Results 21 to 30 of about 32,113 (291)
Intranasal deferoxamine can improve memory in healthy C57 mice, suggesting a partially non‐disease‐specific pathway of functional neurologic improvement [PDF]
Brain and Behavior, 2020 Intranasal deferoxamine (IN DFO) has been shown to decrease memory loss and have beneficial impacts across several models of neurologic disease and injury, including rodent models of Alzheimer's and Parkinson's disease.
Jared M. Fine +8 more
openalex +2 more sources
Journal of Translational Medicine, 2022 Background Radiation-induced skin injury is a well-known risk factor for impaired wound healing. Over time, the deleterious effects of radiation on skin produce a fibrotic, hypovascular dermis poorly suited to wound healing.
Hendrik Lintel +10 more
semanticscholar +1 more source
Frontiers in Physiology, 2022 Ferritinophagy is one of the most recent molecular mechanisms affecting cardiac function. In addition, it is one of the pathways by which doxorubicin, one of the anticancer drugs commonly used, negatively impacts the cardiac muscle, leading to cardiac ...
Mira Hanna +10 more
semanticscholar +1 more source
Prevalence of symptoms in patients poisoned with iron in Ahvaz Razi Hospital in 2014-2017 [PDF]
Asia Pacific Journal of Medical Toxicology, 2020 Background: Iron is an important element for normal cell metabolism, but in excess amounts is quite cytotoxic, and even deadly. Iron poisoning is a calamity repeated many times in the world.
Ali hassan Rahmani +2 more
doaj +1 more source
Mechanisms of Intranasal Deferoxamine in Neurodegenerative and Neurovascular Disease
Pharmaceuticals, 2021 Identifying disease-modifying therapies for neurological diseases remains one of the greatest gaps in modern medicine. Herein, we present the rationale for intranasal (IN) delivery of deferoxamine (DFO), a high-affinity iron chelator, as a treatment for ...
Jacob Kosyakovsky +3 more
semanticscholar +1 more source
Molecular Pharmaceutics, 2020 Deferoxamine mesylate (DFO) is an FDA-approved, hexadentate iron chelator routinely used to alleviate systemic iron burden in thalassemia major and sickle cell patients.
A. C. Farr, May P. Xiong
semanticscholar +1 more source
DEVELOPMENT OF AN ANALYTICAL METHOD FOR THE DETERMINATION OF LEAD BASED ON LOCAL SURFACE PLASMON RESONANCE OF SILVER NANOPARTICLES [PDF]
Química Nova, 2020 Lead is environmental pollutant that even in low trace is harmful for human health and wildlife. In this study we presented a colorimetric method for determination of Pb2+ in water by aggregation of silver nanoparticles capped citrate in the presence of ...
Hamed Azimi +4 more
doaj +1 more source
Neuropilin-1 Controls Endothelial Homeostasis by Regulating Mitochondrial Function and Iron-Dependent Oxidative Stress. [PDF]
, 2018 The transmembrane protein neuropilin-1 (NRP1) promotes vascular endothelial growth factor (VEGF) and extracellular matrix signaling in endothelial cells (ECs).
Bosseboeuf, E +8 more
core +3 more sources
Neuroprotective effect of deferoxamine on erastin-induced ferroptosis in primary cortical neurons
Neural Regeneration Research, 2020 The iron chelator deferoxamine has been shown to inhibit ferroptosis in spinal cord injury. However, it is unclear whether deferoxamine directly protects neurons from ferroptotic cell death.
Yan Zhang +11 more
semanticscholar +1 more source
BMC Ophthalmology, 2021 Background Deferoxamine retinopathy is the informally designated term used to describe a characteristic pattern of outer retinal degeneration in iron-overloaded chronic anemia patients who are treated with deferoxamine. We hypothesize that insufficiently
Mohamed Belmouhand +5 more
doaj +1 more source