Results 21 to 30 of about 11,198,861 (420)
Control of RNA degradation in cell fate decision
Frontiers in Cell and Developmental Biology, 2023 Cell fate is shaped by a unique gene expression program, which reflects the concerted action of multilayered precise regulation. Substantial research attention has been paid to the contribution of RNA biogenesis to cell fate decisions.
Mingqiang Deng +5 more
doaj +1 more source
scDIOR: single cell RNA-seq data IO software
BMC Bioinformatics, 2022 Background Single-cell RNA sequencing is becoming a powerful tool to identify cell states, reconstruct developmental trajectories, and deconvolute spatial expression.
Huijian Feng, Lihui Lin, Jiekai Chen
doaj +1 more source
Analytical cell size distribution: lineage-population bias and parameter inference [PDF]
J. R. Soc. Interface 19 (2022), 2022 Solving population balance equations, we derive analytical steady-state cell size distributions for single-lineage experiments, such as the mother machine. These experiments are fundamentally different from batch cultures where populations of cells grow freely, and the statistical bias between them is obtained by comparing our results to cell size ...
arxiv +1 more source
c-Jun as a one-way valve at the naive to primed interface
Cell & Bioscience, 2023 Background c-Jun is a proto-oncogene functioning as a transcription factor to activate gene expression under many physiological and pathological conditions, particularly in somatic cells.
Dongwei Li +17 more
doaj +1 more source
Tracking Cells and their Lineages via Labeled Random Finite Sets [PDF]
, 2021 Determining the trajectories of cells and their lineages or ancestries in live-cell experiments are fundamental to the understanding of how cells behave and divide. This paper proposes novel online algorithms for jointly tracking and resolving lineages of an unknown and time-varying number of cells from time-lapse video data.
arxiv +1 more source
Cell lineage statistics with incomplete population trees [PDF]
PRX Life 1, 013014 (2023), 2023 Cell lineage statistics is a powerful tool for inferring cellular parameters, such as division rate, death rate or the population growth rate. Yet, in practice such an analysis suffers from a basic problem: how should we treat incomplete lineages that do not survive until the end of the experiment?
arxiv +1 more source
The NuRD complex cooperates with SALL4 to orchestrate reprogramming
Nature Communications, 2023 Cell fate decision involves rewiring of the genome, but remains poorly understood at the chromatin level. Here, we report that chromatin remodeling complex NuRD participates in closing open chromatin in the early phase of somatic reprogramming.
Bo Wang +19 more
doaj +1 more source
Role of YAP/TAZ in Cell Lineage Fate Determination and Related Signaling Pathways
Frontiers in Cell and Developmental Biology, 2020 The penultimate effectors of the Hippo signaling pathways YAP and TAZ, are transcriptional co-activator proteins that play key roles in many diverse biological processes, ranging from cell proliferation, tumorigenesis, mechanosensing and cell lineage ...
B. Heng +7 more
semanticscholar +1 more source
Cell & Bioscience, 2021 Background Linear ubiquitination is a novel type of ubiquitination that plays important physiological roles in signalling pathways such as tumour necrosis factor (TNF) signalling.
Ruona Shi +5 more
doaj +1 more source
Cell Research, 2020 During embryogenesis, the liver is the site of hepatogenesis and hematopoiesis and contains many cell lineages derived from the endoderm and mesoderm. However, the characteristics and developmental programs of many of these cell lineages remain unclear ...
Xin Wang +7 more
semanticscholar +1 more source