Results 61 to 70 of about 83,983 (175)
The use of deidentified organ donor testes for research
Andrology, EarlyView.Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova +4 more
wiley +1 more source
Molecular Mechanisms Controlling Centriole Duplication
, 2020 Centrioles are barrel shaped, non-membrane bound organelles that typically exist in pairs where the younger ‘daughter’ centriole emanates orthogonally off of the proximal end of the older ‘mother’ centriole.
Boese, Cody
core +5 more sources
Cells, 2020 Centrioles are microtubule-based cellular structures present in most human cells that build centrosomes and cilia. Proliferating cells have only two centrosomes and this number is stringently maintained through the temporally and spatially controlled ...
Catherine Sullenberger +3 more
doaj +1 more source
Sperm Head–Tail Coupling Apparatus Diversity and Common Themes Among Species
Andrology, EarlyView.ABSTRACT Background A stable connection between the sperm head (containing the nucleus and acrosome) and tail (containing the axoneme, mitochondrial sheath, and periaxonemal structures) is critical for fertility. This connection is mediated by a series of nuclear, cytoplasmic, and centriole components that make up the head–tail coupling apparatus (HTCA)
Danielle B. Buglak +2 more
wiley +1 more source
Mechanisms of Centriole Duplication and Spindle Assembly in Human Cells [PDF]
, 2019 The centrosome is the major microtubule-organizing center in animal cells. Centrosomes duplicate once and only once per cell cycle thereby ensuring that two centrosomes are present in mitosis, each of them organizing one of the two spindle poles ...
Wu, Qianzhu
core +2 more sources
Polo-like kinase 4: the odd one out of the family
Cell Division, 2010 Polo-like kinase 4 (PLK4) is a unique member of the Polo-like family of kinases that shares little homology with its siblings and has an essential role in centriole duplication.
Bornens Michel, Sillibourne James E
doaj +1 more source
The evolutionary origins of streptophyte multicellularity
New Phytologist, Volume 251, Issue 5, Page 2365-2383, September 2026.The phylogeny of streptophytes and the deep origin of branching filamentous growth. Summary Over their more than 1 billion years of evolutionary history, streptophytes have repeatedly transitioned between unicellular, simple multicellular and complex multicellular forms.
Tatyana Darienko +10 more
wiley +1 more source
The conversion of centrioles to centrosomes: essential coupling of duplication with segregation [PDF]
Journal of Cell Biology, 2011 Centrioles are self-reproducing organelles that form the core structure of centrosomes or microtubule-organizing centers (MTOCs). However, whether duplication and MTOC organization reflect innate activities of centrioles or activities acquired conditionally is unclear.
Wang, Won-Jing +3 more
openaire +2 more sources
The FASEB Journal, Volume 40, Issue 14, 31 July 2026.The identification of a patient carrying a novel homozygous p.(Gln206Ter) POC5 variant revealed a metabolic phenotype associated with POC5 deficiency. POC5 deficiency disrupts centriolar architecture and ciliary organization, leading to impaired proliferation, premature cellular senescence, and reduced insulin signaling.
Valeria Pistorio +10 more
wiley +1 more source
SAS-6 Assembly Templated by the Lumen of Cartwheel-less Centrioles Precedes Centriole Duplication [PDF]
Developmental Cell, 2014 Centrioles are 9-fold symmetric structures duplicating once per cell cycle. Duplication involves self-oligomerization of the centriolar protein SAS-6, but how the 9-fold symmetry is invariantly established remains unclear. Here, we found that SAS-6 assembly can be shaped by preexisting (or mother) centrioles.
Fong, Chii Shyang +4 more
openaire +3 more sources