Results 31 to 40 of about 1,264,713 (295)

Interactions between cancer cells and bone microenvironment promote bone metastasis in prostate cancer

open access: yesCancer Communications, 2019
Bone metastasis is the leading cause of death in prostate cancer patients, for which there is currently no effective treatment. Since the bone microenvironment plays an important role in this process, attentions have been directed to the interactions ...
Xiangyu Zhang
doaj   +1 more source

Engineering the tumor microenvironment of colorectal cancer [PDF]

open access: yes, 2014
The tumor microenvironment contributes significantly to the clinical prognosis, especially in CRC. Infiltration by cells from the adaptive immune system (e.g. CD8) has been linked to a better survival independently of TNM-stage.
Hirt, Christian Kurt
core   +1 more source

Bone-targeted nanoplatform enables efficient modulation of bone tumor microenvironment for prostate cancer bone metastasis treatment

open access: yes, 2022
As there is currently no effective therapy for patients with prostate cancer (PCa) bone metastasis, it was stringent to explore the relevant treatment strategies.
Tingting Zhang (264633)   +7 more
core   +1 more source

CD38 and bone marrow microenvironment

open access: yesFrontiers in Bioscience, 2014
This review summarizes the events ruled by CD38 shaping the bone marrow environment, recapitulating old and new aspects derived from the body of knowledge on the molecule. The disease models considered were myeloma and chronic lymphocytic leukemia (CLL).
CHILLEMI, ANTONELLA   +9 more
openaire   +6 more sources

The role of the bone microenvironment in regulating myeloma residual disease and treatment

open access: yesFrontiers in Oncology, 2022
Multiple myeloma is an incurable haematological cancer. The increase in targeted therapies has improved the number of myeloma patients achieving a complete response and improved progression-free survival following therapy. However, a low level of disease
Terry G. Dadzie, Alanna C. Green
doaj   +1 more source

The Localized Ionic Microenvironment in Bone Modelling/Remodelling: A Potential Guide for the Design of Biomaterials for Bone Tissue Engineering

open access: yes, 2023
Bone is capable of adjusting size, shape, and quality to maintain its strength, toughness, and stiffness and to meet different needs of the body through continuous remodeling.
Lan Xiao   +11 more
core   +1 more source

New insights into the biomimetic design and biomedical applications of bioengineered bone microenvironments

open access: yesAPL Bioengineering, 2021
The bone microenvironment is characterized by an intricate interplay between cellular and noncellular components, which controls bone remodeling and repair. Its highly hierarchical architecture and dynamic composition provide a unique microenvironment as
Cláudia S. Oliveira   +2 more
doaj   +1 more source

Fabrication of biphasic cartilage-bone integrated scaffolds based on tissue-specific photo-crosslinkable acellular matrix hydrogels

open access: yesMaterials Today Bio, 2022
The fabrication of biphasic cartilage-bone integrated scaffolds is an attractive alternative for osteochondral repair but has proven to be extremely challenging.
Yujie Hua   +13 more
doaj   +1 more source

Rescue of myeloid lineage-committed preprogenitor cells from cytomegalovirus-infected bone marrow stroma [PDF]

open access: yes, 1991
The effect of murine cytomegalovirus on myelopoiesis was studied in long-term bone marrow culture to find an in vitro correlate for the lethal virus interference with bone marrow reconstitution (W. Mutter, M. J. Reddehase, F. W. Busch, H.-J. Bühring, and
Busch, Friedrich W.   +3 more
core   +1 more source

The last tenascin : insights on tenascin-W functions and regulation [PDF]

open access: yes, 2012
Over the last decade, it became clear that the tumor stroma plays an active role in the process of tumor progression, by interacting with the transformed cells and providing a permissive microenvironment for malignant growth.
Martina, Enrico
core   +1 more source

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