Results 41 to 50 of about 418,629 (276)

Gene expression of the two developmentally regulated dermatan sulfate epimerases in the Xenopus embryo. [PDF]

open access: goldPLoS One, 2018
Gouignard N   +7 more
europepmc   +3 more sources

DSE promotes aggressive glioma cell phenotypes by enhancing HB-EGF/ErbB signaling. [PDF]

open access: yesPLoS ONE, 2018
Remodeling of the extracellular matrix (ECM) in the tumor microenvironment promotes glioma progression. Chondroitin sulfate (CS) proteoglycans appear in the ECM and on the cell surface, and can be catalyzed by dermatan sulfate epimerase to form ...
Wen-Chieh Liao   +7 more
doaj   +1 more source

Analytical techniques for studying structures of dermatan sulfate and low molecular weight dermatan sulfate

open access: green, 1992
A process of chemical depolymerization of dermatan sulfate (DS) byfree radicals ispresented. The low molecular weight dermatan sulfate (LMW-DS) obtained by radicai fragmentation is characterized by physico-chemicalproperties (molecular weight, sulfate/carboxyl ratto, uronic acid percentage, electrophoretic profile), purity (by thè agarose ...
Nicola Volpi   +3 more
openalex   +3 more sources

Glycosaminoglycans in the human cornea: age-related changes [PDF]

open access: yes, 2015
AIM: To investigate possible age-related changes in glycosaminoglycans (GAGs) in the human cornea. The substances today called GAGs were previously referred to as mucopolysaccharides.
Anello, Giulia   +6 more
core   +2 more sources

The role of epidermal growth factor-like module containing mucin-like hormone receptor 2 in human cancers. [PDF]

open access: yes, 2014
G-protein coupled receptors (GPCRs) are among the most diverse and ubiquitous proteins in all of biology. The epidermal growth factor-seven span transmembrane (EGF-TM7) subfamily of adhesion GPCRs is a small subset whose members are mainly expressed on ...
Bloch, Orin   +8 more
core   +2 more sources

Strain-specific joint invasion and colonization by Lyme disease spirochetes is promoted by outer surface protein C.

open access: yesPLoS Pathogens, 2020
Lyme disease, caused by Borrelia burgdorferi, B. afzelii and B. garinii, is a chronic, multi-systemic infection and the spectrum of tissues affected can vary with the Lyme disease strain. For example, whereas B.
Yi-Pin Lin   +6 more
doaj   +1 more source

Electron detachment dissociation of dermatan sulfate oligosaccharides [PDF]

open access: yesJournal of the American Society for Mass Spectrometry, 2008
The structural characterization of glycosaminoglycans (GAG) oligosaccharides has been a long-standing challenge in the field of mass spectrometry. In this work, we present the application of electron detachment dissociation (EDD) Fourier transform mass spectrometry to the analysis of dermatan sulfate (DS) oligosaccharides up to 10 residues long.
Wolff, Jeremy J.   +4 more
openaire   +2 more sources

Arterial pathology in canine mucopolysaccharidosis-I and response to therapy. [PDF]

open access: yes, 2011
Mucopolysaccharidosis-I (MPS-I) is an inherited deficiency of α-L-iduronidase (IdU) that causes lysosomal accumulation of glycosaminoglycans (GAG) in a variety of parenchymal cell types and connective tissues.
Dickson, Patricia I   +6 more
core   +3 more sources

Biosensors for the Detection of Interaction between Legionella pneumophila Collagen-Like Protein and Glycosaminoglycans

open access: yesSensors, 2018
The adhesin Legionella collagen-like (Lcl) protein can bind to extracellular matrix components and mediate the binding of Legionella pneumophila to host cells. In this study, electrochemical impedance spectroscopy (EIS) and surface plasmon resonance (SPR)
Han Su   +4 more
doaj   +1 more source

Metabolomics in psoriatic disease: pilot study reveals metabolite differences in psoriasis and psoriatic arthritis. [PDF]

open access: yes, 2014
ImportanceWhile "omics" studies have advanced our understanding of inflammatory skin diseases, metabolomics is mostly an unexplored field in dermatology.ObjectiveWe sought to elucidate the pathogenesis of psoriatic diseases by determining the differences
Armstrong, April W   +6 more
core   +2 more sources

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