Results 41 to 50 of about 2,235 (121)

The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea

open access: yesMarine Drugs, 2017
The marine cone snail Conus gloriamaris is an iconic species. For over two centuries, its shell was one of the most prized and valuable natural history objects in the world.
Samuel D. Robinson   +6 more
doaj   +1 more source

The E‐cadherin‐Wnt‐mir‐994 Axis Repurposes a Cadherin Switch for Niche Robustness and Germline Stem Cell Maintenance

open access: yesCell Proliferation, EarlyView.
In the Drosophila ovarian niche, an E‐cadherin‐to‐N‐cadherin switch, mediated by Wnt‐mir‐994 signalling, is repurposed to ensure niche resilience. This compensatory mechanism maintains niche integrity and stem cell support upon E‐cadherin loss, revealing a robustness circuit.
Renjun Tu   +6 more
wiley   +1 more source

Conotoxins: Therapeutic Potential and Application

open access: yesMarine Drugs, 2006
The pharmacological variety of conotoxins, diverse peptides found in the venoms of marine cone snails, is well recognized. Venoms from each of the estimated 500 species of cone snails contain 50 to 200 distinct biologically active peptides.
Richard T. Layer, J. Michael McIntosh
doaj   +1 more source

Unveiling Gut Homeostasis Disruption in Sepsis: Towards an Integrated Mechanistic and Translational Roadmap

open access: yesCell Proliferation, EarlyView.
Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao   +7 more
wiley   +1 more source

From biology to biotechnology: Host‐regulation factors from parasitoid wasps are a source of bioactive molecules with translational potential

open access: yesInsect Molecular Biology, EarlyView.
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto   +2 more
wiley   +1 more source

Transcriptomic-Proteomic Correlation in the Predation-Evoked Venom of the Cone Snail, Conus imperialis

open access: yesMarine Drugs, 2019
Individual variation in animal venom has been linked to geographical location, feeding habit, season, size, and gender. Uniquely, cone snails possess the remarkable ability to change venom composition in response to predatory or defensive stimuli.
Ai-Hua Jin   +6 more
doaj   +1 more source

Colonisation History of Freshwater Snails Across the Atlantic and Mediterranean Islands: Insights From Mercuria (Littorinimorpha, Hydrobiidae)

open access: yesZoologica Scripta, EarlyView.
ABSTRACT Islands harbour unique biodiversity, and depending on their geological origin, they have fundamentally different colonisation histories: continental islands may contain relict faunas shaped by vicariance and sporadic gene flow, whereas oceanic islands must have been colonised across open seas, often through long‐distance dispersal events ...
Jonathan P. Miller   +3 more
wiley   +1 more source

Mining Invertebrate Natural Products for Future Therapeutic Treasure

open access: yesNatural Product Communications, 2011
This review focuses on biologically active entities from invertebrate sources, especially snails. The reader will encounter several categories of compounds from snails including glycosaminoglycans, peptides, proteins (glycoproteins), and enzymes which ...
Youmie Park
doaj   +1 more source

Dynamic Current Routing in Conductive Liquid Crystal Elastomers for Complex Deformation Actuators

open access: yesAdvanced Materials Technologies, Volume 11, Issue 12, 18 June 2026.
This work introduces a novel actuation control strategy in which electrical stimulation generates localized Joule heating in conductive liquid crystal elastomer (LCE) surfaces, enabling complex 3D deformations from a single homogeneous surface without preprogramming.
Gloria PouWai Lei   +2 more
wiley   +1 more source

Diverse Cone-Snail Species Harbor Closely Related Streptomyces Species with Conserved Chemical and Genetic Profiles, Including Polycyclic Tetramic Acid Macrolactams

open access: yesFrontiers in Microbiology, 2017
Streptomyces are Gram-positive bacteria that occupy diverse ecological niches including host-associations with animals and plants. Members of this genus are known for their overwhelming repertoire of natural products, which has been exploited for almost ...
Michelle Quezada   +6 more
doaj   +1 more source

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