Results 1 to 10 of about 19,457 (193)

Design, in silico and pharmacological evaluation of a peptide inhibitor of BACE-1 [PDF]

Frontiers in Pharmacology, 2023
Introduction: Alzheimer’s disease (AD) is the main type of dementia, caused by the accumulation of amyloid plaques, formed by amyloid peptides after being processed from amyloid precursor protein (APP) by γ- and ß-secretases (BACE-1).
Renata Boldin, Renata Boldin, Bianca Cestari Zychar, Luis Roberto C. Gonçalves, Juliana Mozer Sciani   +4 more
doaj   +2 more sources

Light Emitting Diode Photobiomodulation Enhances Oxidative Redox Capacity in Murine Macrophages Stimulated with <i>Bothrops jararacussu</i> Venom and Isolated PLA₂s. [PDF]

Biomed Res Int, 2022
Photobiomodulation therapy associated with conventional antivenom treatment has been shown to be effective in reducing the local effects caused by bothropic venoms in preclinical studies. In this study, we analyzed the influence of photobiomodulation using light emitting diode (LED) on the oxidative stress produced by murine macrophages stimulated with
Dos Reis VP, da Silva Setúbal S, Ferreira E Ferreira AA, Santana HM, Silva MDS, Sousa OO, Boeno CN, Soares AM, Zamuner SR, Zuliani JP.   +9 more
europepmc   +2 more sources

Box Jellyfish (Cnidaria, Cubozoa) Extract Increases Neuron's Connection: A Possible Neuroprotector Effect. [PDF]

Biomed Res Int, 2021
Neurodegenerative diseases are one of the major causes of death worldwide, characterized by neurite atrophy, neuron apoptosis, and synapse loss. No effective treatment has been indicated for such diseases so far, and the search for new drugs is being increased in the last years.
Arruda GLM, Vigerelli H, Bufalo MC, Longato GB, Veloso RV, Zambelli VO, Picolo G, Cury Y, Morandini AC, Marques AC, Sciani JM.   +10 more
europepmc   +2 more sources

Pharmaceutical Applications of Metal Complexes and Derived Materials [PDF]

Pharmaceutics
Medicinal Inorganic Chemistry has demonstrated incomparable potential in the design and development of metal complexes and related materials for a wide spectrum of pharmaceutical applications, including those for therapeutic, diagnostic, and theranostic ...
Pedro Ivo da Silva Maia
doaj   +2 more sources

Avaliação de compostos bioativos em pessegada

Revista Segurança Alimentar e Nutricional, 2019
O objetivo deste trabalho foi selecionar algumas cultivares de pêssego para produção de polpa e, após um período de armazenamento, elaborar massa de pêssego doce, avaliando as características físicas, químicas, microbiológicas e o teor de compostos ...
Maria Ines Rodrigues Machado, Magna da Gloria Lameiro, Adriana Rodrigues Machado, Rui Carlos Zambiazi, José Valmir Feitosa   +4 more
doaj   +3 more sources

Synthesis and anti-inflammatory activity of new alkyl-substituted phthalimide 1H-1,2,3-triazole derivatives. [PDF]

ScientificWorldJournal, 2012
Four new 1,2,3‐triazole phthalimide derivatives with a potent anti‐inflammatory activity have been synthesized in the good yields by the 1,3‐dipolar cycloaddition reaction from N‐(azido‐alkyl)phthalimides and terminal alkynes. The anti‐inflammatory activity was determined by injecting carrageenan through the plantar tissue of the right hind paw of ...
Assis SP, da Silva MT, de Oliveira RN, Lima VL.   +3 more
europepmc   +2 more sources

Determinação dos compostos bioativos da gabiroba

Agrarian, 2018
O bioma Cerrado apresenta uma rica variedade de espécies frutíferas detentoras de características sensoriais e nutricionais ainda pouco exploradas cientificamente e comercialmente.
Ricardo de Morais Mendes, Ellen Pinto, Dayana Soares   +2 more
doaj   +3 more sources

Araçá (Psidium Cattleianum Sabine) ethanol extracts increase lifespan and alleviate oxidative stress in Caenorhabditis elegans

Journal of Agriculture and Food Research, 2023
Yellow- and red-colored berry varieties of araçá (Psidium cattleianum Sabine) ethanolic extracts have excellent antioxidant capacity in vitro and in vivo.
Liliana de Los Santos Moraes, Nathane Rosa Rodrigues, Ana Helena Dal Forno, Andréia Limana Tambara, Jean Ramos Boldori, Márcia Vizzotto, Andréia Quatrin, Tatiana Emanuelli, Cristiane Casagrande Denardin   +8 more
doaj   +1 more source

Bioactive compounds in baby foods for complementary feeding

Semina: Ciências Biológicas e da Saúde, 2021
Objetivo: verificar a presença de compostos bioativos em papas principais, recomendadas para alimentação complementar. Métodos: a amostra foi constituída por seis preparações de papas principais, escolhidas aleatoriamente, cujas receitas são encontradas
Camila Pizzano Fonseca, Fernanda A. Tamashiro, Veridiana Vera de Rosso, Patricia da Graça Leite Speridião   +3 more
doaj   +1 more source

Composição centesimal e bioativos no alho minimamente processado

Revista Principia, 2022
O alho (Allium sativum) apresenta propriedades condimentares com aroma e sabor característicos. Sua composição nutricional e compostos bioativos aumentam o interesse por essa hortaliça.
Franciélia de Oliveira da Silva, Charlene Maria de Alcântara, Ana Marinho do Nascimento, Jéssica Leite da Silva, Larissa Félix Macêdo, Franciscleudo Bezerra da Costa   +5 more
doaj   +1 more source