The mitochondrial genome of the venomous cone snail Conus consors. [PDF]
PLoS ONE, 2012 Cone snails are venomous predatory marine neogastropods that belong to the species-rich superfamily of the Conoidea. So far, the mitochondrial genomes of two cone snail species (Conus textile and Conus borgesi) have been described, and these feed on ...
Age Brauer +9 more
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Predatory and Defensive Strategies in Cone Snails [PDF]
ToxinsCone snails are carnivorous marine animals that prey on fish (piscivorous), worms (vermivorous), or other mollusks (molluscivorous). They produce a complex venom mostly made of disulfide-rich conotoxins and conopeptides in a compartmentalized venom gland.
Zahrmina Ratibou +2 more
doaj +4 more sources
Neuronal Nicotinic Acetylcholine Receptor Modulators from Cone Snails [PDF]
Marine Drugs, 2018 Marine cone snails are a large family of gastropods that have evolved highly potent venoms for predation and defense. The cone snail venom has exceptional molecular diversity in neuropharmacologically active compounds, targeting a range of receptors, ion
Nikita Abraham, Richard J. Lewis
doaj +6 more sources
Combined Proteotranscriptomic-Based Strategy to Discover Novel Antimicrobial Peptides from Cone Snails [PDF]
Biomedicines, 2021 Despite their impressive diversity and already broad therapeutic applications, cone snail venoms have received less attention as a natural source in the investigation of antimicrobial peptides than other venomous animals such as scorpions, spiders, or ...
Anicet Ebou +4 more
doaj +2 more sources
Glowing seashells: diversity of fossilized coloration patterns on coral reef-associated cone snail (Gastropoda: Conidae) shells from the Neogene of the Dominican Republic. [PDF]
PLoS ONE, 2015 The biology of modern Conidae (cone snails)--which includes the hyperdiverse genus Conus--has been intensively studied, but the fossil record of the clade remains poorly understood, particularly within an evolutionary framework.
Jonathan R Hendricks
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Diversity and Evolutionary Analysis of Venom Insulin Derived from Cone Snails [PDF]
ToxinsCone snails possess a diverse array of novel peptide toxins, which selectively target ion channels and receptors in the nervous and cardiovascular systems. These numerous novel peptide toxins are a valuable resource for future marine drug development. In
Qiqi Guo +6 more
doaj +2 more sources
Cone Snails: A Big Store of Conotoxins for Novel Drug Discovery [PDF]
Toxins, 2017 Marine drugs have developed rapidly in recent decades. Cone snails, a group of more than 700 species, have always been one of the focuses for new drug discovery.
Bingmiao Gao +5 more
doaj +2 more sources
High-Throughput Identification and Analysis of Novel Conotoxins from Three Vermivorous Cone Snails by Transcriptome Sequencing [PDF]
Marine Drugs, 2019 The venom of each Conus species consists of a diverse array of neurophysiologically active peptides, which are mostly unique to the examined species. In this study, we performed high-throughput transcriptome sequencing to extract and analyze putative ...
Ge Yao +7 more
doaj +2 more sources
Comparative Venomics of C. flavidus and C. frigidus and Closely Related Vermivorous Cone Snails [PDF]
Marine Drugs, 2022 Cone snail venom biodiversity reflects dietary preference and predatory and defensive envenomation strategies across the ≈900 species of Conidae. To better understand the mechanisms of adaptive radiations in closely related species, we investigated the ...
S. W. A. Himaya +3 more
doaj +2 more sources
The Biological Role of Conoporins, Actinoporin-like Pore-Forming Toxins from Cone Snails [PDF]
ToxinsCone snails are a large group of marine gastropods that produce a complex mixture of toxic compounds to hunt prey and defend against predators. The majority of the venom comprises small toxic peptides named conotoxins, which target membrane receptors. In
Matija Ruparčič +5 more
doaj +2 more sources