Results 31 to 40 of about 1,264,713 (295)
Bone metastasis is the leading cause of death in prostate cancer patients, for which there is currently no effective treatment. Since the bone microenvironment plays an important role in this process, attentions have been directed to the interactions ...
Xiangyu Zhang
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Engineering the tumor microenvironment of colorectal cancer [PDF]
The tumor microenvironment contributes significantly to the clinical prognosis, especially in CRC. Infiltration by cells from the adaptive immune system (e.g. CD8) has been linked to a better survival independently of TNM-stage.
Hirt, Christian Kurt
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As there is currently no effective therapy for patients with prostate cancer (PCa) bone metastasis, it was stringent to explore the relevant treatment strategies.
Tingting Zhang (264633) +7 more
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CD38 and bone marrow microenvironment
This review summarizes the events ruled by CD38 shaping the bone marrow environment, recapitulating old and new aspects derived from the body of knowledge on the molecule. The disease models considered were myeloma and chronic lymphocytic leukemia (CLL).
CHILLEMI, ANTONELLA +9 more
openaire +6 more sources
The role of the bone microenvironment in regulating myeloma residual disease and treatment
Multiple myeloma is an incurable haematological cancer. The increase in targeted therapies has improved the number of myeloma patients achieving a complete response and improved progression-free survival following therapy. However, a low level of disease
Terry G. Dadzie, Alanna C. Green
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Bone is capable of adjusting size, shape, and quality to maintain its strength, toughness, and stiffness and to meet different needs of the body through continuous remodeling.
Lan Xiao +11 more
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The bone microenvironment is characterized by an intricate interplay between cellular and noncellular components, which controls bone remodeling and repair. Its highly hierarchical architecture and dynamic composition provide a unique microenvironment as
Cláudia S. Oliveira +2 more
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The fabrication of biphasic cartilage-bone integrated scaffolds is an attractive alternative for osteochondral repair but has proven to be extremely challenging.
Yujie Hua +13 more
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Rescue of myeloid lineage-committed preprogenitor cells from cytomegalovirus-infected bone marrow stroma [PDF]
The effect of murine cytomegalovirus on myelopoiesis was studied in long-term bone marrow culture to find an in vitro correlate for the lethal virus interference with bone marrow reconstitution (W. Mutter, M. J. Reddehase, F. W. Busch, H.-J. Bühring, and
Busch, Friedrich W. +3 more
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The last tenascin : insights on tenascin-W functions and regulation [PDF]
Over the last decade, it became clear that the tumor stroma plays an active role in the process of tumor progression, by interacting with the transformed cells and providing a permissive microenvironment for malignant growth.
Martina, Enrico
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