Results 41 to 50 of about 644 (132)

Mammalian Cell-Line-Expressed CD2v Protein of African Swine Fever Virus Provides Partial Protection against the HLJ/18 Strain in the Early Infection Stage

Viruses, 2023
A cell line expressing the CD2v protein of ASFV was generated. The efficient expression of CD2v protein was determined by immunofluorescence and Western blotting. The CD2v protein was Ni-affinity purified from the supernatant of cell cultures.
Rong-Hong Hua, Jing Liu, Shu-Jian Zhang, Ren-Qiang Liu, Xian-Feng Zhang, Xi-Jun He, Dong-Ming Zhao, Zhi-Gao Bu   +7 more
doaj   +1 more source

Subtle Genetic Shifts of African Swine Fever Virus Among Vietnamese Domestic Swine Following Live-Attenuated Vaccine Commercialization. [PDF]

Transbound Emerg Dis
Since its first incursion in 2019, African swine fever (ASF) has remained a constant threat to the Vietnamese swine industry. The nationwide commercialization and implementation of live‐attenuated vaccines (LAVs), alongside depopulation‐repopulation efforts, necessitate a critical assessment of whether these strategies have driven inadvertent changes ...
Nguyen TC, Tantitaveewattana P, Pamornchainavakul N, Do DT, Kedkovid R, Thanawongnuwech R.   +5 more
europepmc   +2 more sources

Processing and Localization of the African Swine Fever Virus CD2v Transmembrane Protein [PDF]

Journal of Virology, 2011
ABSTRACTThe African swine fever virus (ASFV)-encoded CD2v transmembrane protein is required for the hemadsorption of red blood cells around infected cells and is also required for the inhibition of bystander lymphocyte proliferation in response to mitogens.
Lynnette C, Goatley, Linda K, Dixon
openaire   +2 more sources

Detection of African Swine Fever Virus Genotype II in West Africa (2020) and Its Co-Circulation With Endemic Genotype I: Implications for Pig Production. [PDF]

Transbound Emerg Dis
African swine fever (ASF) is a highly devastating disease of domestic pigs caused by the ASF virus (ASFV). Historically, only ASFV Genotype I was known to circulate in West Africa. However, Genotype II has recently emerged in Nigeria, Ghana, and Benin for the first time. Between 2017 and 2023, suspected ASF outbreaks were reported in Burkina Faso, Côte
Meki IK, Adedeji AJ, Ouoba LB, Koffi YM, Diakité A, Settypalli TBK, Habibata-Zerbo L, Kouakou KV, Diakité MA, Masembe C, Sidi M, Douyeri TO, Dembelé F, Luka HE, Hamidou-Ouandaogo S, Dembelé C, Weka R, Bazimo G, Dakouo M, Olubade TA, Guitti-Kindo M, Traoré C, Gamra O, Guigma D, Sidibé CAK, Hambolu DA, Adama DD, Maïga BMDA, Ogunleye MA, Toluhi A, Maurice N, Couacy-Hymann E, Luka PD, Cattoli G, Lamien CE.   +34 more
europepmc   +2 more sources

Identification of T-cell epitopes in African swine fever virus CD2v and C-type lectin proteins [PDF]

Journal of General Virology, 2019
African swine fever (ASF) is an emerging disease threat for the swine industry worldwide. No ASF vaccine is available, and progress is hindered by lack of knowledge concerning the extent of ASF virus (ASFV) strain diversity and the viral antigens conferring type-specific protective immunity in pigs.
Burmakina, Galina, Malogolovkin, Alexander, Tulman, Edan R, Xu, Weidong, Delhon, Gustavo, Kolbasov, Denis, Rock, Daniel L   +6 more
openaire   +2 more sources

Signal peptide and N-glycosylation of N-terminal-CD2v determine the hemadsorption of African swine fever virus

Journal of Virology, 2023
ABSTRACT African swine fever virus (ASFV) is the cause of African swine fever (ASF), a devastating disease that affects domestic pigs and wild boar and is currently responsible for the largest animal epidemic. One of the characteristics of ASFV infection, but absent in naturally attenuated strains, is hemadsorption (HAD), a phenomenon that ...
Daniel Pérez-Núñez, Raquel García-Belmonte, Elena Riera, Marta H. Fernández-Sesma, Gonzalo Vigara-Astillero, Yolanda Revilla   +5 more
openaire   +3 more sources

The African Swine Fever Virus with MGF360 and MGF505 Deleted Reduces the Apoptosis of Porcine Alveolar Macrophages by Inhibiting the NF-κB Signaling Pathway and Interleukin-1β

Vaccines, 2021
African swine fever virus (ASFV) poses serious threats to the swine industry. The mortality rate of African swine fever (ASF) is 100%, and there is no effective vaccine currently available.
Qi Gao, Yunlong Yang, Weipeng Quan, Jiachen Zheng, Yizhuo Luo, Heng Wang, Xiongnan Chen, Zhao Huang, Xiaojun Chen, Runda Xu, Guihong Zhang, Lang Gong   +11 more
doaj   +1 more source

Investigation of the First African Swine Fever Outbreak in a Domestic Pig Farm in Hong Kong

Transboundary and Emerging Diseases, Volume 2023, Issue 1, 2023., 2023
In this study, we describe the epidemiological investigation of the first African swine fever (ASF) outbreak in a local domestic pig farm in the New Territories of Hong Kong in 2021. In the outbreak farm, several affected pigs presented clinical and pathological signs consistent with ASF, while the remaining pigs showed nonspecific clinical signs or ...
Yun Young Go, Jeremy H. P. Ho, Karina W. S. Tam, Maedeh Kamali, Yiwen Zhang, Candy C. Y. Lau, Song Hao Li, Michael T. Wilson, Zhihao Guo, Runsheng Li, Guoqian Gu, May P. Y. Tse, Fraser I. Hill, Carrie Batten, Amanda Corla, John Flannery, Anne Conan, Christopher J. Brackman, Dirk U. Pfeiffer, Lin-Zhu Ren   +19 more
wiley   +1 more source

In silico prediction of B- and T-cell epitopes in the CD2v protein of african swine fever virus (African swine fever virus, Asfivirus, Asfarviridae)

Вопросы вирусологии, 2020
Introduction. African swine fever virus (ASF) is a large DNA virus that is the only member of the Asfarviridae family. The spread of the ASF virus in the territory of the Russian Federation, Eastern Europe and China indicates the ineffectiveness of ...
Ksenia A. Mima, Elena I. Katorkina, Sergey A. Katorkin, Sodnom Zh. Tsybanov, Aleksandr S. Malogolovkin   +4 more
doaj   +1 more source

Molecular Characterization of African Swine Fever Viruses Circulating in Can Tho City, Vietnam

Veterinary Medicine International, Volume 2023, Issue 1, 2023., 2023
African swine fever (ASF) is a highly contagious and deadly viral disease in domestic and feral pigs. Since 2018, the disease has spread and caused large socioeconomic consequences to the pig industry in several Asian countries including China, Vietnam, and South Korea.
Nguyen Duc Hien, Le Trung Hoang, To My Quyen, Nguyen Phuc Khanh, Lam Thanh Nguyen, Juan G. Chediack   +5 more
wiley   +1 more source