Results 21 to 30 of about 15,644 (193)
Clinical and Experimental Hypertension, 2017 Aims: To investigate the association of CYP1A1 genotype and additional gene–smoking interaction with coronary artery disease (CAD) risk based on a Chinese case-control study.
Dao-Di Peng, Wei Xie, Zai-Xin Yu
doaj +1 more source
PLoS ONE, 2021 BackgroundNine previous meta-analyses have been published to analyze the CYP1A1 T3801C and A2455G polymorphisms with BC risk. However, they did not assess the credibility of statistically significant associations.
Chen Yang, Xiao-Feng He
doaj +1 more source
Signal integration by the CYP1A1 promoter -- a quantitative study [PDF]
Nucleic Acids Research, 2015 Genes involved in detoxification of foreign compounds exhibit complex spatiotemporal expression patterns in liver. Cytochrome P450 1A1 (CYP1A1), for example, is restricted to the pericentral region of liver lobules in response to the interplay between aryl hydrocarbon receptor (AhR) and Wnt/β-catenin signaling pathways. However, the mechanisms by which
Schulthess, P. +6 more
openaire +4 more sources
Interaction between maternal passive smoking during pregnancy and CYP1A1 and GSTs polymorphisms on spontaneous preterm delivery. [PDF]
PLoS ONE, 2012 OBJECTIVE: The present study aimed to examine the association between maternal passive smoking during pregnancy and the risk of spontaneous PTD and to explore the potential interaction of the single or joint gene polymorphism of CYP1A1 and GSTs with ...
Yi-Juan Luo +12 more
doaj +1 more source
Expression and Sequence of CYP1A1 in the Camel
Journal of Veterinary Medical Science, 2010 In this study, we determined a partial sequence of CYP1A1 in the camel and its phylogenetic position. The deduced amino acid sequence of camel CYP1A1 showed the highest identity 94% with those of sheep and cattle CYP1A1. In a phylogenetic analysis, the camel CYP1A1 isoform was located beside sheep and cattle CYP1A1.
DARWISH, Wageh Sobhy +5 more
openaire +3 more sources
Sp1, Instead of AhR, Regulates the Basal Transcription of Porcine CYP1A1 at the Proximal Promoter
Frontiers in Pharmacology, 2018 Pigs are commonly used as an animal model to evaluate the toxic effects of exogenous compounds. Cytochrome P450 1A1 (CYP1A1) metabolizes numerous exogenous compounds and is abundantly expressed in the liver, kidneys, and intestines.
Xuan Xie +11 more
doaj +1 more source
Frontiers in Microbiology, 2022 BackgroundHost-microbiota crosstalk has been implicated in multiple host metabolic pathway axes that regulate intestinal barrier function. Although constitutive cytochrome P4501A1 (CYP1A1) expression perturbs the microbiome-derived autoregulatory loop ...
Xiaoyuan Ma +13 more
doaj +1 more source
Modulation of CYP1A1 and CYP1A2 hepatic enzymes after oral administration of Chios mastic gum to male Wistar rats. [PDF]
PLoS ONE, 2014 Chios mastic gum (CMG), a resin derived from Pistacia lentiscus var. chia, is known since ancient times for its pharmacological activities. CYP1A1 and CYP1A2 enzymes are among the most involved in the biotransformation of chemicals and the metabolic ...
Efrosini S Katsanou +5 more
doaj +1 more source
Frequency of CYP1A1*2A polymorphisms and deletion of the GSMT1 gene in a Peruvian mestizo population [PDF]
Pharmacia, 2021 The polymorphic variants of CYP1A1 and the deletion of GSTM1 are present in the Peruvian mestizo population. Wild type and mutated genotypes (WT/*2A and *2A/ *2A) were identified, whose allele frequencies are 0.31 (T allele) and 0.69 (C allele ...
Angel Tito Alvarado +9 more
doaj +3 more sources
Expression profiles of CYP1A1 and CYP1B1 enzymes in Non-small Cell Lung Cancer of Turkish Patients
Сибирский онкологический журналBackground. The cytochrome P450 enzymes CYP1A1 and CYP1B1 are involved in the metabolism of carcinogens and have been linked to various cancers, including lung cancer, primarily through their overexpression in tumor tissues. Aim of study.
H. Bayram +7 more
doaj +1 more source