Results 101 to 110 of about 3,926 (154)

The CCR4-NOT complex: a multifaceted sensor of molecular signals instructing eukaryotic mRNA translation and stability. [PDF]

Nucleic Acids Res
Caulier G, Siblini J, Sène L, Mauxion F, Séraphin B.   +4 more
europepmc   +1 more source

Insights into the recruitment of the PAN2-PAN3 deadenylase complex to miRNA targets by the GW182/TNRC6 proteins

, 2013
The PAN2-PAN3 deadenylase complex functions in general and miRNA-mediated mRNA degradation and is specifically recruited to miRNA targets by the TNRC6 proteins. PAN3 is an adaptor protein that recruits the PAN2 deadenylase to mRNA targets.
Huntzinger, E., Weichenrieder, O. ; https://orcid.org/, Boland, A., Christie, M., Izaurralde, E. ; https://orcid.org/   +4 more
core  

Human pumilio proteins use fuzzy multivalent hydrophobic interactions to recruit the CCR4-NOT deadenylase complex to repress mRNAs. [PDF]

J Biol Chem
Dunshee EB, Saladin BA, Turner DJ, Qiu C, Dutcher RC, Williams JG, Corbo J, Wolcott OR, Korte AJ, Haugen RJ, Tanaka Hall TM, Valkov E, Goldstrohm AC.   +12 more
europepmc   +1 more source

The CCR4-NOT deadenylase complex mediates tubulin autoregulation <i>via</i> specific adapters CNOT10 and CNOT11. [PDF]

MicroPubl Biol
Sarbanes SL, Hogg JR, Roll-Mecak A.
europepmc   +1 more source

Cytoplasmic poly-adenosine binding proteins modulate susceptibility of mRNAs to Pumilio-mediated decay. [PDF]

Nucleic Acids Res
McKenney KM, Hernandez-Perez C, Dunshee EB, Pum JM, DesMarais AJ, Connacher RP, Goldstrohm AC.   +6 more
europepmc   +1 more source

Deadenylation and decapping factors cooperatively stimulate biochemical activities of DEAD-box ATPase Dhh1. [PDF]

Nucleic Acids Res
Braun GA, Kumar R, Hinnebusch AG, Gross JD.   +3 more
europepmc   +1 more source

RNA triple helix assembled by the poly(A) tail enhances retrotransposon mobilization by preventing RNA deadenylation. [PDF]

Proc Natl Acad Sci U S A
Li H, Wang L, Lei Z, Biacsi AS, Jeong DH, Cho J.   +5 more
europepmc   +1 more source

Human CCR4 deadenylase homolog Angel1 is a non-stop mRNA decay factor. [PDF]

RNA
Nicholson-Shaw T, Dowdle ME, Ajaj Y, Perelis M, Fulzele A, Yeo GW, Bennett EJ, Lykke-Andersen J.   +7 more
europepmc   +1 more source

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity. [PDF]

FEBS Open Bio
Soeda S, Montrose M, Takahashi A, Ishida R, Burriel S, Ohmine N, Natsume T, Adachi S, Kim M, Yamamoto T.   +9 more
europepmc   +1 more source

Viral Strategies and Cellular Countermeasures That Regulate mRNA Access to the Translation Apparatus: Second Edition. [PDF]

Viruses
Hellen CUT.
europepmc   +1 more source