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Cell Identification and Cell Lineage Analysis [PDF]
, 2011 Caenorhabditis elegans is uniquely suited to the analysis of cell lineage patterns. C. elegans has a small number of somatic cells whose position and morphology are almost invariant from animal to animal. Because C. elegans is virtually transparent, cells can be identified in live animals using a simple bright-field microscopy technique, Nomarski ...
Claudiu A, Giurumescu +1 more
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eLife, 2022 In recent years, live-imaging techniques have been developed for the adult midgut of Drosophila melanogaster that allow temporal characterization of key processes involved in stem cell and tissue homeostasis.
Marco Marchetti +2 more
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Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1985 Fixed lineages are the extreme manifestation of the interrelations between cell division pattern, spatial organization and cell differentiation occurring in embryonic development. These relationships are discussed in the light of recent new detailed descriptions of lineages, experimental perturbations and genetic analysis.
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Developmental Biology, 1992 For many years the mechanisms by which skeletal muscles in higher vertebrates come to be composed of diverse fiber types distributed in distinctive patterns has interested cell and developmental biologists. The fiber composition of skeletal muscles varies from class to class and from muscle to muscle within the vertebrates.
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Tracing cell-lineage histories [PDF]
Nature Reviews Genetics, 2018 Three new studies in Nature and Nature Biotechnology report methods for dissecting transcriptomic cell phenotypes and lineage history simultaneously by combining single-cell RNA sequencing (scRNA-seq) with CRISPR-based lineage tracing.
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Cell lineage visualisation [PDF]
Computer Graphics Forum, 2015 AbstractCell lineages describe the developmental history of Cell populations and are produced by combining time‐lapse imaging and image processing. Biomedical researchers study Cell lineages to understand fundamental processes such as Cell differentiation and the pharmacodynamic action of anticancer agents.
Pretorius, A.J. +2 more
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Cell lineage specification at single cell resolution [PDF]
Stem Cell Investigation, 2017 Single cell technology has been widely used in developmental and stem cell biology. In mouse, single cell transcriptome has revealed the cell lineage specification in pre-implantation and post-implantation stage embryo. Now Mohammed et al. investigated the dynamic cell fate commitment during the transition from peri-implantation to early post ...
Jian, Yang, Pentao, Liu
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Cell Lineage Infidelity in PDAC Progression and Therapy Resistance
Frontiers in Cell and Developmental Biology, 2021 Infidelity to cell fate occurs when differentiated cells lose their original identity and either revert to a more multipotent state or transdifferentiate into a different cell type, either within the same embryonic lineage or in an entirely different one.
Antonia Malinova +6 more
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Oligodendrocyte lineage cells and depression [PDF]
Molecular Psychiatry, 2020 AbstractDepression is a common mental illness, affecting more than 300 million people worldwide. Decades of investigation have yielded symptomatic therapies for this disabling condition but have not led to a consensus about its pathogenesis. There are data to support several different theories of causation, including the monoamine hypothesis ...
Butian Zhou +3 more
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Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis +9 more
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