Results 1 to 10 of about 17,143 (248)

Metabolic Regulation Effect and Potential Metabolic Biomarkers of Pre-Treated Delphinidin on Oxidative Damage Induced by Paraquat in A549 Cells [PDF]

Foods, 2022
Delphinidin (Del) is an anthocyanin component with high in vitro antioxidant capacity. In this study, based on the screening of a cell model, gas chromatography-time of flight mass spectrometry (GC-TOF/MS) was used to evaluate the effect of Del pre ...
Yongli Ye, Jian Ji, Yaoguang Huang, Yinzhi Zhang, Xiulan Sun   +4 more
doaj   +2 more sources

Chemistry and Pharmacological Actions of Delphinidin, a Dietary Purple Pigment in Anthocyanidin and Anthocyanin Forms [PDF]

Frontiers in Nutrition, 2022
Anthocyanins are naturally occurring water-soluble flavonoids abundantly present in fruits and vegetables. They are polymethoxyderivatives of 2-phenyl-benzopyrylium or flavylium salts. Delphinidin (Dp) is a purple-colored plant pigment, which occurs in a
Asif Husain, Harshit Chanana, Shah Alam Khan, U. M. Dhanalekshmi, M. Ali, Anwar A. Alghamdi, Aftab Ahmad   +6 more
doaj   +2 more sources

Cytoprotective Effects of Delphinidin for Human Chondrocytes against Oxidative Stress through Activation of Autophagy [PDF]

Antioxidants, 2020
Antioxidant enzymes are decreased in osteoarthritis (OA) patients, implying the role of oxidative stress in osteoarthritis pathogenesis. The aim of this study was to evaluate the cytoprotective effects of delphinidin, a potent antioxidant, in human ...
Dong-Yeong Lee, Young-Jin Park, Myung-Geun Song, Deok Ryong Kim, Sahib Zada, Dong-Hee Kim   +5 more
doaj   +2 more sources

Delphinidin Inhibits LPS-Induced MUC8 and MUC5B Expression Through Toll-like Receptor 4-Mediated ERK1/2 and p38 MAPK in Human Airway Epithelial Cells [PDF]

Clinical and Experimental Otorhinolaryngology, 2014
ObjectivesDelphinidin is one of the anthocyanidins. It is believed to have anti-inflammatory property including antioxidant, antiangiogenic, and anti-cancer properties.
Chang Hoon Bae, Bo Sung Jeon, Yoon Seok Choi, Si-Youn Song, Yong-Dae Kim   +4 more
doaj   +3 more sources

Delphinidin attenuates cognitive deficits and pathology of Alzheimer’s disease by preventing microglial senescence via AMPK/SIRT1 pathway [PDF]

Alzheimer’s Research & Therapy
Background Emerging evidence suggests that senescent microglia play a role in β-amyloid (Aβ) pathology and neuroinflammation in Alzheimer’s disease (AD).
Ying Liu, Ting Hong, Mingxuan Lv, Xiaoyu Guo, Panpan Zhang, Aijuan Yan, Wenshi Wei   +6 more
doaj   +2 more sources

A Delphinidin-Enriched Maqui Berry Extract Improves Bone Metabolism and Protects against Bone Loss in Osteopenic Mouse Models [PDF]

Antioxidants, 2019
In our previous investigation, delphinidin, one of the most abundant anthocyanins found in vegetables and berry fruits, had been shown to inhibit osteoclasts and prevent bone loss in mouse models of osteoporosis.
Masahiro Nagaoka, Toyonobu Maeda, Masahiro Chatani, Kazuaki Handa, Tomoyuki Yamakawa, Shuichi Kiyohara, Takako Negishi-Koga, Yasumasa Kato, Masamichi Takami, Shumpei Niida, Stefanie C. Lang, Marlena C. Kruger, Keiko Suzuki   +12 more
doaj   +2 more sources

In-Depth Exploration of the Coloration Mechanism of Iris dichotoma Pall. via Transcriptomic and Metabolomic Analyses [PDF]

Plants
Iris dichotoma Pall., renowned for its high ornamental value, is frequently cultivated in flowerbeds and courtyards, endowing garden landscapes with unique allure. Dark-hued flowers are widely regarded as more aesthetically appealing. This study utilized
Yalin Yu, Xiaojing Qiang, Fan Huang, Xiuzheng Huang, Lei Liu   +4 more
doaj   +2 more sources

Inhibition of triple-negative breast cancer growth via delphinidin-mediated suppression of the JAK2/STAT3/PD-L1 pathway

Food & Nutrition Research
Background: Breast cancer is a leading cause of cancer-related mortality among women globally, with triple-negative breast cancer (TNBC) being particularly aggressive.
Xiaoping Yu, Xiaolong Song, Jiali Yan, Ziting Xiong, Lujie Zheng, Yan Luo, Fengcheng Deng, Yanfeng Zhu   +7 more
doaj   +3 more sources

Delphinidin upregulates microRNA-let-7b expression through family with sequence similarity 222 member B [PDF]

Scientific Reports
Delphinidin is a major anthocyanidin belonging to the flavonoid family with pharmacological activities against cancer, inflammation, and muscle atrophy. However, the mechanism regulating its activity is yet to be completely elucidated.
Motoki Murata, Yuki Marugame, Shuhei Yamada, I-Chian Lin, Shuya Yamashita, Motofumi Kumazoe, Yoshinori Fujimura, Hirofumi Tachibana   +7 more
doaj   +2 more sources

Exploring anti-SARS-CoV-2 natural products: dual-viral target inhibition by delphinidin and the anti-coronaviral efficacy of deapio platycodin D. [PDF]

Nat Prod Bioprospect
Lu J, Tang Y, Li H, Tian S, Chen X, Song X, Qin P, Xu J, Zhu H, Ni L, Du H, Zhang W, Li W, Chen L.   +13 more
europepmc   +3 more sources