Results 31 to 40 of about 225,321 (188)

Venom variation during prey capture by the cone snail, Conus textile. [PDF]

open access: yesPLoS ONE, 2014
Observations of the mollusc-hunting cone snail Conus textile during feeding reveal that prey are often stung multiple times in succession. While studies on the venom peptides injected by fish-hunting cone snails have become common, these approaches have ...
Cecilia A Prator   +2 more
doaj   +1 more source

Cone snail species off the Brazilian coast and their venoms: a review and update

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2023
The genus Conus includes over 900 species of marine invertebrates known as cone snails, whose venoms are among the most powerful described so far.
Helena B. Fiorotti   +3 more
doaj   +1 more source

Coordinated adaptations define the ontogenetic shift from worm- to fish-hunting in a venomous cone snail

open access: yesNature Communications, 2023
Marine cone snails have attracted researchers from all disciplines but early life stages have received limited attention due to difficulties accessing or rearing juvenile specimens.
Aymeric Rogalski   +2 more
doaj   +1 more source

From venom peptides to a potential diabetes treatment

open access: yeseLife, 2019
Cone snails have evolved a variety of insulin-like molecules that may help with the development of better treatments for diabetes.
Jiří Jiráček, Lenka Žáková
doaj   +1 more source

A toxin-based approach to neuropeptide and peptide hormone discovery

open access: yesFrontiers in Molecular Neuroscience, 2023
Peptide hormones and neuropeptides form a diverse class of bioactive secreted molecules that control essential processes in animals. Despite breakthroughs in peptide discovery, many signaling peptides remain undiscovered.
Thomas Lund Koch   +10 more
doaj   +1 more source

Fish-hunting cone snail venoms are a rich source of minimized ligands of the vertebrate insulin receptor

open access: yeseLife, 2019
The fish-hunting marine cone snail Conus geographus uses a specialized venom insulin to induce hypoglycemic shock in its prey. We recently showed that this venom insulin, Con-Ins G1, has unique characteristics relevant to the design of new insulin ...
Peter Ahorukomeye   +13 more
doaj   +1 more source

Accelerated proteomic visualization of individual predatory venoms of Conus purpurascens reveals separately evolved predation-evoked venom cabals

open access: yesScientific Reports, 2018
Cone snail venoms have separately evolved for predation and defense. Despite remarkable inter- and intra-species variability, defined sets of synergistic venom peptides (cabals) are considered essential for prey capture by cone snails.
S. W. A. Himaya   +2 more
doaj   +1 more source

Mitochondrial genome sequencing of a vermivorous cone snail Conus quercinus supports the correlative analysis between phylogenetic relationships and dietary types of Conus species.

open access: yesPLoS ONE, 2018
Complete mitochondrial genome (mitogenome) sequence of a worm-hunting cone snail, Conus quercinus, was reported in this study. Its mitogenome, the longest one (16,460 bp) among reported Conus specie, is composed of 13 protein-coding genes (PCGs), 22 ...
Bingmiao Gao   +4 more
doaj   +1 more source

Chemical Synthesis and NMR Solution Structure of Conotoxin GXIA from Conus geographus

open access: yesMarine Drugs, 2021
Conotoxins are disulfide-rich peptides found in the venom of cone snails. Due to their exquisite potency and high selectivity for a wide range of voltage and ligand gated ion channels they are attractive drug leads in neuropharmacology.
David A. Armstrong   +5 more
doaj   +1 more source

Comparative Venomics of the Cryptic Cone Snail Species Virroconus ebraeus and Virroconus judaeus

open access: yesMarine Drugs, 2022
The venom duct transcriptomes and proteomes of the cryptic cone snail species Virroconus ebraeus and Virroconus judaeus were obtained and compared.
José Ramón Pardos-Blas   +3 more
doaj   +1 more source

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