Results 11 to 20 of about 38,435 (285)
Cardiology Research and Practice, 2012 Cell-to-cell interactions via gap junctional communication and connexon hemichannels are involved in the pathogenesis of diabetes. Gap junctions are highly specialized transmembrane structures that are formed by connexon hemichannels, which are further ...
Josephine A. Wright +2 more
doaj +3 more sources
Coordination of innate immune responses by connexins [PDF]
Frontiers in ImmunologyInnate immunity comprises intricate cellular and tissue responses critical for host defense and tissue homeostasis. Intercellular communication is central to these responses and significantly influences infection, inflammatory disorders, and cancer ...
Qirou Wu +4 more
doaj +2 more sources
The role of connexins in wound healing and repair: novel therapeutic approaches
Frontiers in Physiology, 2016 Gap junctions are intercellular proteins responsible for mediating both electrical and biochemical coupling through the exchange of ions, second messengers and small metabolites.
Jeremy Wong +7 more
doaj +2 more sources
Reduced expression of multiple gap junction proteins is a feature of cervical dysplasia [PDF]
Molecular Cancer, 2005 Cervical dysplasia is a premalignant lesion associated with human papillomavirus (HPV) infection which, over time, can turn cancerous. Previous studies have indicated that loss of gap junctions may be a feature of cervical cancer and premalignant ...
Edward Mike +3 more
doaj +3 more sources
Connexins and Aging-Associated Respiratory Disorders: The Role in Intercellular Communications [PDF]
BiomedicinesThis article reviews the contemporary understanding of the functional role of connexins in intercellular communications, their involvement in maintaining cellular and tissue homeostasis, and in aging-associated respiratory disease pathogenesis. Connexins
Tatiana Zubareva +7 more
doaj +2 more sources
Connexins and pannexins in liver damage [PDF]
EXCLI Journal : Experimental and Clinical Sciences, 2016 Connexins and pannexins are key players in the control of cellular communication and thus in the maintenance of tissue homeostasis. Inherent to this function these proteins are frequently involved in pathological processes.
Cogliati, Bruno +7 more
core +2 more sources
Therapeutic strategies targeting connexins
Nature Reviews Drug Discovery, 2018 Dale W Laird, Paul D Lampe
exaly +2 more sources
Frontiers in Cellular Neuroscience, 2023 Neural stem cells (NSCs) persist in specific brain germinative niches and sustain neurogenesis throughout life in adult mammals. In addition to the two major stem cell niches in the subventricular zone and the hippocampal dentate gyrus, the area postrema
Cyrine Ben Dhaou +8 more
doaj +1 more source
Connexins in the Heart: Regulation, Function and Involvement in Cardiac Disease
International Journal of Molecular Sciences, 2021 Connexins are a family of transmembrane proteins that play a key role in cardiac physiology. Gap junctional channels put into contact the cytoplasms of connected cardiomyocytes, allowing the existence of electrical coupling.
A. Rodríguez-Sinovas +4 more
semanticscholar +1 more source
Connexins and their channels in inflammation
Critical Reviews in Biochemistry and Molecular Biology, 2016 Joost Willebrords +2 more
exaly +2 more sources