Results 21 to 30 of about 2,943 (163)

The Biological Role of Conoporins, Actinoporin-like Pore-Forming Toxins from Cone Snails [PDF]

open access: yesToxins
Cone snails are a large group of marine gastropods that produce a complex mixture of toxic compounds to hunt prey and defend against predators. The majority of the venom comprises small toxic peptides named conotoxins, which target membrane receptors. In
Matija Ruparčič   +5 more
doaj   +2 more sources

Venomics-Accelerated Cone Snail Venom Peptide Discovery. [PDF]

open access: yesInt J Mol Sci, 2018
Cone snail venoms are considered a treasure trove of bioactive peptides. Despite over 800 species of cone snails being known, each producing over 1000 venom peptides, only about 150 unique venom peptides are structurally and functionally characterized.
Himaya SWA, Lewis RJ.
europepmc   +5 more sources

Small Molecules in the Cone Snail Arsenal. [PDF]

open access: yesOrg Lett, 2015
Cone snails are renowned for producing peptide-based venom, containing conopeptides and conotoxins, to capture their prey. A novel small-molecule guanine derivative with unprecedented features, genuanine, was isolated from the venom of two cone snail species.
Neves JL   +6 more
europepmc   +4 more sources

Combined Proteotranscriptomic-Based Strategy to Discover Novel Antimicrobial Peptides from Cone Snails

open access: yesBiomedicines, 2021
Despite their impressive diversity and already broad therapeutic applications, cone snail venoms have received less attention as a natural source in the investigation of antimicrobial peptides than other venomous animals such as scorpions, spiders, or ...
Anicet Ebou   +4 more
doaj   +1 more source

Revision of the deep-water cone snail fauna from New Caledonia (Gastropoda, Conoidea)

open access: yesEuropean Journal of Taxonomy, 2023
The present work reviews the deep-water cone fauna of New Caledonia and its Economic Exclusive Zone. It is based on the material collected for more than 40 years by oceanographic expeditions in the deep waters surrounding New Caledonia, organized by the
Manuel J. Tenorio, Nicolas Puillandre
doaj   +1 more source

High-throughput prediction and characterization of antimicrobial peptides from multi-omics datasets of Chinese tubular cone snail (Conus betulinus)

open access: yesFrontiers in Marine Science, 2022
Individual cone snail (Conus sp.) contains thousands of bioactive peptides, but there are limited studies on its antimicrobial peptides (AMPs). Here, we investigated AMPs along with AMP-derived genes in the representative Chinese tubular cone snail (C ...
Ruihan Li   +16 more
doaj   +1 more source

Venomics Reveals a Non-Compartmentalised Venom Gland in the Early Diverged Vermivorous Conus distans

open access: yesToxins, 2022
The defensive use of cone snail venom is hypothesised to have first arisen in ancestral worm-hunting snails and later repurposed in a compartmentalised venom duct to facilitate the dietary shift to molluscivory and piscivory.
Jutty Rajan Prashanth   +3 more
doaj   +1 more source

High conopeptide diversity in Conus striatus: Revealed by integration of two transcriptome sequencing platforms

open access: yesFrontiers in Marine Science, 2022
Marine cone snail venoms represent a vast library of bioactive peptides with proven potential as research tools, drug leads, and therapeutics. In this study, a transcriptome library of four different organs, namely radular sheath, venom duct, venom gland,
Yanling Liao   +8 more
doaj   +1 more source

Recruitment of Glycosyl Hydrolase Proteins in a Cone Snail Venomous Arsenal: Further Insights into Biomolecular Features of Conus Venoms

open access: yesMarine Drugs, 2012
Cone snail venoms are considered an untapped reservoir of extremely diverse peptides, named conopeptides, displaying a wide array of pharmacological activities.
Philippe Favreau   +10 more
doaj   +1 more source

Microhabitats within Venomous Cone Snails Contain Diverse Actinobacteria [PDF]

open access: yesApplied and Environmental Microbiology, 2009
ABSTRACT Actinomycetes can be symbionts in diverse organisms, including both plants and animals. Some actinomycetes benefit their host by producing small molecule secondary metabolites; the resulting symbioses are often developmentally complex. Actinomycetes associated with three cone snails were studied.
Olivier, Peraud   +6 more
openaire   +2 more sources

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