Results 141 to 150 of about 34,953 (257)

Illuminating Role of CYP1A1 in Skin Function [PDF]

Journal of Investigative Dermatology, 2008
Rowe, Jo M., Welsh, Claire, Pena, Romi N., Wolf, C. Roland, Brown, Ken, Whitelaw, C. Bruce A.   +5 more
openaire   +3 more sources

CYP1A1 and CYP2E1 polymorphism frequencies in a large Brazilian population

, 2007
The enzymes encoded by the polymorphic genes CYP1A1 and CYP2E1 play an important role in the activation and inactivationofxenobiotics.Theseenzymeshavebeenassociatedwithxenobiotic-induceddiseases,suchascancer, therapeutic failure and adverse effects ...
Coura, Renata dos, Cabello, Pedro Hernan, Koifman, Rosalina J., Marques, Christiane de Fátima Silva, Koifman, Sergio, Hatagima, Ana   +5 more
core  

Bioluminescence imaging of Cyp1a1-luciferase reporter mice demonstrates prolonged activation of the aryl hydrocarbon receptor in the lung

Communications Biology
Aryl hydrocarbon receptor (AHR) signalling integrates biological processes that sense and respond to environmental, dietary, and metabolic challenges to ensure tissue homeostasis.
Nicolas Veland, Hannah J. Gleneadie, Karen E. Brown, Alessandro Sardini, Joaquim Pombo, Andrew Dimond, Vanessa Burns, Karen Sarkisyan, Chris Schiering, Zoe Webster, Matthias Merkenschlager, Amanda G. Fisher   +11 more
doaj   +1 more source

Genotype Frequencies of Polymorphic GSTM1, GSTT1, and Cytochrome P450 CYP1A1 in Mexicans

, 2007
The genotype frequencies of three metabolic polymorphisms were determined in a sample of a typical community in central Mexico. CYP1A1*3, GSTM1, and GSTT1 polymorphisms were studied in 150 donors born in Mexico and with Mexican ascendants; with respect ...
Mejia-Loza, Vanessa, Carranza, Paloma, Araujo, Antonio, Montero, Regina   +3 more
core   +1 more source

Superinduction of CYP1A1 Gene Expression [PDF]

Journal of Biological Chemistry, 2000
Qiang Ma, Anthony J. Renzelli, Kimberly T. Baldwin, James M. Antonini   +3 more
openaire   +1 more source

Study of the correlation between CYP1A1 gene promoter methylation and smoking in gastric cancer patients

Fiyz̤, 2019
Background: Gastric cancer is one of the main causes of cancer related deaths particularly in northern parts of Iran. It has been recently attributed to the increased application of agricultural pesticides in these areas.
Leili Sadeghi-Amiri , Ali Barzegar , Novin Nikbakhsh-Zati, Pooyan Mehraban   +3 more
doaj  

Perfluorooctane sulfonate (PFOS) interferes with Cyp1a activity and dysregulates the aryl hydrocarbon receptor pathway in larval zebrafish (Danio rerio). [PDF]

Environ Pollut
Miller DH, Lachapelle A, Satbhai KM, Chien P, Borys KA, Timme-Laragy AR.   +5 more
europepmc   +1 more source

CYP1A1 wt Allele [PDF]

, 2020
openaire   +1 more source

CYP1A1 as a conserved metabolic circuit linking environmental sensing to immune regulation

Cytochrome P450 1A1 (CYP1A1) is traditionally described as a xenobiotic detoxification enzyme induced by the aryl hydrocarbon receptor (AhR). However, its tight inducible regulation, evolutionary conservation, and prominent expression in immune and ...
Sailis, Ardie Barry
core   +1 more source

Identification of Potent and Selective CYP1A1 Inhibitors via Combined Ligand and Structure-Based Virtual Screening and Their in Vitro Validation in Sacchrosomes and Live Human Cells

Journal of Chemical Information and Modeling, 2017
P. Joshi, Glen J. P. McCann, V. Sonawane, R. Vishwakarma, B. Chaudhuri, S. Bharate   +5 more
semanticscholar   +1 more source