Results 61 to 70 of about 30,081,745 (303)
Cleavage of pro-caspase-1 into caspase-1 by HMPV.
, 2019 THP-1 cells were differenciated into macrophages using PMA (100 ng/ml) before treatment with 10 μM of MCC950 or DMSO (control) and then infected or not with HMPV or HMPV ΔSH at a MOI of 0.001.
Vuong B. Lê (393003) +8 more
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Adipose tissue IL‐18 production is independent of caspase‐1 and caspase‐11
Immunity, Inflammation and DiseaseBackground Inflammation in adipose tissue, resulting from imbalanced caloric intake and energy expenditure, contributes to the metabolic dysregulation observed in obesity.
Luis Román‐Domínguez +4 more
doaj +1 more source
THE ROLE OF INFLAMMASOME AND CASPASE-1 IN REGULATING ADAPTIVE RESPONSE TO OXIDATIVE STRESS IN MOUSE HEPATOCYTES [PDF]
, 2013 In myeloid cells, oxidative stress can induce the activation of caspase-1 through canonical inflammasome signaling, which leads to the release of proinflammatory cytokines IL-1β/IL-18 and a potentially damaging inflammatory response.
Sun, Qian
core
SfDredd cleaved Sf-caspase-1 when transfected in Sf9 cells.
, 2016 Plasmids expressing FLAG-tagged SfDredd and HA-tagged Sf-caspase-1 were co-transfected into Sf9 cells. Mock treated cells, GFP expressed Sf9 cells, and, GFP and Sf-caspase-1 co-expressed Sf9 cells were used as controls.
Andong Wu (201754) +5 more
core +1 more source
Staurosporine induces necroptotic cell death under caspase-compromised conditions in U937 cells [PDF]
, 2012 For a long time necrosis was thought to be an uncontrolled process but evidences recently have revealed that necrosis can also occur in a regulated manner.
Gabor Barna (146087) +20 more
core +2 more sources
Caspase-3 content in SNU-1 cells.
, 2021 Increase in intracellular Caspase-3 compared to blank (untreated) SNU-1 cells upon treatment with 50–5000 nm sized aminated, carboxylated and NF particles for 4 h. Data compared with respect to surface functionalization (A) or particle size (B). All data
Amrita Banerjee (382658) +2 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
PLoS Pathogens, 2020 We investigated the role of the inflammasome effector caspases-1 and -11 during Salmonella enterica serovar Typhimurium infection of murine intestinal epithelial cells (IECs).
Shauna M Crowley +6 more
doaj +1 more source
The Role of Non-canonical and Canonical Inflammasomes in Inflammaging
Frontiers in Molecular Neuroscience, 2022 Neurodegenerative diseases currently affect millions of people worldwide and continues to increase in the expanding elderly population. Neurodegenerative diseases usually involve cognitive decline and are among the top causes of death.
Brianna Cyr +5 more
doaj +1 more source