Results 31 to 40 of about 9,402 (207)

Dietary breadth is positively correlated with venom complexity in cone snails. [PDF]

BMC Genomics, 2016
AbstractAlthough diet is believed to be a major factor underlying the evolution of venom, few comparative studies examine both venom composition and diet across a radiation of venomous species. Cone snails within the family, Conidae, comprise more than 700 species of carnivorous marine snails that capture their prey by using a cocktail of venomous ...
Phuong MA, Mahardika GN, Alfaro ME.
europepmc   +6 more sources

Venom Insulins of Cone Snails Diversify Rapidly and Track Prey Taxa. [PDF]

Mol Biol Evol, 2016
A specialized insulin was recently found in the venom of a fish-hunting cone snail, Conus geographus Here we show that many worm-hunting and snail-hunting cones also express venom insulins, and that this novel gene family has diversified explosively.
Safavi-Hemami H, Lu A, Li Q, Fedosov AE, Biggs J, Showers Corneli P, Seger J, Yandell M, Olivera BM.   +8 more
europepmc   +6 more sources

Molecular phylogeny and evolution of the cone snails (Gastropoda, Conoidea). [PDF]

Mol Phylogenet Evol, 2014
We present a large-scale molecular phylogeny that includes 320 of the 761 recognized valid species of the cone snails (Conus), one of the most diverse groups of marine molluscs, based on three mitochondrial genes (COI, 16S rDNA and 12S rDNA). This is the first phylogeny of the taxon to employ concatenated sequences of several genes, and it includes ...
Puillandre N, Bouchet P, Duda TF, Kauferstein S, Kohn AJ, Olivera BM, Watkins M, Meyer C.   +7 more
europepmc   +7 more sources

Using Marine Snails to Teach Biogeography and Macroevolution: The Role of Larvae and Dispersal Ability in the Evolution and Persistence of Species [PDF]

, 2012
While some marine animals are capable of traveling great distances, many have limited mobility as adults and spend the majority of their lifetimes in a small geographical area or may even be cemented to a single place.
Hendricks, Jonathan R
core   +3 more sources

Fish-hunting cone snail venoms are a rich source of minimized ligands of the vertebrate insulin receptor

eLife, 2019
The fish-hunting marine cone snail Conus geographus uses a specialized venom insulin to induce hypoglycemic shock in its prey. We recently showed that this venom insulin, Con-Ins G1, has unique characteristics relevant to the design of new insulin ...
Peter Ahorukomeye, Maria M Disotuar, Joanna Gajewiak, Santhosh Karanth, Maren Watkins, Samuel D Robinson, Paula Flórez Salcedo, Nicholas A Smith, Brian J Smith, Amnon Schlegel, Briony E Forbes, Baldomero Olivera, Danny Hung-Chieh Chou, Helena Safavi-Hemami   +13 more
doaj   +1 more source

Accelerated proteomic visualization of individual predatory venoms of Conus purpurascens reveals separately evolved predation-evoked venom cabals

Scientific Reports, 2018
Cone snail venoms have separately evolved for predation and defense. Despite remarkable inter- and intra-species variability, defined sets of synergistic venom peptides (cabals) are considered essential for prey capture by cone snails.
S. W. A. Himaya, Frank Marí, Richard J. Lewis   +2 more
doaj   +1 more source

Chemical Synthesis and NMR Solution Structure of Conotoxin GXIA from Conus geographus

Marine Drugs, 2021
Conotoxins are disulfide-rich peptides found in the venom of cone snails. Due to their exquisite potency and high selectivity for a wide range of voltage and ligand gated ion channels they are attractive drug leads in neuropharmacology.
David A. Armstrong, Ai-Hua Jin, Nayara Braga Emidio, Richard J. Lewis, Paul F. Alewood, K. Johan Rosengren   +5 more
doaj   +1 more source

Mitochondrial genome sequencing of a vermivorous cone snail Conus quercinus supports the correlative analysis between phylogenetic relationships and dietary types of Conus species.

PLoS ONE, 2018
Complete mitochondrial genome (mitogenome) sequence of a worm-hunting cone snail, Conus quercinus, was reported in this study. Its mitogenome, the longest one (16,460 bp) among reported Conus specie, is composed of 13 protein-coding genes (PCGs), 22 ...
Bingmiao Gao, Chao Peng, Qin Chen, Junqing Zhang, Qiong Shi   +4 more
doaj   +1 more source

Point of Care Diagnosis of Multiple Schistosome Parasites: Species-specific DNA Detection in Urine by Loop-mediated Isothermal Amplification (LAMP) [PDF]

, 2017
Schistosomes are easily transmitted and high chance of repeat infection, so if control strategies based on targeted mass drug administration (MDA) are to succeed it is essential to have a test that is sensitive, accurate and simple to use.
Anyan, William K., Bosompem, Kwabena M., Lodh, Nilanjan, Mikita, Kei, Otchere, Joseph, Quartey, Joseph K., Shiff, Clive J.   +6 more
core   +2 more sources

Toxins from cone snails: properties, applications and biotechnological production [PDF]

Applied Microbiology and Biotechnology, 2008
AbstractCone snails are marine predators that use venoms to immobilize their prey. The venoms of these mollusks contain a cocktail of peptides that mainly target different voltage- and ligand-gated ion channels. Typically, conopeptides consist of ten to 30 amino acids but conopeptides with more than 60 amino acids have also been described. Due to their
Becker, S., Terlau, H.
openaire   +3 more sources