Results 11 to 20 of about 11,663 (212)
Cytotoxic effects of delphinidin in human osteosarcoma cells
Acta Orthopaedica et Traumatologica Turcica, 2018 Introduction: The aim of this study was to evaluate whether delphinidin is cytoprotective or cytotoxic in osteosarcoma cell lines, and to elucidate the underlying mechanisms.
Dong-Yeong Lee +5 more
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Antioxidants, 2020 Antioxidant enzymes are decreased in osteoarthritis (OA) patients, implying the role of oxidative stress in osteoarthritis pathogenesis. The aim of this study was to evaluate the cytoprotective effects of delphinidin, a potent antioxidant, in human ...
Dong-Hee Kim +2 more
exaly +4 more sources
Targeting cancer with delphinidin: from molecular insights to therapeutic implications [PDF]
Frontiers in PharmacologyDelphinidin is a natural anthocyanidin abundant in various fruits, vegetables, and flowers. It has garnered significant attention due to its potent antioxidant activity and extensive anticancer potential.
Yuhong Xu +5 more
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Breast Cancer: Basic and Clinical Research, 2011 Delphinidin is a polyphenolic compound found in many brightly colored fruits and vegetables. Delphinidin is also the major bioactive component found in many dietary supplements that are currently consumed as complementary cancer medicine including ...
Tuba Ozbay, Rita Nahta
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Delphinidin Inhibits Tumor Growth by Acting on VEGF Signalling in Endothelial Cells. [PDF]
PLoS ONE, 2015 The vasculoprotective properties of delphinidin are driven mainly by its action on endothelial cells. Moreover, delphinidin displays anti-angiogenic properties in both in vitro and in vivo angiogenesis models and thereby might prevent the development of ...
Thérèse Keravis +9 more
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BMC Cancer, 2018 Background We have previously demonstrated the anticancer effect of anthocyanins. In this study, we explored the biological activities of delphinidin, the most common of the anthocyanidin monomers, that were related to autophagy in HER-2 positive breast ...
Jingyao Chen +9 more
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Analysis of Delphinidin and Luteolin Genotoxicity in Human Lymphocyte Culture [PDF]
Journal of Health Sciences, 2015 Introduction: Bioflavonoids delphinidin (2-(3,4,5-Trihydroxyphenyl)chromenylium-3,5,7-triol) and luteolin (2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-chromenone) have been recognized as promising antioxidants and anticancer substances. Due to their extensive use, the goal of the research was to determine whether they have any genotoxic potential in vitro ...
Jasmin Ezić +5 more
openaire +3 more sources
Delphinidin Exerts Immunomodulatory Effects in Canine Neutrophils and Peripheral Blood Mononuclear Cells by Limiting Tissue Damaging Mechanisms and Regulating Cytokine Responses [PDF]
AnimalsDogs can develop chronic inflammatory diseases that induce progressive tissue damage and illness. Delphinidin is a component of maqui (Aristotelia chilensis) and has anti-inflammatory and antioxidant effects.
Alejandra I. Hidalgo +5 more
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Delphinidin prevents high glucose-induced cell proliferation and collagen synthesis by inhibition of NOX-1 and mitochondrial superoxide in mesangial cells [PDF]
Journal of Pharmacological Sciences, 2016 This study examined the effect of delphinidin on high glucose-induced cell proliferation and collagen synthesis in mesangial cells. Glucose dose-dependently (5.6–25 mM) increased cell proliferation and collagen I and IV mRNA levels, whereas pretreatment ...
Seung Eun Song +5 more
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Delphinidin upregulates microRNA-let-7b expression through family with sequence similarity 222 member B [PDF]
Scientific ReportsDelphinidin is a major anthocyanidin belonging to the flavonoid family with pharmacological activities against cancer, inflammation, and muscle atrophy. However, the mechanism regulating its activity is yet to be completely elucidated.
Motoki Murata +7 more
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