Results 91 to 100 of about 1,002 (150)

Steroidogenic compensation and lipid deficiency with enhanced NAD+ salvage in small‐for‐gestational‐age placenta

The FEBS Journal, Volume 293, Issue 15, Page 4554-4577, August 2026.
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo, Lorenza Driul, Vanessa Tolotto, Eros Di Giorgio, Luigi E. Xodo   +4 more
wiley   +1 more source

Chk2 deletion rescues bone loss and cellular senescence induced by Bmi1 deficiency via regulation of Cyp1a1

Journal of Orthopaedic Translation
Background/objective: Bone homeostasis, maintained by a balance between osteoblastic bone formation and osteoclastic bone resorption, is disrupted in osteoporosis, leading to reduced bone mass and increased fracture risk.
Yining Liu, Xiaolei Ji, Jinge Zhang, Jinhong Lu, Boyang Liu, Haijian Sun, Dengshun Miao   +6 more
doaj   +1 more source

MiR‐18a‐5p Attenuates Oxidative Stress and Inhibits Lipid Accumulation in Alcoholic Fatty Liver by Activating the CYP1A1‐PPAR Axis

Immunity, Inflammation and Disease
Background Lipid deposition in alcoholic fatty liver disease (AFL) represents an early stage in alcoholic liver disease progression and may contribute to carcinogenesis.
XueMei Zhang, Wei Li, Ubaid Ullah, Ning Li, XinYu Geng, JiHan Qi, HongLiang Chen, Xu Zhang, Ying Hu, Lingling Yang, ShiZhu Jin   +10 more
doaj   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

The Association of CYP1A1 rs1048943 Polymorphism

The International Journal of Comprehensive Health, Medicine, & Dentistry
Breast cancer remains the most prevalent malignancy in women worldwide and its etiology involves genetic and environmental components. Among these genetic components, the CYP1A1 rs1048943 (Ile462Val) polymorphism has been shown to play a modifying role in breast cancer susceptibility based on its contribution to the metabolism of carcinogens and ...
openaire   +1 more source

Fulvic acid exhibits antitumor effects in ovarian cancer cells by upregulating cytochrome P450 family 1 subfamily A member 1 expression

Discover Oncology
Objective Fulvic acid (FA), a humic substance, has various applications in agricultural (animal husbandry) and pharmaceutical industries. However, to the best of our knowledge, its antitumor effects remain unclear.
Min Chen, Ming Cheng, Chenchen Shao, Wenwen Liang, Yi Tang, Fangjun Ding   +5 more
doaj   +1 more source

CYP1A1 Gene [PDF]

, 2020
openaire   +1 more source

Bioluminescence imaging of Cyp1a1-luciferase reporter mice demonstrates prolonged activation of the aryl hydrocarbon receptor in the lung

Communications Biology
Aryl hydrocarbon receptor (AHR) signalling integrates biological processes that sense and respond to environmental, dietary, and metabolic challenges to ensure tissue homeostasis.
Nicolas Veland, Hannah J. Gleneadie, Karen E. Brown, Alessandro Sardini, Joaquim Pombo, Andrew Dimond, Vanessa Burns, Karen Sarkisyan, Chris Schiering, Zoe Webster, Matthias Merkenschlager, Amanda G. Fisher   +11 more
doaj   +1 more source

Illuminating Role of CYP1A1 in Skin Function [PDF]

Journal of Investigative Dermatology, 2008
Rowe, Jo M., Welsh, Claire, Pena, Romi N., Wolf, C. Roland, Brown, Ken, Whitelaw, C. Bruce A.   +5 more
openaire   +3 more sources

Superinduction of CYP1A1 Gene Expression [PDF]

Journal of Biological Chemistry, 2000
Qiang Ma, Anthony J. Renzelli, Kimberly T. Baldwin, James M. Antonini   +3 more
openaire   +1 more source