Results 41 to 50 of about 9,402 (207)

Novel conopeptides of the I-superfamily occur in several clades of cone snails [PDF]

open access: yes, 2004
The I-superfamily of conotoxins represents a new class of peptides in the venom of some Conus species. These toxins are characterized by four disulfide bridges and inhibit or modify ion channels of nerve cells.
Huys, I.   +5 more
core   +1 more source

Integrating Venom Peptide Libraries Into a Phylogenetic and Broader Biological Framework

open access: yesFrontiers in Molecular Biosciences, 2022
The venomous marine snails are conventionally divided into three groups, the cone snails (family Conidae), the auger snails (family Terebridae) and the turrids (formerly all assigned to a single family, Turridae).
Kevin Chase   +5 more
doaj   +1 more source

Recruitment of Glycosyl Hydrolase Proteins in a Cone Snail Venomous Arsenal: Further Insights into Biomolecular Features of Conus Venoms

open access: yesMarine Drugs, 2012
Cone snail venoms are considered an untapped reservoir of extremely diverse peptides, named conopeptides, displaying a wide array of pharmacological activities.
Philippe Favreau   +10 more
doaj   +1 more source

Curses or Cures: A Review of the Numerous Benefits Versus the Biosecurity Concerns of Conotoxin Research

open access: yesBiomedicines, 2020
Conotoxins form a diverse group of peptide toxins found in the venom of predatory marine cone snails. Decades of conotoxin research have provided numerous measurable scientific and societal benefits.
Walden E. Bjørn-Yoshimoto   +6 more
doaj   +1 more source

Comparative Venomics of the Cryptic Cone Snail Species Virroconus ebraeus and Virroconus judaeus

open access: yesMarine Drugs, 2022
The venom duct transcriptomes and proteomes of the cryptic cone snail species Virroconus ebraeus and Virroconus judaeus were obtained and compared.
José Ramón Pardos-Blas   +3 more
doaj   +1 more source

Alpha9 nicotinic acetylcholine receptors and the treatment of pain [PDF]

open access: yes, 2009
Chronic pain is a vexing worldwide problem that causes substantial disability and consumes significant medical resources. Although there are numerous analgesic medications, these work through a small set of molecular mechanisms.
Absalom, Nathan   +4 more
core   +1 more source

Toxins in Drug Discovery and Pharmacology

open access: yesToxins, 2018
Venoms from marine and terrestrial animals (cone snails, scorpions, spiders, snakes, centipedes, cnidarian, etc.) can be seen as an untapped cocktail of biologically active compounds, being increasingly recognized as a new emerging source of peptide ...
Steve Peigneur, Jan Tytgat
doaj   +1 more source

Mitogenomic phylogeny of cone snails endemic to Senegal

open access: yesMolecular Phylogenetics and Evolution, 2017
Cone snails attain in Senegal one of their highest peaks of species diversity throughout the continental coast of Western Africa. A total of 15 endemic species have been described, all placed in the genus Lautoconus. While there is ample data regarding the morphology of the shell and the radular tooth of these species, virtually nothing is known ...
Abalde, Samuel   +3 more
openaire   +4 more sources

Hydrobiidae on North Uist [PDF]

open access: yes, 2014
One of the problems of working on lochs that are slightly saline is a group of tiny (1-4mm) molluscs called mudsnails (Hydrobiidae). The rarest of these, Hydrobia acuta neglecta, was first identified in the UK in the Uists.
Chambers, S   +3 more
core   +2 more sources

Beyond Conus: Phylogenetic relationships of Conidae based on complete mitochondrial genomes [PDF]

open access: yes, 2017
Understanding how the extraordinary taxonomic and ecological diversity of cone snails (Caenogastropoda: Conidae) evolved requires a statistically robust phylogenetic framework, which thus far is not available. While recent molecular phylogenies have been
Puillandre, Nicolas   +2 more
core   +2 more sources

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