Results 11 to 20 of about 119,730 (291)

Identification of bone morphogenetic protein 4 in the saliva after the placement of fixed orthodontic appliance [PDF]

Progress in Orthodontics, 2021
Background This study was conducted in order to explore the effects of orthodontic tooth movement (OTM) on the changes of salivary proteome. This prospective observational pilot study recruited 12 healthy teenage boys with malocclusion treated with a ...
Lovorka Grgurevic, Ruder Novak, Grgur Salai, Vladimir Trkulja, Lejla Ferhatovic Hamzic, Vojka Zgombic Popovic, Darko Bozic   +6 more
doaj   +2 more sources

Bone Morphogenetic Protein 4 Alleviates DSS-Induced Ulcerative Colitis Through Activating Intestinal Stem Cell by Target ID3 [PDF]

Frontiers in Cell and Developmental Biology, 2021
Damage to intestinal epithelial cell proliferation or intestinal stem cell (ISC) maintenance may trigger inflammatory bowel disease (IBD), and protecting the ISCs is critical for IBD treatment.
Lei Hu, Lei Hu, Lei Hu, Lei Hu, Junji Xu, Junji Xu, Junji Xu, Junji Xu, Xue Wang, Xue Wang, Liang Feng, Liang Feng, Chunmei Zhang, Chunmei Zhang, Chunmei Zhang, Jinsong Wang, Jinsong Wang, Songlin Wang, Songlin Wang, Songlin Wang   +19 more
doaj   +2 more sources

Bone morphogenetic protein 4 rescues the bone regenerative potential of old muscle-derived stem cells via regulation of cell cycle inhibitors [PDF]

Stem Cell Research & Therapy, 2022
Background Bone morphogenetic protein 4 (BMP4) promotes the osteogenic differentiation and the bone regenerative potential of muscle-derived stem cells (MDSCs).
Haizi Cheng, Xueqin Gao, Matthieu Huard, Aiping Lu, Joseph J. Ruzbarsky, Sara Amra, Bing Wang, Johnny Huard   +7 more
doaj   +2 more sources

Correction: Bone morphogenetic protein 4 alleviates nonalcoholic steatohepatitis by inhibiting hepatic ferroptosis [PDF]

Cell Death Discovery, 2022
Xingchun Wang, Bingwei Ma, Xin Wen, Hui You, Chunjun Sheng, Le Bu, Shen Qu   +6 more
doaj   +2 more sources

Therapeutic Potential for Bone Morphogenetic Protein 4 in Human Malignant Glioma

Neoplasia: An International Journal for Oncology Research, 2017
Human glioma, in particular, malignant forms such as glioblastoma exhibit dismal survival rates despite advances in treatment strategies. A population of glioma cells with stem-like features, glioma cancer stem-like cells (GCSCs), contribute to renewal ...
Guifa Xi, Benjamin Best, Barbara Mania-Farnell, Charles David James, Tadanori Tomita   +4 more
doaj   +3 more sources

Matrix Gla protein maintains normal and malignant hematopoietic progenitor cells by interacting with bone morphogenetic protein-4 [PDF]

Heliyon, 2020
Matrix Gla protein (MGP), a modulator of the BMP-SMAD signals, inhibits arterial calcification in a Glu γ-carboxylation dependent manner but the role of MGP highly expressed in a subset of bone marrow (BM) mesenchymal stem/stromal cells is unknown.
Kana Kuronuma, Aya Yokoi, Tomoya Fukuoka, Muneaki Miyata, Akio Maekawa, Satowa Tanaka, Leo Matsubara, Chie Goto, Miki Matsuo, Hao-Wei Han, Mai Tsuruta, Haruka Murata, Hikari Okamoto, Natsumi Hasegawa, Shigetaka Asano, Mitsuhiro Ito   +15 more
doaj   +2 more sources

Bone morphogenetic protein 4 thermosensitive hydrogel inhibits corneal neovascularization by repairing corneal epithelial apical junctional complexes [PDF]

Materials Today Bio
Corneal neovascularization (CNV) is a heavy attribute of blinding disease changes. Existing medications need numerous infusions and have a limited absorption. Investigating novel drugs with safety, efficacy, and convenience is crucial.
Weijin Nan, Sitong Shen, Yongyan Yang, Meiliang Wu, Yuxi He, Ruiting Zhang, Xuejun Cui, Yan Zhang   +7 more
doaj   +2 more sources

Enhanced in vivo osteogenesis by nanocarrier-fused bone morphogenetic protein-4

International Journal of Nanomedicine, 2013
Yasuyuki Shiozaki,1,2 Takashi Kitajima,4 Tetsuro Mazaki,1,2 Aki Yoshida,1 Masato Tanaka,1 Akihiro Umezawa,5 Mariko Nakamura,6 Yasuhiro Yoshida,3 Yoshihiro Ito,4 Toshifumi Ozaki,1 Akihiro Matsukawa2 1Department of Orthopedic Surgery, Okayama University ...
Shiozaki Y, Kitajima T, Mazaki T, Yoshida A, Tanaka M, Umezawa A, Nakamura M, Yoshida Y, Ito Y, Ozaki T, Matsukawa A   +10 more
doaj   +6 more sources

Bone Morphogenetic Protein 4 Gene Therapy in Mice Inhibits Myeloma Tumor Growth, But Has a Negative Impact on Bone [PDF]

JBMR Plus, 2020
Multiple myeloma is characterized by accumulation of malignant plasma cells in the bone marrow. Most patients suffer from an osteolytic bone disease, caused by increased bone degradation and reduced bone formation.
Marita Westhrin, Toril Holien, Muhammad Zahoor, Siv Helen Moen, Glenn Buene, Berit Størdal, Hanne Hella, Huipin Yuan, Joost D deBruijn, Anton Martens, Richard WJ Groen, Fatima Bosch, Ulf Smith, Anne‐Marit Sponaas, Anders Sundan, Therese Standal   +15 more
doaj   +2 more sources

Emerging Role of Bone Morphogenetic Protein 4 in Metabolic Disorders [PDF]

Diabetes, 2021
Bone morphogenetic proteins (BMPs) are a group of signaling molecules that belong to the TGF-β superfamily. Initially discovered for their ability to induce bone formation, BMPs are known to play a diverse and critical array of biological roles. We here focus on recent evidence showing that BMP4 is an important regulator of white/beige adipogenic ...
Ritesh K. Baboota, Matthias Blüher, Ulf Smith   +2 more
openaire   +3 more sources