Results 41 to 50 of about 126,969 (147)
Cardiac Glycosides as Immune System Modulators
Biomolecules, 2021 Cardiac glycosides (CGs) are natural steroid compounds occurring both in plants and animals. They are known for long as cardiotonic agents commonly used for various cardiac diseases due to inhibition of Na+/K+-ATPase (NKA) pumping activity and modulating
Jan Škubník +2 more
doaj +1 more source
CARDIOTONIC ACTIVITY OF CERTAIN STEROIDS AND BILE SALTS
, 1952 The effects of 23 plant and animal steroids, steroid hormones, and bile acids, and nine of their salts or soluble conjugates, have been investigated in isolated frog hearts.
C. W. Gowdey, J. S. Loynes
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Identification of steroid sulfate transport processes in the human mammary gland [PDF]
, 2003 Circulating hormones and local biotransformation of steroid precursors are both sources of estrogen in human mammary tissue. Estrone-3-sulfate (E(1)S) is an important estrogenic form in premenopausal women, and dehydroepiandrosterone sulfate (DHEAS ...
Pizzagalli, F. +5 more
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The use of cardiotonic drugs in neonates
, 2019 There is a distinct lack of age-appropriate cardiotonic drugs, and adult derived formulations continue to be administered, without evidence-based knowledge on their dosing, safety, efficacy, and long-term effects.
Rabe, Heike, Dempsey, Eugene
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Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.Twin natural products. This manuscript describes a concise biomimetic synthesis of twin abeo‐steroids bufogargarizins A and B with an unusual [7.5.6.5] and [5.7.6.5] skeletons in 19 steps (LLS). The described synthetic approach features the application of a bioinspired regiodivergent intramolecular aldol addition reaction and a selective singlet oxygen‐
Zoey J. Surma +7 more
wiley +2 more sources
Marinobufagenin Inhibits Neutrophil Migration and Proinflammatory Cytokines
Journal of Immunology Research, 2019 Cardiotonic steroids, such as ouabain and digoxin, are known to bind to Na+/K+-ATPase and to promote several biological activities, including anti-inflammatory activity.
Deyse C. M. Carvalho +7 more
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Specialized functional diversity and interactions of the Na,K-ATPase
Frontiers in Physiology, 2016 Na,K-ATPase is a protein ubiquitously expressed in the plasma membrane of all animal cells and vitally essential for their functions. A specialized functional diversity of the Na,K-ATPase isozymes is provided by molecular heterogeneity, distinct ...
Igor I. Krivoi, Vladimir V. Matchkov
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JSFA reports, EarlyView.Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed +5 more
wiley +1 more source
3D model of amphioxus steroid receptor complexed with estradiol [PDF]
, 2009 The origins of signaling by vertebrate steroids are not fully understood. An important advance was the report that an estrogen-binding steroid receptor [SR] is present in amphioxus, a basal chordate with a similar body plan as vertebrates.
Michael E. Baker, David J. Chang
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Effects of Ouabain in Ehrlich Tumor Development in vitro and in vivo
Biology, Medicine & Natural Product Chemistry, 2023 Ouabain (OUA) is a cardiotonic steroid with an immunomodulatory and anti-inflammatory role in different experimental models. Currently, the potential antineoplastic effect of OUA has been studied, however, research is needed to better understand OUA role
Amanda Costa Ayres Salmeron +7 more
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