Human plasma kallikrein, a serine proteinase, plays a key role in intrinsic blood clotting, in the kallikrein-kinin system, and in fibrinolysis. The proteolytic enzymes involved in these processes are usually controlled by specific inhibitors and may be ...
Gozzo A.J.+7 more
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Identification and Signature Sequences of Bacterial Δ4,5Hexuronate-2-O-Sulfatases
Glycosaminoglycan (GAG) sulfatases, which catalyze the hydrolysis of sulfate esters from GAGs, belong to a large and conserved sulfatase family. Bacterial GAG sulfatases are essential in the process of sulfur cycling and are useful for the structural ...
Shumin Wang+4 more
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Sulodexide. Nephroprotective properties and horizons for use in nephrology
Sulodexide belongs to the class of glycosaminoglycans (GAGs) or mucopolysaccharides. Found in mammalian tissuesm, GAGs regulate the activity of a wide range of proteins (including chemokines, cytokines, growth factors, enzymes, morphogens, and adhesion ...
M. M. Batyushin
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Molecular docking analysis of a dermatan sulfate tetra-saccharide to human alpha-L-iduronidase. [PDF]
Durán-Gutiérrez DP+6 more
europepmc +1 more source
PERAN HEPARIN DALAM ANGIOGENESIS, EPITELIALISASI DAN PENYEMBUHAN LUKA BAKAR
Heparin was initially used in small doses as an anticoagulant in the treatment of burns. It turned out that in addition to the anticoagulant, heparin in larger doses can be used as an anti-inflammatory, accelerate angiogenesis (Polykratis, et al., 2004),
Ruby Riana Asparini
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Structural Diversity of Mammalian Hepatic Dermatan Sulfates.
Dermatan sulfate-proteoglycans (DS-PGs) were extracted from rabbit, rat and bovine defatted livers by magnesium chloride extraction and DEAE-cellulose chromatography, and then submitted successively to Asahipak GS-520 gel filtration chromatography, Asahipak ES-502N anion exchange chromatography, and cellulose acetate membrane electrophoresis.
Kazuhiro Motoki+3 more
openaire +4 more sources
Composition and Anticoagulant Potential of Chondroitin Sulfate and Dermatan Sulfate from Inedible Parts of Garfish (Belone belone). [PDF]
Chikha SB+8 more
europepmc +1 more source
Decorin is one of the proteoglycans expressed in Walker 256 rat mammary carcinoma
Proteoglycan and glycosaminoglycan content was analyzed in a model of rat mammary carcinoma to study the roles of these compounds in tumorigenesis. Hyaluronic acid and proteoglycans bearing chondroitin and/or dermatan sulfate chains were detected in ...
S.M. Oba-Shinjo+4 more
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Data on cloning, expression and biochemical characteristics of a chondroitin sulfate/dermatan sulfate 4-O-endosulfatase. [PDF]
Wei L+9 more
europepmc +1 more source
Endothelial glycocalyx degradation during sepsis: Causes and consequences
The glycocalyx is a ubiquitous structure found on endothelial cells that extends into the vascular lumen. It is enriched in proteoglycans, which are proteins attached to the glycosaminoglycans heparan sulfate, chondroitin sulfate, dermatan sulfate ...
Ryan C. Sullivan+3 more
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