Results 11 to 20 of about 763,623 (189)

Mitochondria-Derived Damage-Associated Molecular Patterns in Neurodegeneration [PDF]

Frontiers in Immunology, 2017
Inflammation is increasingly implicated in neurodegenerative disease pathology. As no acquired pathogen appears to drive this inflammation, the question of what does remains.
Russell H. Swerdlow, Russell H. Swerdlow, Russell H. Swerdlow, Russell H. Swerdlow, Heather M. Wilkins, Heather M. Wilkins, Ian W. Weidling, Ian W. Weidling, Yan Ji, Yan Ji   +9 more
doaj   +3 more sources

Changes of Damage Associated Molecular Patterns in COVID-19 Patients

Infectious Diseases & Immunity, 2021
. Background:. The development of severe coronavirus disease 2019 (COVID-19) is associated with systemic hyperinflammation, which drives multi-organ failure and death.
Xing Fan, Jin-Wen Song, Si-Yu Wang, Wen-Jing Cao, Xiu-Wen Wang, Ming-Ju Zhou, Tao Yang, Chun-Bao Zhou, Jun Hou, Ji-Yuan Zhang, Fan-Ping Meng, Ming Shi, Fu-Sheng Wang, Chao Zhang, Haijuan Wang   +14 more
doaj   +4 more sources

Kinetics of Circulating Damage-Associated Molecular Patterns in Sepsis [PDF]

Journal of Immunology Research, 2015
Circulating levels of conventional biomarkers and damage-associated molecular patterns were examined in 30 severe sepsis patients (20 survivors and 10 nonsurvivors).
Takahiro Miki, Toshiaki Iba
doaj   +3 more sources

Damage-associated molecular patterns and coagulation. [PDF]

Br J Haematol
Damage‐associated molecular patterns (DAMPs), released into the extracellular space following tissue injury, are increasingly recognised as potent procoagulant molecules integral to haemostasis and the pathogenesis of thrombosis. Their procoagulant influence spans all phases of the cell‐based model of coagulation while simultaneously extending beyond ...
Yong J, Toh CH.
europepmc   +2 more sources

The Role of Mitochondrial Damage-Associated Molecular Patterns in Chronic Neuroinflammation

Mediators of Inflammation, 2019
Mitochondrial dysfunction has been established as a common feature of neurodegenerative disorders that contributes to disease pathology by causing impaired cellular energy production.
Ekta Bajwa, Caitlin B. Pointer, Andis Klegeris   +2 more
doaj   +3 more sources

Damage-associated molecular patterns (DAMPs) in vascular diseases. [PDF]

J Biol Chem
Research into the role of chronic sterile inflammation (i.e. a prolonged inflammatory state not caused by an infectious agent), in vascular disease progression has continued to grow over the last few decades. DAMPs have a critical role in this research due to their ability to link stress-causing cardiovascular risk factors to inflammatory phenotypes ...
Antonello J, Roy P.
europepmc   +3 more sources

Damage-Associated Molecular Patterns (DAMPs) in Retinal Disorders. [PDF]

Int J Mol Sci, 2022
Damage-associated molecular patterns (DAMPs) are endogenous danger molecules released from the extracellular and intracellular space of damaged tissue or dead cells. Recent evidence indicates that DAMPs are associated with the sterile inflammation caused by aging, increased ocular pressure, high glucose, oxidative stress, ischemia, mechanical trauma ...
Mahaling B, Low SWY, Beck M, Kumar D, Ahmed S, Connor TB, Ahmad B, Chaurasia SS.   +7 more
europepmc   +4 more sources

Activated Carbon for Sepsis Prevention and Intervention: A Modern Way of Utilizing Old Therapies

C, 2023
(1) Background: Uncontrolled inflammation often contributes to life-threatening sepsis sequela such as multi-organ dysfunction syndrome (MODS), and is accompanied by abnormal levels of pathological and damage-associated molecular patterns (PAMPs & DAMPs)
Elisaveta Snezhkova, Heinz Redl, Johannes Grillari, Marcin Osuchowski   +3 more
doaj   +1 more source

Damage associated molecular pattern molecules [PDF]

Clinical Immunology, 2007
Members of the Federation of Clinical Immunology Societies are invited to attend an exciting meeting on damage associated molecular pattern molecules [DAMPs] in acute and chronic inflammation including cancer. This day long interactive symposium is going to be held in San Diego June 7th, 2007 as part of the Annual FOCiS meeting. The Clinical Immunology
Michael T, Lotze, Albert, Deisseroth, Anna, Rubartelli   +2 more
openaire   +2 more sources

Damage-associated molecular patterns in trauma [PDF]

European Journal of Trauma and Emergency Surgery, 2019
AbstractIn 1994, the “danger model” argued that adaptive immune responses are driven rather by molecules released upon tissue damage than by the recognition of “strange” molecules. Thus, an alternative to the “self versus non-self recognition model” has been provided.
Relja, Borna, Land, Walter Gottlieb
openaire   +2 more sources