Results 71 to 80 of about 418,629 (276)
Studies on the biosynthesis of dermatan sulfate [PDF]
FEBS Letters, 1971 It is generally accepted that the biosynthesis of polysaccharide proteins in mammalian tissues follows a certain schedule [ 1,2] involving four principal steps: (a) formation of the polypeptide backbone, (b) stepwise addition of monosaccharide units from the appropiate nucleotide sugars to form the linkage j e ion to protein, and (c) the alternate ...
Malmström, A., Fransson, L.-Å.
openaire +2 more sources
Characterization of Danaparoid Complex Extractive Drug by an Orthogonal Analytical Approach
Molecules, 2017 Danaparoid sodium salt, is the active component of ORGARAN, an anticoagulant and antithrombotic drug constituted of three glycosaminoglycans (GAGs) obtained from porcine intestinal mucosa extracts. Heparan sulfate is the major component, dermatan sulfate
Cristina Gardini +5 more
doaj +1 more source
A review on an imperative by-product: Glycosaminoglycans- A holistic approach
Carbohydrate Polymer Technologies and Applications, 2023 Glycosaminoglycan is a generic term for a class of minor but significant components of the body. The extraction, application, and functionalization of GAGs are essential to explore owing to their biological significance.
Bindia Sahu +4 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.HUCMSC‐Apo‐mvs enhance peripheral nerve repair by modulating the inflammatory microenvironment (IME), primarily through coordinated actions on three functional cells. They recruit macrophages and promote their polarization from pro‐inflammatory M1 to anti‐inflammatory M2 phenotypes, increasing secretion of IL‐10 and VEGF.
Haolin Liu +21 more
wiley +1 more source
Advanced Science, EarlyView.This study identifies ESM1 as an endogenous anticoagulant that modulates venous thrombosis. It shows that ESM1 deficiency triggers vascular occlusion in zebrafish and mice, whereas its restoration or overexpression prolongs clot‐formation time. Mechanistic analyses reveal that ESM1 activates HCII through its dermatan‐sulfate chain, uncovering a ...
Changsheng Chen +10 more
wiley +1 more source
Isolation, N-glycosylations and Function of a Hyaluronidase-Like Enzyme from the Venom of the Spider Cupiennius salei. [PDF]
PLoS ONE, 2015 Hyaluronidases are important venom components acting as spreading factor of toxic compounds. In several studies this spreading effect was tested on vertebrate tissue. However, data about the spreading activity on invertebrates, the main prey organisms of
Olivier Biner +10 more
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Frontiers in Microbiology, 2022 Chondroitin sulfate (CS)/dermatan sulfate (DS) is a kind of sulfated polyanionic, linear polysaccharide belonging to glycosaminoglycan. CS/DS sulfatases, which specifically hydrolyze sulfate groups from CS/DS oligo-/polysaccharides, are potential tools ...
Lin Wei +10 more
doaj +1 more source
Extracellular matrix alterations in the Peyronie’s disease
Journal of Advanced Research, 2017 Peyronie’s disease is characterized by fibrous plaque formation of the tunica albuginea, causing penile deformity and fertility problems. The aim of the present study was to investigate alterations in the extracellular matrix in Peyronie’s disease.
Marcelo Silva Watanabe +8 more
doaj +1 more source
Cloned mouse cells with natural killer function and cloned suppressor T cells express ultrastructural and biochemical features not shared by cloned inducer T cells. [PDF]
, 1983 We have examined the morphology, cytochemistry, and biochemistry of mouse leukocyte subsets by analyzing cloned leukocyte populations specialized to perform different immunologic functions.
Cantor, H +10 more
core
Glycosaminoglycan profile in macrophages exposed to Candida albicans and interleukins [PDF]
, 1998 Glycosaminoglycans (GAG), are extracellular matrix macromolecules that affect the phagocytic properties of macrophages. In order to assess whether the interaction between macrophages and Candida albicans (iCa) provokes changes in the phenotype, we ...
BLASI, Elisabetta +8 more
core +1 more source