Results 81 to 90 of about 4,249 (178)
ABSTRACT Keratitis–ichthyosis–deafness (KID) syndrome is a rare genetic condition typically presenting at birth with ichthyosiform erythroderma and bilateral hearing loss and later progressing to diffuse keratodermatous plaques with scaling. The condition is associated with mutations in the GJB2 gene, which lead to aberrant activation of connexin ...
Radhika Gupta +3 more
wiley +1 more source
Immunohistochemical Studies of Gap Junction in the Rat Liver with Anti-CX26 and Anti-CX32 Antibodies : Distributional Changes of CX32 and CX26 in the Rat Liver in the Developmental, Regenerating and Hepatocarcinogenic Stages [PDF]
Gap junctions are channels through which ions and small molecules are directly exchanged between adjacent cells, and consist of connexon. Connexon is composed of 6 connexin (CX) molecules, of which CX32 and CX26 have been isolated from the rat liver.
小山田, 正人 +2 more
core +1 more source
Association of STAT3 with Cx26 and Cx43 in human uterine endometrioid adenocarcinoma
Signal transducer and activator of transcription-3 (STAT3) drives endometrial carcinogenesis, while signaling via gap junctions gets weakened during cancer progression. Connexin 26 (Cx26), Cx43 and STAT3 were immunohistochemically evaluated in 78 endometrioid adenocarcinomas: Nuclear expression of STAT3 positively correlated with cytoplasmic ...
Urszula, Sulkowska +2 more
openaire +4 more sources
The Concise Guide to PHARMACOLOGY 2025/26: Ion channels
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +86 more
wiley +1 more source
Expression of connexins 26, 32 and 43 in the human colon--an immunohistochemical study.
Gap junctional intercellular communication (GJIC) is a mechanism for direct cell-to-cell signalling and is mediated by gap junctions (GJs), which consist of proteins called connexins (Cxs).
Maria Sobaniec-Lotowska +4 more
doaj +1 more source
ABSTRACT Keratosis–ichthyosis–deafness (KID) syndrome is a rare autosomal dominant ectodermal disease caused by mutations in the GJB2 gene, which encodes the gap junction protein Connexin 26 (Cx26) located on Chr. 13q12.11. This study presents the first mortality analysis associated with KID syndrome, focusing on a case report of a Latin American ...
Leslie Patrón‐Romero +17 more
wiley +1 more source
Gap junctions in healthy and diseases retina. Interneuronal gap junctions structured of connexin 36 and 45 present between retinal neurons provide passage for small molecules. Impaired conductivity of gap junctions participate in various retinal pathologies.
Anna Pacwa +3 more
wiley +1 more source
Insights into mechanisms of growth suppression by Cx26 in HeLa cells
Expression of gap junction proteins (connexins) has long been documented to suppress the neoplastic phenotype in various tumors and transformed cells. However, the molecular basis of this response is not well understood. To this end, we examined the effect on growth suppression of HeLa cells expressing 3 different connexins.
Anjana Chandrasekhar, Bruce J Nicholson
openaire +1 more source
The sharp frequency tuning and exquisite sensitivity of the mammalian cochlea is due to active forces delivered by outer hair cells (OHCs) to the cochlear partition.
Victoria A. Lukashkina +4 more
doaj +1 more source
Expression of Connexins 43, 26 and 32 in normal, hyperplastic and neoplastic perianal dog glands
Connexin (Cx) expression is reportedly altered in neoplasms. This study aimed to investigate the expression of Cx43, 26 and 32 in normal and pathological canine perianal glands.
Ana Maria C. R. P. F. Martins +5 more
doaj +1 more source

