Results 81 to 90 of about 5,562,313 (185)
Roles of gap junctions, connexins and pannexins in epilepsy
Frontiers in Physiology, 2014 Enhanced gap junctional communication (GJC) between neurons is considered a major factor underlying the neuronal synchrony driving seizure activity. In addition, the hippocampal sharp wave ripple complexes, associated with learning and seizures, are ...
Shanthini eMylvaganam +3 more
doaj +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Notoginsenoside‐Fa (Noto‐Fa) is an emerging active compound derived from notoginseng with promise in treating cardiovascular diseases. The development of cardiovascular diseases is intricately linked to the damage of vascular endothelium and it is widely acknowledged that numerous chronic inflammation pathways, especially the ...
Xiao‐Ying Yu +9 more
wiley +1 more source
Regulation of connexin expression [PDF]
, 2005 Gap junctions contain cell–cell communicating channels that consist of multimeric proteins called connexins and mediate the exchange of low-molecular-weight metabolites and ions between contacting cells.
Oyamada, Masahito +5 more
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British Journal of Pharmacology, EarlyView.Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, but their efficacy continues to be limited by immune‐related adverse events. Among these, ICI‐induced cardiac arrhythmias are increasingly recognised as a major adverse reaction, encompassing a broad spectrum of clinical phenotypes, including conduction blocks, atrial fibrillation and
Anand R. Ramalingam +3 more
wiley +1 more source
Connexin-32 and Connexin-43 Immunoreactivity in Rodent Taste Buds [PDF]
, 2012 Studies indicate that ATP is one of the primary neurotransmitters in taste transduction. ATP release occurs from taste cells via specific hemichannels such as pannexin/connexin hemichannels (Huang et al., 2007; Romanov et al., 2007).
Bond, Amanda E.
core +1 more source
Cell Transplantation, 2005 The mechanisms of donor hepatocyte integration into recipient liver are not fully understood. We investigated mechanisms of both the integration and interaction of transplanted hepatocytes with host liver cells as well as the repopulation of the host ...
Sarah Koenig +4 more
doaj +1 more source
The Modulating Role of Vitamin E Against Potassium Dichromate's Cardiotoxicity in Adult Albino Rat [PDF]
The Egyptian Journal of HistologyIntroduction: One extremely hazardous inorganic chemical reagent is potassium dichromate (PD). Despite its genotoxic, immunotoxic, and carcinogenic effects, it is nevertheless frequently employed in industrial and laboratory settings.
Walaa Farag, Esraa Mohamed
doaj +1 more source
The FEBS Journal, EarlyView.Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi +12 more
wiley +1 more source
The FEBS Journal, EarlyView.Astrocytic gap junctions formed by connexin43 (Cx43) help maintain brain homeostasis. After mild traumatic brain injury (TBI), total cortical Cx43 increases and redistributes toward a soluble, non‐junctional pool with elevated hemichannel activity and increased phosphorylation at serine 368 (pCx43S368).
Carmen Muñoz‐Ballester +11 more
wiley +1 more source
Бюллетень сибирской медицины, 2014 The aim of this research was to assess a role of connexin 43 (Cx43) and associated molecule CD38 in the regulation of cell-cell interactions in the neurovascular unit (NVU) in vitro in physiological conditions and in hypoxia.Materials and methods.
A. V. Morgun +4 more
doaj +1 more source