Cuproptosis, the current form of regulated cell death characterized by copper overload, oligomerization of lipoacylated proteins, and loss of Fe–S cluster proteins, has been proposed to function closely with human diseases, including cancer.
Chuang Wei, Qinrui Fu
doaj +1 more source
Editorial: Molecular and multi-omic approaches in understanding cancer biology and anticancer therapies: current perspectives and new challenges [PDF]
Peer ...
A. Abdel-Wahab, Basel +2 more
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Cuproptosis-related lncRNAs potentially predict prognosis and therapy sensitivity of breast cancer
Background: Cuproptosis-related lncRNAs regulate the biological functions of various cancers. However, the role of cuproptosis-related lncRNAs in breast cancer remains unclear.
Xiwen Wu +3 more
doaj +1 more source
Background: Pancreatic ductal adenocarcinoma (PDAC) is the most prevalent subtype of pancreatic cancer and one of the most malignant tumors worldwide. Due to the heterogeneity of its genomics and proteomics, the prognosis of PDAC remains disappointing ...
Yusheng Chen +12 more
doaj +1 more source
Cuproptosis is a novel form of copper‐induced programmed cell death. Here, we investigate the role of cuproptosis‐related genes in head and neck squamous cell carcinoma (HNSCC), and the correlations between cuproptosis‐related genes and tumor ...
Zhangwei Hu, Wenbin Lei, Weiping Wen
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The value of cuproptosis-related differential genes in guiding prognosis and immune status in patients with skin cutaneous melanoma [PDF]
Background: Skin cutaneous melanoma (SKCM) is one of the most common cutaneous malignancies, which incidence is increasing. Cuproptosis is a new type of programming cell death recently reported, which may affect the progression of SKCM.Method: The mRNA ...
Chufeng Jiang +4 more
core +1 more source
Cuproptosis, a newly identified form of programmed cell death, plays vital roles in tumorigenesis. However, the interconnectivity of cuproptosis and ferroptosis is poorly understood.
Yefeng Shen +6 more
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Prognostic value and immune infiltration analyses of cuproptosis-related genes in hepatocellular carcinoma [PDF]
The role of cuproptosis, a newly discovered form of programmed cell death, remains poorly understood in hepatocellular carcinoma (HCC). This study was aimed at constructing a novel cuproptosis model for analyzing the clinical features, mutation ...
Bin Liu +10 more
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Cuproptosis-related gene FDX1 as a prognostic biomarker for kidney renal clear cell carcinoma correlates with immune checkpoints and immune cell infiltration [PDF]
Background: Kidney renal clear cell carcinoma (KIRC) is not sensitive to radiotherapy and chemotherapy, and only some KIRC patients can benefit from immunotherapy and targeted therapy.
Haixin Chen +3 more
core +1 more source
Identification of a prognostic cuproptosis-related signature in hepatocellular carcinoma
Background Cuproptosis is a new type of copper-induced cell death that is characterized by the aggregation of lipoylated tricarboxylic acid (TCA) cycle proteins. However, its role in hepatocellular carcinoma (HCC) remains unclear.
Yuqiao Chen +6 more
doaj +1 more source

