Results 31 to 40 of about 7,425 (214)
Current Oncology, 2023 Background: Pancreatic ductal adenocarcinoma (PDAC) is the most prevalent subtype of pancreatic cancer and one of the most malignant tumors worldwide. Due to the heterogeneity of its genomics and proteomics, the prognosis of PDAC remains disappointing ...
Yusheng Chen +12 more
doaj +1 more source
Prognostic value and immune infiltration analyses of cuproptosis-related genes in hepatocellular carcinoma [PDF]
, 2023 The role of cuproptosis, a newly discovered form of programmed cell death, remains poorly understood in hepatocellular carcinoma (HCC). This study was aimed at constructing a novel cuproptosis model for analyzing the clinical features, mutation ...
Bin Liu +10 more
core +1 more source
MedComm – Oncology, 2023 Cuproptosis is a novel form of copper‐induced programmed cell death. Here, we investigate the role of cuproptosis‐related genes in head and neck squamous cell carcinoma (HNSCC), and the correlations between cuproptosis‐related genes and tumor ...
Zhangwei Hu, Wenbin Lei, Weiping Wen
doaj +1 more source
The value of cuproptosis-related differential genes in guiding prognosis and immune status in patients with skin cutaneous melanoma [PDF]
, 2023 Background: Skin cutaneous melanoma (SKCM) is one of the most common cutaneous malignancies, which incidence is increasing. Cuproptosis is a new type of programming cell death recently reported, which may affect the progression of SKCM.Method: The mRNA ...
Chufeng Jiang +4 more
core +1 more source
Role of cuproptosis in understanding diseases
Human Cell, 2023 Cell death is involved in a wide range of physiological and pathological processes. Recently, the term "cuproptosis" was coined to describe a novel type of cell death. This type of cell death, characterized by copper accumulation and proteotoxic stress, is a copper-dependent manner of death.
Shihan Cao +7 more
openaire +2 more sources
Frontiers in Immunology, 2023 Cuproptosis, a newly identified form of programmed cell death, plays vital roles in tumorigenesis. However, the interconnectivity of cuproptosis and ferroptosis is poorly understood.
Yefeng Shen +6 more
doaj +1 more source
Identification of a prognostic cuproptosis-related signature in hepatocellular carcinoma
Biology Direct, 2023 Background Cuproptosis is a new type of copper-induced cell death that is characterized by the aggregation of lipoylated tricarboxylic acid (TCA) cycle proteins. However, its role in hepatocellular carcinoma (HCC) remains unclear.
Yuqiao Chen +6 more
doaj +1 more source
Computational and Structural Biotechnology Journal, 2023 Background: Cuproptosis, a novel identified cell death form induced by copper, is characterized by aggregation of lipoylated mitochondrial enzymes and the destabilization of Fe–S cluster proteins.
Yanfei Shao +8 more
doaj +1 more source
Cuproptosis-related genes signature and validation of differential expression and the potential targeting drugs in temporal lobe epilepsy [PDF]
, 2023 Introduction: Temporal lobe epilepsy (TLE) is the most common subtype of epilepsy in adults and is characterized by neuronal loss, gliosis, and sprouting mossy fibers in the hippocampus.
Chunqing Zhang +16 more
core +1 more source
Editorial: Metabolic Regulation Under Oxidative Stress in Cancer [PDF]
, 2023 Oxidative stress has emerged as a key component of cancer metabolism that impacts multiple facets of tumor biology (1). Recent studies have shed light on the complex interplay of cellular redox and its impact on molecular mechanisms that govern metabolic
Bederman, Ilya +5 more
core +1 more source