Results 31 to 40 of about 126,969 (147)

Removal of steroid estrogens in carbonaceous and nitrifying activated sludge processes [PDF]

open access: yes, 2010
This is the post-print version of the final paper published in Chemosphere. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other
Chiu, TY   +15 more
core   +1 more source

Ouabain-Induced Gene Expression Changes in Human iPSC-Derived Neuron Culture Expressing Dopamine and cAMP-Regulated Phosphoprotein 32 and GABA Receptors

open access: yesBrain Sciences, 2021
Cardiotonic steroids (CTS) are specific inhibitors and endogenous ligands of a key enzyme in the CNS—the Na+, K+-ATPase, which maintains and creates an ion gradient on the plasma membrane of neurons. CTS cause the activation of various signaling cascades
Alexander V. Lopachev   +9 more
doaj   +1 more source

Determination of Endogenous Bufalin in Serum of Patients With Hepatocellular Carcinoma Based on HPLC-MS/MS

open access: yesFrontiers in Oncology, 2020
Bufalin is a cardiotonic steroid and a key active ingredient of the Chinese medicine ChanSu. It has significant anti-tumor activity against many malignancies, including hepatocellular carcinoma (HCC). Previous studies have shown that human bodies contain
Mengfei Han   +6 more
doaj   +1 more source

Research Progress in Pharmacological Activities and Applications of Cardiotonic Steroids

open access: yesFrontiers in Pharmacology, 2022
Cardiotonic steroids (CTS) are a group of compounds existing in animals and plants. CTS are commonly referred to cardiac glycosides (CGs) which are composed of sugar residues, unsaturated lactone rings and steroid cores.
Junwei Ren   +4 more
doaj   +1 more source

Steroids—has the time come to extend their use to AML?

open access: yesJournal of the Egyptian National Cancer Institute, 2021
Background In 2018, leukaemia accounted for 2.6% of all new cancers, it being the 13th most common cause of cancer and the 10th most common cause of cancer death. Glucocorticoids are commonly used in lymphoid leukaemia treatment, where they are cytotoxic.
Mariah Farrugia   +3 more
doaj   +1 more source

Ouabain Reverts CUS-Induced Disruption of the HPA Axis and Avoids Long-Term Spatial Memory Deficits

open access: yesBiomedicines, 2023
Ouabain (OUA) is a cardiotonic steroid that modulates Na+, K+ -ATPase activity. OUA has been identified as an endogenous substance that is present in human plasma, and it has been shown to be associated with the response to acute stress in both animals ...
Jacqueline Alves Leite   +8 more
doaj   +1 more source

P81 Antibody to Cardiotonic Steroid Reduces Blood Pressure and Vascular Fibrosis in Preeclampsia

open access: yesArtery Research, 2020
Background: Previous studies implicated cardiotonic steroids, including Na/K-ATPase inhibitor marinobufagenin (MBG), in the pathogenesis of preeclampsia (PE). We demonstrated that MBG induces fibrosis via mechanism involving inhibition of Fli1, a nuclear
NI Agalakova   +7 more
doaj   +1 more source

Paraoxanase-1 Modulates Cardiotonic Steroid Induced Cardiac Inflammation and Fibrosis in Dahl Salt Sensitive Model of Chronic Kidney Disease

open access: yesTranslation, 2023
Please view the PDF To see the formatted meeting abstract.
Meghana Ranabothu
doaj   +1 more source

Gonadal steroid sulfates and sulfatase : V. Human testicular steroid sulfatase: Partial characterization and possible regulation by free steroids [PDF]

open access: yes, 1972
To elucidate the role of steroid sulfates as precursors of biologically active hormone in the human testis, cleavage of pregnenolone sulfate, dehydroepiandrosterone sulfate and androstenediol-3-sulfate by microsomal preparations was studied.
Payne, Anita H.
core   +1 more source

Influence of operating parameters on the biodegradation of steroid estrogens and nonylphenolic compounds during biological wastewater treatment processes [PDF]

open access: yes, 2009
This document is the unedited author's version of a Submitted Work that was subsequently accepted for publication in Environmental Science & Technology, copyright © American Chemical Society after peer review.
Pollard, S   +7 more
core   +1 more source

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