Results 31 to 40 of about 14,893 (256)
FROM PHYSIOLOGICAL TO NEOPLASTIC TRANSFORMATION: THE CRITICAL ROLES OF CONNEXINS AND WT1 [PDF]
Euromediterranean Biomedical Journal, 2022 Glioblastoma and soft tissue sarcomas are tumors characterized by poor prognosis, low overall survival and critical hallmarks that allow such tumors to evade homeostatic controlling mechanisms.
Giovanni Li Volti
doaj +1 more source
Mitochondrial Connexins and Mitochondrial Contact Sites with Gap Junction Structure
, 2023 Mitochondria contain connexins, a family of proteins that is known to form gap junction channels. Connexins are synthesized in the endoplasmic reticulum and oligomerized in the Golgi to form hemichannels.
Sharon C. Francis +6 more
core +1 more source
Connexin’s Connection in Breast Cancer Growth and Progression
International Journal of Cell Biology, 2016 Gap junctions are cell-to-cell junctions that are located in the basolateral surface of two adjoining cells. A gap junction channel is composed of a family of proteins called connexins.
Debarshi Banerjee
doaj +1 more source
Connexin Channels, Connexin Mimetic Peptides and ATP Release [PDF]
Cell Communication & Adhesion, 2003 Connexin hemichannels, that is, half gap junction channels (not connecting cells), have been implicated in the release of various messengers such as ATP and glutamate. We used connexin mimetic peptides, which are, small peptides mimicking a sequence on the connexin subunit, to investigate hemichannel functioning in endothelial cell lines.
Leybaert, L. +5 more
openaire +5 more sources
Gap junction protein connexin43 exacerbates lung vascular permeability. [PDF]
PLoS ONE, 2014 Increased vascular permeability causes pulmonary edema that impairs arterial oxygenation and thus contributes to morbidity and mortality associated with Acute Respiratory Distress Syndrome and sepsis.
James J O'Donnell +3 more
doaj +1 more source
Role of connexins and pannexins in cardiovascular physiology [PDF]
, 2021 Connexins and pannexins form connexons, pannexons and membrane channels, which are critically involved in many aspects of cardiovascular physiology.
Duffy, Heather +2 more
core
Connexins: Sensors of epidermal integrity that are therapeutic targets [PDF]
, 2014 Gap junction proteins (connexins) are differentially expressed throughout the multiple layers of the epidermis. A variety of skin conditions arise with aberrant connexin expression or function and suggest that maintaining the epidermal gap junction ...
Wright, Catherine S +8 more
core +1 more source
Connexin43 in Post-Surgical Peritoneal Adhesion Formation
Life, 2022 Objective: Post-surgical peritoneal adhesions are a serious problem for the quality of life and fertility. Yet there are no effective ways of preventing their occurrence.
Jia Wang Chua +5 more
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Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2021 Background: The occurrence of Cutaneous Adverse Drug Reactions (CADRs) is relatively rare but can be fatal when causing organ failure, especially in the liver. The supporting examinations to determine liver injury are aspartate aminotransferase (AST) and
Dyah Ayu Mira Oktarina +2 more
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Connexin Mutants and Cataracts [PDF]
Frontiers in Pharmacology, 2013 The lens is a multicellular, but avascular tissue that must stay transparent to allow normal transmission of light and focusing of it on the retina. Damage to lens cells and/or proteins can cause cataracts, opacities that disrupt these processes.
Beyer, Eric C. +2 more
openaire +3 more sources