Results 21 to 30 of about 126,969 (147)

Erysimum cheiri: The potential uterotonic medicinal herb [PDF]

Trends in Pharmaceutical Sciences, 2020
Wallflower (Erysimum cheiri (L.) Crantz) belonging to the family Brassicaceae has been a well-known medicinal herb in Persian medicine. Several cardiotonic steroids have isolated from different parts of this plant.
Ghazaleh Mosleh, Sasan Zaeri, Parmis Badr, Abdolali Mohagheghzadeh   +3 more
doaj   +1 more source

Steroid-associated hip joint collapse in bipedal emus [PDF]

, 2013
In this study we established a bipedal animal model of steroid-associated hip joint collapse in emus for testing potential treatment protocols to be developed for prevention of steroid-associated joint collapse in preclinical settings.
Yi-Xin He (371449), Jian Q. Feng (7244342), Chi-Wai Man (474700), Jiang Peng (474699), Da-Ping Wang (474703), Ying Liu (18461), Xin-Hui Xie (309249), Ling Qin (68169), Daniel Fong (1254939), Yang Chen (9737), Zhong Liu (288945), De-Ming Xiao (474702), Ge Zhang (112487), Ming Lei (161082), Xin-Luan Wang (309250), Le Huang (332269), Li-Zhen Zheng (474698)   +16 more
core   +6 more sources

Synthesis of Cardiotonic Steroids Oleandrigenin and Rhodexin B [PDF]

, 2021
This article describes a concise synthesis of cardiotonic steroids oleandrigenin (7) and its subsequent elaboration into the natural product rhodexin B (2) from the readily available intermediate (8) that could be derived from the ...
Pavel, Nagorny, Zachary, Fejedelem, Nolan, Carney   +2 more
core   +2 more sources

Antiviral activity of ouabain against a Brazilian Zika virus strain

Scientific Reports, 2022
Zika virus (ZIKV) is an emerging arbovirus associated with neurological disorders. Currently, no specific vaccines or antivirals are available to treat the ZIKV infection.
Deyse Cristina Madruga Carvalho, Poliana Gomes da Silva, Willyenne Marília Dantas, Severino Jefferson Ribeiro da Silva, Caroline Targino Alves da Silva, Elton José Ferreira Chaves, Demetrius Antônio Machado de Araújo, Ronaldo Nascimento de Oliveira, Sandra Rodrigues-Mascarenhas, Lindomar José Pena   +9 more
doaj   +1 more source

Neuroinflammation and Neutrophils: Modulation by Ouabain

Frontiers in Pharmacology, 2022
Cardiotonic steroids are natural compounds that present many physiological and pharmacological functions. They bind Na+/K+-ATPase (NKA) modifying cellular ion concentration and trigger cell signaling mechanisms without altering ion balance.
Jacqueline Alves Leite, Luiz Henrique Agra Cavalcante-Silva, Martina Raissa Ribeiro, Geovanni de Morais Lima, Cristoforo Scavone, Sandra Rodrigues-Mascarenhas   +5 more
doaj   +1 more source

The cardiotonic steroid hormone marinobufagenin induces renal fibrosis: implication of epithelial-to-mesenchymal transition

American Journal of Physiology - Renal Physiology, 2009
David J Kennedy, Deepak Malhotra, Alexei Y Bagrov   +2 more
exaly   +2 more sources

Cardiac Glycoside Ouabain Exerts Anticancer Activity via Downregulation of STAT3

Frontiers in Oncology, 2021
Cardiac glycosides are plant-derived steroid-like compounds which have been used for the treatment of cardiovascular diseases. Ouabain, a cardiotonic steroid and specific Na+/K+-ATPase inhibitor, has been rediscovered for its potential use in the ...
Jie Du, Jie Du, Lijun Jiang, Fuqiang Chen, Huantao Hu, Meijuan Zhou   +5 more
doaj   +1 more source

The fate of steroid estrogens: Partitioning during wastewater treatment and onto river sediments [PDF]

, 2010
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2010 Springer Science+Business Media B.V.The partitioning of steroid estrogens in wastewater treatment and receiving waters is likely to ...
Scrimshaw, Mark D., Rachel L. Gomes, Gomes, Rachel L., Scrimshaw, MD, Lester, John N., Lester, JN, John N. Lester, Gomes, RL, Mark D. Scrimshaw, Cartmell, Elise, Elise Cartmell, Cartmell, E   +11 more
core   +1 more source

Independent elaboration of steroid hormone signaling pathways in Metazoans [PDF]

, 2009
Steroid hormones regulate many physiological processes in vertebrates, nematodes and arthropods through binding to nuclear receptors (NR), a metazoan-specific family of ligand-activated transcription factors.
Laudet, Vincent, Vincent Laudet, Baker, Michael E., Chantal Dauphin-Villemant, Demeneix, Barbara A., Markov, Gabriel, V, Gabriel V. Markov, Demeneix, Ba, Tavares, Raquel, Michael E. Baker, Markov, Gv., Raquel Tavares, Barbara A. Demeneix, Dauphin-Villemante, C., Laudet, V., Dauphin-Villemant, Chantal, Tavares, R., Bakerf, Me.   +17 more
core   +1 more source

21-Benzylidene digoxin: a proapoptotic cardenolide of cancer cells that up-regulates Na,K-ATPase and epithelial tight junctions.

PLoS ONE, 2014
Cardiotonic steroids are used to treat heart failure and arrhythmia and have promising anticancer effects. The prototypic cardiotonic steroid ouabain may also be a hormone that modulates epithelial cell adhesion. Cardiotonic steroids consist of a steroid
Sayonarah C Rocha, Marco T C Pessoa, Luiza D R Neves, Silmara L G Alves, Luciana M Silva, Herica L Santos, Soraya M F Oliveira, Alex G Taranto, Moacyr Comar, Isabella V Gomes, Fabio V Santos, Natasha Paixão, Luis E M Quintas, François Noël, Antonio F Pereira, Ana C S C Tessis, Natalia L S Gomes, Otacilio C Moreira, Ruth Rincon-Heredia, Fernando P Varotti, Gustavo Blanco, Jose A F P Villar, Rubén G Contreras, Leandro A Barbosa   +23 more
doaj   +1 more source