Results 11 to 20 of about 9,392 (157)

Conopeptides from Cape Verde Conus crotchii [PDF]

Marine Drugs, 2013
Marine Cone snails of the genus Conus contain complex peptide toxins in their venom. Living in tropical habitats, they usually use the powerful venom for self-defense and prey capture.
Agostinho Antunes, Vitor Vasconcelos, Hugo Osório, Jorge Neves, Alexandre Campos   +4 more
doaj   +3 more sources

Venomous Secretions from Marine Snails of the Terebridae Family Target Acetylcholine Receptors [PDF]

Toxins, 2013
Venoms from cone snails (Conidae) have been extensively studied during the last decades, but those from other members of the suborder Toxoglossa, such as of Terebridae and Turridae superfamilies attracted less interest so far. Here, we report the effects
Cora Wunder, Dietrich Mebs, Jan Tytgat, Steve Peigneur, Annette Nicke, Alexander Kurz, Christian Melaun, Yvonne Kendel, Silke Kauferstein   +8 more
doaj   +4 more sources

Conkazal-M1 from the MKAVA family of conotoxins: A dual-function protease inhibitor and neuroactive peptide. [PDF]

Protein Sci
Abstract Marine cone snails produce a diverse array of bioactive peptides, known as conotoxins, in their venom. Given their high target potency and specificity, conotoxins are attractive compounds for the development of precision research tools and pharmacological agents.
Hackney CM, Koch TL, Ryding NL, Rogalski A, Chase K, Giglio ML, Espino SS, Acyatan ZG, Watkins M, Olivera BM, Safavi-Hemami H, Teilum K, Ellgaard L.   +12 more
europepmc   +2 more sources

Structural and Functional Analyses of Cone Snail Toxins

Marine Drugs, 2019
Cone snails are marine gastropod mollusks with one of the most powerful venoms in nature. The toxins, named conotoxins, must act quickly on the cone snails´ prey due to the fact that snails are extremely slow, reducing their hunting capability ...
Harry Morales Duque, Simoni Campos Dias, Octávio Luiz Franco   +2 more
doaj   +3 more sources

Phylogenetic relationships of cone snails endemic to Cabo Verde based on mitochondrial genomes [PDF]

BMC Evolutionary Biology, 2017
Background Due to their great species and ecological diversity as well as their capacity to produce hundreds of different toxins, cone snails are of interest to evolutionary biologists, pharmacologists and amateur naturalists alike.
Samuel Abalde, Manuel J. Tenorio, Carlos M. L. Afonso, Juan E. Uribe, Ana M. Echeverry, Rafael Zardoya   +5 more
doaj   +2 more sources

Somatostatin venom analogs evolved by fish-hunting cone snails: From prey capture behavior to identifying drug leads. [PDF]

Sci Adv, 2022
Ramiro IBL, Bjørn-Yoshimoto WE, Imperial JS, Gajewiak J, Salcedo PF, Watkins M, Taylor D, Resager W, Ueberheide B, Bräuner-Osborne H, Whitby FG, Hill CP, Martin LF, Patwardhan A, Concepcion GP, Olivera BM, Safavi-Hemami H.   +16 more
europepmc   +2 more sources

Non-Peptidic Small Molecule Components from Cone Snail Venoms

Frontiers in Pharmacology, 2021
Venomous molluscs (Superfamily Conoidea) comprise a substantial fraction of tropical marine biodiversity (>15,000 species). Prior characterization of cone snail venoms established that bioactive venom components used to capture prey, defend against ...
Zhenjian Lin, Joshua P. Torres, Maren Watkins, Noemi Paguigan, Changshan Niu, Julita S. Imperial, Jortan Tun, Helena Safavi-Hemami, Helena Safavi-Hemami, Rocio K. Finol-Urdaneta, Jorge L. B. Neves, Samuel Espino, Manju Karthikeyan, Baldomero M. Olivera, Eric W. Schmidt   +14 more
doaj   +1 more source

Specialized insulin is used for chemical warfare by fish-hunting cone snails. [PDF]

Proc Natl Acad Sci U S A, 2015
Safavi-Hemami H, Gajewiak J, Karanth S, Robinson SD, Ueberheide B, Douglass AD, Schlegel A, Imperial JS, Watkins M, Bandyopadhyay PK, Yandell M, Li Q, Purcell AW, Norton RS, Ellgaard L, Olivera BM.   +15 more
europepmc   +2 more sources

Molecular phylogeny and evolution of the cone snails (Gastropoda, Conoidea). [PDF]

Mol Phylogenet Evol, 2014
Puillandre N, Bouchet P, Duda TF, Kauferstein S, Kohn AJ, Olivera BM, Watkins M, Meyer C.   +7 more
europepmc   +2 more sources

Complete mitochondrial genome of Conus lischkeanus Weinkauff, 1875 (Neogastropoda, Conidae) and phylogenetic implications of the evolutionary diversification of dietary types of Conus species [PDF]

ZooKeys, 2022
The family Conidae, commonly known as cone snails, is one of the most intriguing gastropod groups owing to their diverse array of feeding behaviors (diets) and toxin peptides (conotoxins).
Yucheol Lee, Joong-Ki Park
doaj   +3 more sources