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Ion Channel Toxins and Therapeutics: From Cone Snail Venoms to Ciguatera
Therapeutic Drug Monitoring, 2000Ion channels are intimately linked to all neurotransmission and neurotransmitter release processes, but in disease states often contribute adversely to disease pathology. The diversity and distribution of ion channel types and subtypes being uncovered through the use of molecular biology and toxin probes present an exciting opportunity for the ...
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PPIase is associated with the diversity of conotoxins from cone snail venom glands
Biochimie, 2015Cone snails are incredibly rich sources of bioactive conopeptides with potential for use in neuroscience research and novel drug development. In order to investigate the synthesis of diversified conopeptides in venom glands, the proteome and peptidome profiles of conus venom were analyzed using HPLC and mass spectrometry.
Lei, Wang +9 more
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The chemistry of snake venom and its medicinal potential
Nature Reviews Chemistry, 2022Ana Oliveira +2 more
exaly
Structural characterisation of defensive cone snail venom peptides
Toxicon, 2019David Wilson +3 more
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Causes and Consequences of Snake Venom Variation
Trends in Pharmacological Sciences, 2020Nicholas Casewell +2 more
exaly