Results 71 to 80 of about 16,428 (265)
Journal of Inherited Metabolic Disease, Volume 48, Issue 3, May 2025.ABSTRACT This paper reviews biomarkers in lysosomal disease according to their categories and definitions. There are numerous biomarkers in lysosomal diseases. Some are disease or organ‐specific, but most are not. Organ‐specific biomarkers are especially useful, but most biomarkers help with diagnosis, assessing disease severity, prognosis, and ...
Raphael Schiffmann
wiley +1 more source
Collagens and proteoglycans of the corneal extracellular matrix
Brazilian Journal of Medical and Biological Research, 2003 The cornea is a curved and transparent structure that provides the initial focusing of a light image into the eye. It consists of a central stroma that constitutes 90% of the corneal depth, covered anteriorly with epithelium and posteriorly with ...
Y.M. Michelacci
doaj +1 more source
Mass Spectrometry Reviews, Volume 44, Issue 3, Page 213-453, May/June 2025.Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley +1 more source
Galactosaminoglycan Function and Oligosaccharide Structure Determination
The Scientific World Journal, 2007 This review will discuss the importance of sequencing long chondroitin sulfate and dermatan sulfate chains specifically derived from decorin. Decorin is a member of the small leucine-rich repeat proteoglycans and ubiquitously expressed primarily in the ...
Daniela G. Seidler +2 more
doaj +1 more source
Sulodexide: implicazioni cliniche ed economiche
Farmeconomia: Health Economics and Therapeutic Pathways, 2005 Sulodexide is a highly purified glycosaminoglycan approved for leg ulcers treatment. It contains two principal components: heparan sulfate, a fast-moving heparin fraction, (80%) and dermatan sulfate (20%).
Orietta Zaniolo, Mario Eandi
doaj +1 more source
The FASEB Journal, Volume 39, Issue 7, 15 April 2025.Molecular mechanisms in cell‐associated elastic fiber assembly. Abstract Elastogenesis is a cell surface‐located hierarchical process that requires the core components tropoelastin and fibrillins and several accessory proteins, including fibulin‐4 (FBLN4) and latent TGF‐β binding protein‐4 (LTBP4).
Hana Hakami +5 more
wiley +1 more source
Identification of chemically sulfated/desulfated glycosaminoglycans in contaminated heparins and development of a simple assay for the detection of most contaminants in heparin [PDF]
, 2010 Contaminated heparin was linked to at least 149 deaths and hundreds of adverse reactions. Published report indicates that heparin contaminants were a natural impurity, dermatan sulfate, and a contaminant, oversulfated chondroitin sulfate (OSCS). OSCS was
Frazier, Sarah B +7 more
core +1 more source
Changes in glycosaminoglycans and proteoglycans of normal breast and fibroadenoma during the menstrual cycle [PDF]
, 2012 Background: Fibroadenoma is the most common breast tumor in young women, and its growth and metabolism may be under hormonal control. in the present paper we described the proteoglycan (PG) composition and synthesis rate of normal breast and fibroadenoma
Lima, Cilene Reboucas de +3 more
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A Mechanistic Model of Annual Sulfate Concentrations in the United States [PDF]
arXiv, 2020 We develop a mechanistic model to analyze the impact of sulfur dioxide emissions from coal-fired power plants on average sulfate concentrations in the central United States. A multivariate Ornstein-Uhlenbeck (OU) process is used to approximate the dynamics of the underlying space-time chemical transport process, and its distributional properties are ...
arxiv
Mimicking the Dystrophic Cardiac Extracellular Environment through DystroGel
Advanced Healthcare Materials, Volume 14, Issue 9, April 4, 2025.This research introduces DystroGel, a cutting‐edge biocompatible pathological hydrogel derived from decellularized dystrophic porcine heart tissue, suitable for tissue modeling applications. Rheological and proteomic analyses reveal structural and protein composition modifications, underscoring its unique properties.
Maila Chirivì +19 more
wiley +1 more source