded that "brain capillaries must hold back certain molecules". Illustrating this phenomenon with persuasive beauty, the subsequently evolving metaphor of a 'Bluthirnschranke' (blood-brain barrier, BBB) gained ...
Ingo, Bechmann +2 more
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Transferrin Receptor Mediated Brain Uptake During Ischemia and Reperfusion
Journal of Pharmacy & Pharmaceutical Sciences, 2013 Purpose. Drug delivery by transferrin receptor-mediated transport at the blood-brain barrier has shown beneficial effects in animal models of stroke, but it is unclear whether receptor mediated uptake remains functional in the ischemic tissue.
Jiukuan Hao, Ulrich Bickel
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Harmful Effects of Smoking Cannabis: A Cerebrovascular and Neurological Perspective
Frontiers in Pharmacology, 2019 Apart from being used as a medicine, cannabis or marijuana is the most widely abused recreational drug all over the world. The legalization and decriminalization of cannabis in Canada and various states of USA may be the underlying reason of the ...
Sabrina Rahman Archie +2 more
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Accumulation of GD1α Ganglioside in MDA-MB-231 Breast Cancer Cells Expressing ST6GalNAc V
Molecules, 2015 α-Series gangliosides define a particular sub-class of glycosphingolipids containing sialic acid α2,6-linked to GalNAc residue that was isolated as a minor compound from the brain.
Sandy Vandermeersch +7 more
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