Results 11 to 20 of about 11,862 (217)

Cytoprotective Effects of Delphinidin for Human Chondrocytes against Oxidative Stress through Activation of Autophagy

open access: yesAntioxidants, 2020
Antioxidant enzymes are decreased in osteoarthritis (OA) patients, implying the role of oxidative stress in osteoarthritis pathogenesis. The aim of this study was to evaluate the cytoprotective effects of delphinidin, a potent antioxidant, in human ...
Dong-Yeong Lee   +5 more
doaj   +2 more sources

Delphinidin induced protective autophagy via mTOR pathway suppression and AMPK pathway activation in HER-2 positive breast cancer cells

open access: yesBMC Cancer, 2018
Background We have previously demonstrated the anticancer effect of anthocyanins. In this study, we explored the biological activities of delphinidin, the most common of the anthocyanidin monomers, that were related to autophagy in HER-2 positive breast ...
Jingyao Chen   +9 more
doaj   +2 more sources

Analysis of Delphinidin and Luteolin Genotoxicity in Human Lymphocyte Culture [PDF]

open access: yesJournal of Health Sciences, 2015
Introduction: Bioflavonoids delphinidin (2-(3,4,5-Trihydroxyphenyl)chromenylium-3,5,7-triol) and luteolin (2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-chromenone) have been recognized as promising antioxidants and anticancer substances. Due to their extensive use, the goal of the research was to determine whether they have any genotoxic potential in vitro ...
Jasmin Ezić   +5 more
openaire   +3 more sources

Delphinidin prevents high glucose-induced cell proliferation and collagen synthesis by inhibition of NOX-1 and mitochondrial superoxide in mesangial cells [PDF]

open access: yesJournal of Pharmacological Sciences, 2016
This study examined the effect of delphinidin on high glucose-induced cell proliferation and collagen synthesis in mesangial cells. Glucose dose-dependently (5.6–25 mM) increased cell proliferation and collagen I and IV mRNA levels, whereas pretreatment ...
Seung Eun Song   +5 more
doaj   +2 more sources

Delphinidin, one of the major anthocyanidins, prevents bone loss through the inhibition of excessive osteoclastogenesis in osteoporosis model mice. [PDF]

open access: yesPLoS ONE, 2014
Anthocyanins, one of the flavonoid subtypes, are a large family of water-soluble phytopigments and have a wide range of health-promoting benefits. Recently, an anthocyanin-rich compound from blueberries was reported to possess protective property against
Sawako Moriwaki   +7 more
doaj   +2 more sources

Administration of Delphinidin to Improve Survival and Neurological Outcome in Mice After Cardiac Arrest and Resuscitation

open access: yesAntioxidants
Reactive oxygen species (ROS) play an important role in ischemia–reperfusion (I/R) after cardiac arrest and cardiopulmonary resuscitation (CA-CPR). Early administration of vitamin C at a high dose in experimental models resulted in less myocardial damage
Rika Bajorat   +6 more
doaj   +2 more sources

Evaluation of delphinidin as a storage medium for avulsed teeth

open access: yesBMC Oral Health, 2023
Abstract Background Delphinidin (DP), an anthocyanidin found in blueberries, has antioxidant and anti-inflammatory effects. This study aimed to investigate the efficacy of DP as a storage medium for avulsed teeth. Methods Human periodontal ligament cells were cultured and ...
Ok Hyung Nam   +7 more
openaire   +3 more sources

The conversion of procyanidins and prodelphinidins to cyanidin and delphinidin [PDF]

open access: yesPhytochemistry, 1985
The hydrolysis of proanthocyanidins to anthocyanidins in n-BuOH-HCl (95:5) has been shown to be an autoxidation, the yield of anthocyanidin being critically dependent on trace metal-ion impurities. Reproducible yields of anthocyanidin may be achieved if iron (III) salts are added to the reaction medium, and a standard method of analysis of ...
Porter, Lawrence J.   +2 more
openaire   +1 more source

Identification of Anthocyanin Compounds in Butterfly Pea Flowers (Clitoria ternatea L.) by Ultra Performance Liquid Chromatography/Ultraviolet Coupled to Mass Spectrometry

open access: yesMolecules, 2021
Butterfly pea flower have great sensory attraction, but they have not yet been used widely in Vietnam. Extracts of butterfly pea flowers can be used conveniently as a natural blue colorant for food products.
Nguyen Minh Thuy   +5 more
doaj   +1 more source

Delphinidin inhibits VEGF induced-mitochondrial biogenesis and Akt activation in endothelial cells. [PDF]

open access: yes, 2014
Delphinidin, an anthocyanin present in red wine, has been reported to exert vasculoprotective properties on endothelial cells, including vasorelaxing and anti-apoptotic effects.
G. Simard   +4 more
core   +2 more sources

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