Results 31 to 40 of about 89,563 (272)

Trial watch: Dendritic cell-based anticancer immunotherapy

OncoImmunology, 2017
Dendritic cell (DC)-based vaccines against cancer have been extensively developed over the past two decades. Typically DC-based cancer immunotherapy entails loading patient-derived DCs with an appropriate source of tumor-associated antigens (TAAs) and ...
Abhishek D. Garg, Monica Vara Perez, Marco Schaaf, Patrizia Agostinis, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi   +6 more
doaj   +1 more source

Docosahexaenoic acid (DHA) promotes immunogenic apoptosis in human multiple myeloma cells, induces autophagy and inhibits STAT3 in both tumor and dendritic cells [PDF]

, 2017
Docosahexaenoic acid (DHA), a ω-3 polyunsaturated fatty acid found in fish oil, is a multi-target agent and exerts anti-inflammatory and anticancer activities alone or in combination with chemotherapies.
D'Eliseo, Donatella, DI RENZO, Livia Maria, Santoni, Angela, Velotti, Francesca   +3 more
core   +1 more source

GRP-3 and KAPP, encoding interactors of WAK1, negatively affect defense responses induced by oligogalacturonides and local response to wounding [PDF]

, 2016
Conserved microbe-associated molecular patterns (MAMPs) and damage-associated molecular patterns (DAMPs) act as danger signals to activate the plant immune response.
CERVONE, Felice, DE LORENZO, Giulia, GRAMEGNA, GIOVANNA, MODESTI, VANESSA, SAVATIN, DANIEL VALENTIN, SICILIA, Francesca   +5 more
core   +1 more source

Damage-associated molecular patterns (DAMPs) related to immunogenic cell death are differentially triggered by clinically relevant chemotherapeutics in lung adenocarcinoma cells

BMC Cancer, 2020
Background Chemotherapeutics can stimulate immune antitumor response by inducing immunogenic cell death (ICD), which is activated by Damage-Associated Molecular Patterns (DAMPs) like the exposure of calreticulin (CRT) on the cell surface, the release of ...
José Ignácio Gonzalez Solari, Eduardo Filippi-Chiela, Emily Salles Pilar, Vitória Nunes, Esteban Alberto Gonzalez, Fabrício Figueiró, Cristiano Feijó Andrade, Fábio Klamt   +7 more
doaj   +1 more source

Porphyromonas gingivalis lipopolysaccharide induced RIPK3/MLKL-mediated necroptosis of oral epithelial cells and the further regulation in macrophage activation

Journal of Oral Microbiology, 2022
Necroptosis, a new type of regulated cell death with massive release of damage-associated molecular patterns (DAMPs), is involved in the pathogenesis of periodontitis.
Fengxue Geng, Junchao Liu, Chengcheng Yin, Shuwei Zhang, Yaping Pan, Hongchen Sun   +5 more
doaj   +1 more source

Recognition of damage-associated, nucleic acid-related molecular patterns during inflammation and vaccination

Frontiers in Cellular and Infection Microbiology, 2013
All mammalian cells are equipped with large numbers of sensors for protection from various sorts of invaders, who, in turn, are equipped with molecules containing pathogen-associated molecular patterns (PAMPs).
Nao eJounai, Nao eJounai, Kouji eKobiyama, Kouji eKobiyama, Fumihiko eTakeshita, Fumihiko eTakeshita, Ken J. Ishii, Ken J. Ishii   +7 more
doaj   +1 more source

Tissue Microenvironments Define and Get Reinforced by Macrophage Phenotypes in Homeostasis or during Inflammation, Repair and Fibrosis [PDF]

, 2012
Current macrophage phenotype classifications are based on distinct in vitro culture conditions that do not adequately mirror complex tissue environments.
Weidenbusch, Marc, Anders, Hans-Joachim
core   +1 more source

Quasinormal modes of gravitational perturbation around a Schwarzschild black hole surrounded by quintessence

, 2006
In this paper, the quasinormal modes of gravitational perturbation around a Schwarzschild black hole surrounded by quintessence were evaluated by using the third-order WKB approximation.
Bacon D J, Capozziello S, Cardoso V, Chandrasekhar S, Chandrasekhar S, Chen S B, Chen S B, Chen S B, Crisóstomo J, Daghigh R G, Einsenhart L P, Giammatteo M, Kaiser N, Kiselev V V, Kokkotas K D, Kokkotas K D, Leaver E W, Maldacena J M, Medved A J M, Nollert H P, Ruiz-Lapuente P, Scranton R, Wei H, Witten E, Y X Gui, Yu Zhang, Zhang H B   +26 more
core   +1 more source

DNA Checkpoint and Repair Factors Are Nuclear Sensors for Intracellular Organelle Stresses-Inflammations and Cancers Can Have High Genomic Risks. [PDF]

, 2018
Under inflammatory conditions, inflammatory cells release reactive oxygen species (ROS) and reactive nitrogen species (RNS) which cause DNA damage. If not appropriately repaired, DNA damage leads to gene mutations and genomic instability.
Chen, Hongping, Choi, Eric T., Cueto, Ramon, Drosatos, Konstantinos, Fu, Hangfei, Nanayakkara, Gayani K, Park, Joon Y., Qin, Xuebin, Shao, Lijian, Shao, Ying, Sheng, Haitao, Sun, Jianxin, Sun, Yu, Wang, Hong, Wang, Luqiao, Wu, Na, Yang, Qian, Yang, William Y, Yang, Wuping, Yang, Xiaofeng, Zeng, Huihong, Zhu, Qingxian   +21 more
core   +2 more sources

Extracellular Vesicles and DAMPs in Cancer: A Mini-Review

Frontiers in Immunology, 2021
Certain cancer therapy has been shown to induce immunogenic cell death in cancer cells and may promote tumor progression instead. The external stress or stimuli may induce cell death and contribute toward the secretion of pro inflammatory molecules.
Nadiah Abu, Nurul Ainaa Adilah Rus Bakarurraini, Siti Nurmi Nasir   +2 more
doaj   +1 more source